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Dopamine receptors in the anterior cingulate cortex implicate in nicotine enhanced morphine analgesia
RationaleIt is well known that the anterior cingulate cortex (ACC) plays an important role in acute pain perception.
ObjectivesIn the present study,...
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Early anterior cingulate involvement is seen in presymptomatic MAPT P301L mutation carriers
BackgroundPET imaging of glucose metabolism has revealed presymptomatic abnormalities in genetic FTD but has not been explored in MAPT P301L...
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The increased in vivo firing of pyramidal cells but not interneurons in the anterior cingulate cortex after neuropathic pain
Chronic pain damages the balance between excitation and inhibition in the sensory cortex. It has been confirmed that the activity of cortical...
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Role of the Anterior Cingulate Cortex in Translational Pain Research
As the most common symptomatic reason to seek medical consultation, pain is a complex experience that has been classified into different categories...
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Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease
Parkinson’s disease (PD) is a multi-system neurodegenerative disorder. Patients with PD often suffer chronic pain. In the present study, we...
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High-definition transcranial direct current stimulation of the dorsal anterior cingulate cortex modulates decision-making and executive control
Previous neuroimaging evidence highlights the translational implications of targeting the dorsal anterior cingulate cortex (dACC), i.e. a key node of...
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Anterior cingulate cortex metabolites and white matter microstructure: a multimodal study of emergent alcohol use disorder
Multimodal imaging is increasingly used to address neuropathology associated with alcohol use disorder (AUD). Few studies have investigated...
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Brain-derived neurotrophic factor produced long-term synaptic enhancement in the anterior cingulate cortex of adult mice
Previous studies have demonstrated that brain-derived neurotrophic factor (BDNF) is one of the diffusible messengers for enhancing synaptic...
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The behavioral variant of Alzheimer’s disease does not show a selective loss of Von Economo and phylogenetically related neurons in the anterior cingulate cortex
BackgroundThe neurobiological origins of the early and predominant behavioral changes seen in the behavioral variant of Alzheimer’s disease (bvAD)...
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Hypoactivation in the precuneus and posterior cingulate cortex during ambiguous decision making in individuals with HIV
People with human immunodeficiency virus (HIV) often have neurocognitive impairment. People with HIV make riskier decisions when the outcome...
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Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain
Chronic pain easily leads to concomitant mood disorders, and the excitability of anterior cingulate cortex (ACC) pyramidal neurons (PNs) is involved...
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Functional connectivity patterns of the subgenual anterior cingulate cortex in first-episode refractory major depressive disorder
Although accumulating evidence has been elucidating the neuronal basis of refractory/nonrefractory major depressive disorder (rMDD/nrMDD), the...
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Temporal dynamics alterations of spontaneous neuronal activity in anterior cingulate cortex predict suicidal risk in bipolar II patients
Bipolar disorder type II (BD-II) is linked to an increased suicidal risk. Since a prior suicide attempt (SA) is the single most important risk factor...
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The Effect of Optogenetic Inhibition of the Anterior Cingulate Cortex in Neuropathic Pain Following Sciatic Nerve Injury
Cortical disinhibition is the underlying pathological alteration contributing to neuropathic pain associated with peripheral nerve injury. Nerve...
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Functional connectivity of posterior cingulate gyrus in heroin dependents treated by methadone maintenance and protracted abstinence measures: an event-related fMRI study
Protracted abstinence (PA) and Methadone maintenance treatment (MMT) are two main types of heroin addiction treatment, however, the effects of both...
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Anterior Cingulate Cortex Implants for Alcohol Addiction: A Feasibility Study
Abnormal neural activity, particularly in the rostrodorsal anterior cingulate cortex (rdACC), appears to be responsible for intense alcohol craving....
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NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice
IntroductionN-Methyl-D-aspartate receptors (NMDARs) play a critical role in different forms of plasticity in the central nervous system. NMDARs are...
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Ketamine normalizes high-gamma power in the anterior cingulate cortex in a rat chronic pain model
Chronic pain alters cortical and subcortical plasticity, causing enhanced sensory and affective responses to peripheral nociceptive inputs. Previous...
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Functional Impairments in the Large-Scale Resting Networks of the Brain in Opioid Addiction
Objectives. To assess the functional state of large-scale resting brain networks in patients with opioid intoxication. Materials and methods. A total...
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Evidence for a novel subcortical mechanism for posterior cingulate cortex atrophy in HIV peripheral neuropathy
We previously reported that neuropathic pain was associated with smaller posterior cingulate cortical (PCC) volumes, suggesting that a...
