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Zebrafish: A Metamorphosis in Ophthalmological Research—A Literature Review
Ophthalmological disorders causing impaired vision is a global problem affecting millions of individuals. Animal models having the same type of...
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Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health
Fungi of the genus Alternaria are ubiquitous plant pathogens and saprophytes which are able to grow under varying temperature and moisture conditions...
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CASA: A Suitable Tool for Epidemiology and Reprotox Studies
Basic computer-aided sperm analysis (CASA) was first developed in the 1980s to track sperm motion. However, like all applications of information...
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Optical and Electrochemical Aptasensors for Sensitive Detection of Aflatoxin B1 and Aflatoxin M1 in Blood Serum, Grape Juice, and Milk Samples
Aflatoxin food contamination with toxic and carcinogenic impacts on human health is a global concern. We have developed aptasensors for the detection...
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The role of pyroptosis in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the main histologic type of liver cancer. It accounts for the majority of all diagnoses and deaths due to liver...
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Chronic oral exposure to low-concentration fumonisin B2 significantly exacerbates the inflammatory responses of allergies in mice via inhibition of IL-10 release by regulatory T cells in gut-associated lymphoid tissue
Contamination with fumonisins produced by Fusarium spp. is rapidly growing in both develo** and developed countries. The purpose of this study was...
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Investigating the applicability domain of the hiPSC-based PluriLum assay: an embryotoxicity assessment of chemicals and drugs
To meet the growing demand for developmental toxicity assessment of chemicals, New Approach Methodologies (NAMs) are needed. Previously, we developed...
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Soluble Guanylyl Cyclase Alpha1 Subunit as a Biomarker of Toxicity: Applications to Investigate Endocrine-Disrupting Chemicals
Endocrine-disrupting chemicals (EDCs) are a growing group of naturally occurring and synthetic substances in the environment that negatively impacts...
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Prevalence of Mycotoxins and Their Consequences on Human Health
Mycotoxin contamination is a global phenomenon and causes a wide array of negative effects and other complications. This study focused on commonly...
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Mycotoxins in Herbal Medicines
The medicinal plants are at risk of contamination by different fungi during harvesting, distribution, and storage. The contamination by different...
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Evaluation of subchronic oral dose toxicity and allergen of freeze-dried powder of Locusta migratoria (Orthoptera: Acrididae) as a novel food source
The migratory locust, Locusta migratoria (Orthoptera: Acrididae), is a well-known edible insect which may serve as new source of human food and...
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Natural Toxicants Originating from Food/Diet
Even though many of the toxic chemicals found in our environment that concern the general public are man-made, there are also hundreds of naturally...
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Biological Synthesis of Nanoparticles: Fungi
Fungi are multicellular, eukaryotic life forms that lack chlorophyll and play a major role in nutrient and carbon cycling in the biosphere as...
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Ochratoxin A induces nephrotoxicity in vitro and in vivo via pyroptosis
Ochratoxin A (OTA), a prevalent nephrotoxic mycotoxin contaminant in food and feedstuff, has been reported to induce renal injury. To disclose the...
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Single-Domain Antibody-Gold Nanoparticle Bioconjugates as Immunosensors for the Detection of Hantaviruses
IntroductionHantavirus, a zoonotic pathogen, causes severe syndromes like hemorrhagic fever with renal syndrome (HFRS), sometimes fatal in humans....
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Multi-omics reveal mechanisms of high enteral starch diet mediated colonic dysbiosis via microbiome-host interactions in young ruminant
BackgroundAlthough rumen development is crucial, hindgut undertakes a significant role in young ruminants’ physiological development. High-starch...
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Sperm epigenetics and male infertility: unraveling the molecular puzzle
BackgroundThe prevalence of infertility among couples is estimated to range from 8 to 12%. A paradigm shift has occurred in understanding of...
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Mechanisms Involved in Carcinogenesis
The initiation of human cancer is primarily driven by carcinogenic substances including chemicals, radiations, viruses, and parasites. The...
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Mechanics of Uterosacral Ligaments: Current Knowledge, Existing Gaps, and Future Directions
The uterosacral ligaments (USLs) are important anatomical structures that support the uterus and apical vagina within the pelvis. As these structures...
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Enzyme Engineering Strategies for the Bioenhancement of l-Asparaginase Used as a Biopharmaceutical
Over the past few years, there has been a surge in the industrial production of recombinant enzymes from microorganisms due to their catalytic...
