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Hypoxia-Induced Piglet Model of Cardiac Arrest with Assisted Resuscitation by Extracorporeal Membrane Oxygenation
The mortality rate of newborns with severe congenital heart disease (CHD) has significantly decreased over the past few decades. However, many of...
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Cardiac Conduction System: A Generalized Electrical Model
A model of the cardiac conduction system is considered. The model provides an insight into the electrical processes in the myocardium under normal...
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Empagliflozin improves cardiac function in rats with chronic heart failure
The objective of this study is to examine the effect of empagliflozin on cardiac function in rats with chronic heart failure and the possible...
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Strong opioids-induced cardiac, neurologic, and respiratory disorders: a real-world study from 2004 to 2023 based on FAERS
Opioids are mainly used as adjuncts to the induction and maintenance of general anesthesia, postoperative analgesia, and treating moderate to severe...
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One Phenomenon with Many Interpretations: Asymmetry of the Frontal EEG α Rhythm in Healthy People. Part I
The asymmetry of the frontal α rhythm of the EEG as an index of the comparative activity of the left and right prefrontal cortex is an important...
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Lysergic acid diethylamide stimulates cardiac human H2 histamine and cardiac human 5-HT4-serotonin receptors
Lysergic acid diethylamide (LSD) is an artificial hallucinogenic drug. Thus, we hypothesized that LSD might act 5-HT 4 serotonin receptors and/or H 2 ...
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Normal Cardiac Anatomy and Clinical Evaluation
The heart is positioned in the middle, superior, and posterior regions of the mediastinum. Although it is a midline structure, the apex of the heart...
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Disturbance of suprachiasmatic nucleus function improves cardiac repair after myocardial infarction by IGF2-mediated macrophage transition
Suprachiasmatic nucleus (SCN) in mammals functions as the master circadian pacemaker that coordinates temporal organization of physiological...
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Recent Progress in Non-motor Features of Parkinson’s Disease with a Focus on Circadian Rhythm Dysregulation
Parkinson’s disease (PD) is the second most common neurodegenerative disease, which manifests with both motor and non-motor symptoms. Circadian...
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Cellular mechanisms and molecular pathways linking bitter taste receptor signalling to cardiac inflammation, oxidative stress, arrhythmia and contractile dysfunction in heart diseases
Heart diseases and related complications constitute a leading cause of death and socioeconomic threat worldwide. Despite intense efforts and research...
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Intelligent deep model based on convolutional neural network’s and multi-layer perceptron to classify cardiac abnormality in diabetic patients
The ECG is a crucial tool in the medical field for recording the heartbeat signal over time, aiding in the identification of various cardiac...
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A Signal Processing Framework for the Detection of Abnormal Cardiac Episodes
MotivationCardiologists rely on the long duration Holter electrocardiogram (ECG) recordings in general for assessment of abnormal episodes and such...
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Through the Looking Glass: The Paradoxical Evolution of Targeted Temperature Management for Comatose Survivors of Cardiac Arrest
For the past two decades, targeted temperature management (TTM) has been a staple in the care of comatose survivors following cardiac arrest....
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Evaluation of cardiac autonomic control during the 6-min walk test in women with systemic sclerosis
ObjectiveTo evaluate the association between sympathovagal balance and exercise performance, as measured by the 6-min walk test (6MWT), in women with...
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The Neuro-cardiac Axis in Arrhythmogenesis: Role and Impact of Autonomic Modulation
The autonomic nervous system consisting of two limbs, the sympathetic and parasympathetic nervous system, plays a key role in the modulation of...
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Circadian rhythm as a therapeutic target
The circadian clock evolved in diverse organisms to integrate external environmental changes and internal physiology. The clock endows the host with...
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Review of cardiac safety in onasemnogene abeparvovec gene replacement therapy: translation from preclinical to clinical findings
Human gene replacement therapies such as onasemnogene abeparvovec (OA) use recombinant adeno-associated virus (rAAV) vectors to treat monogenic...
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The network of cardiac KIR2.1: its function, cellular regulation, electrical signaling, diseases and new drug avenues
The functioning of the human heart relies on complex electrical and communication systems that coordinate cardiac contractions and sustain...
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An Overview of Spiral- and Scroll-Wave Dynamics in Mathematical Models for Cardiac Tissue
We provide a brief overview of recent numerical studies of spiral- and scroll-wave dynamics in mathematical models of cardiac tissue. These waves are...
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Reversible dysregulation of renal circadian rhythm in lupus nephritis
BackgroundWe have found disruption of expression of major transcriptional regulators of circadian rhythm in the kidneys of several mouse models of...
