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Identification and nucleotide sequencing of a novel partitivirus derived from Rhizoctonia solani AG-4 HG III isolate A14
Rhizoctonia solani is a widely disseminated phytopathogen that is found in the soil and is capable of harming many important species of crops. Here,...
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Gene silencing in the aedine cell lines C6/36 and U4.4 using long double-stranded RNA
BackgroundRNA interference (RNAi) is a target-specific gene silencing method that can be used to determine gene functions and investigate...
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Emerging role of the RNA-editing enzyme ADAR1 in stem cell fate and function
Stem cells are critical for organism development and the maintenance of tissue homeostasis. Recent studies focusing on RNA editing have indicated how...
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A novel totivirus isolated from the phytopathogenic fungus Rhodosporidiobolus odoratus strain GZ2017
To our knowledge, there have been no reports of mycoviruses infecting Rhodosporidiobolus odoratus . Here, we describe the sequence of a novel...
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Small interfering RNA (siRNA)-based therapeutic applications against viruses: principles, potential, and challenges
RNA has emerged as a revolutionary and important tool in the battle against emerging infectious diseases, with roles extending beyond its...
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Role of mitochondrial stress and the NLRP3 inflammasome in lung diseases
BackgroundAs an organelle essential for intracellular energy supply, mitochondria are involved in intracellular metabolism and inflammation, and cell...
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Complete genome sequence of a novel virus isolated from the phytopathogenic fungus Ceratobasidium sp. AG-A strain SHX-YJLC-1
A novel mycovirus, Ceratobasidium bipartite virus 1 (CBV1), was identified in Ceratobasidium sp. AG-A strain SHX-YJLC-1 isolated from diseased potato...
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Snake River alfalfa virus, a persistent virus infecting alfalfa (Medicago sativa L.) in Washington State, USA
Here we report an occurrence of Snake River alfalfa virus (SRAV) in Washington state, USA. SRAV was recently identified in alfalfa ( Medicago sativa ...
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AI as a Novel Approach for Exploring ccfNAs in Personalized Clinical Diagnosis and Prognosis: Providing Insight into the Decision-Making in Precision Oncology
For many years the idea of personalized medicine has toyed around. It is characterized as an innovative method to alter disease treatment and...
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Use of RNA Interference Technology for Improving Economically Valuable Traits of Cereal Crops
AbstractRNA interference (RNAi) is a new potential tool for plant breeding by introducing small noncoding RNA sequences with the possibility of...
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Complete genome sequence of a novel partitivirus infecting the phytopathogenic fungus Alternaria tenuissima
In the present study, a novel double-stranded RNA (dsRNA) mycovirus designated as "Alternaria tenuissima partitivirus 2" (AttPV2), was isolated from Al...
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A new flavi-like virus identified in populations of wild carrots
We report the discovery of a new flavi-like virus identified in wild carrots ( Daucus carota subsp . carota ), using a double-stranded (ds)RNA...
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From Challenges to Opportunities and Open Questions
An unprecedented pandemic requires unprecedented approaches, including how vaccines are developed and tested. Typically, the development of a new...
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A novel polymycovirus infecting the entomopathogenic fungus Metarhizium brunneum
In this study, at least four distinct double-stranded RNA viruses, including two partitiviruses, one bipartite virus, and a novel polymycovirus, were...
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Seed transmission of raspberry bushy dwarf virus is blocked in Nicotiana benthamiana plants by preventing virus entry into the embryo from the infected embryo sac and endosperm
Raspberry bushy dwarf virus (RBDV) is transmitted through seed in infected red raspberry plants after pollination with pollen grains from healthy red...
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Identification and complete genome sequencing of a novel betapartitivirus naturally infecting the mycorrhizal desert truffle Terfezia claveryi
Viruses that naturally infect fungal species and capable of establishing mycorrhizae are largely unknown. In this study, we identified and...
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Complete genome sequence of the first chrysovirus from the phytopathogenic fungus Alternaria solani on potato in China
The complete genome sequence of a double-stranded RNA (dsRNA) mycovirus that was isolated from Alternaria solani strain DT-10 causing potato foliar...
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Where should siRNAs go: applicable organs for siRNA drugs
RNA interference mediated by small interfering RNAs (siRNAs) has been exploited for the development of therapeutics. siRNAs can be a powerful...
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Evidence for a novel partitivirus isolated from the entomopathogenic nematode Steinernema ceratophorum
Nematodes are abundant, but little is known about their viruses. In this study, we report a novel partitivirus isolated from the entomopathogenic...
