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Translational changes induced by acute sleep deprivation uncovered by TRAP-Seq
Sleep deprivation is a global health problem adversely affecting health as well as causing decrements in learning and performance. Sleep deprivation...
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Measuring mosquito control: adult-mosquito catches vs egg-trap data as endpoints of a cluster-randomized controlled trial of mosquito-disseminated pyriproxyfen
BackgroundAedes aegypti and Culex quinquefasciatus are the main urban vectors of arthropod-borne viruses causing human disease, including dengue,...
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A robust deep learning workflow to predict CD8 + T-cell epitopes
BackgroundT-cells play a crucial role in the adaptive immune system by triggering responses against cancer cells and pathogens, while maintaining...
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Field comparison of broad-spectrum white LED-baited traps with narrow-spectrum green LED-baited traps in the capture of Anopheles mosquitoes (Diptera: Culicidae)
Light-Emitting Diodes (LEDs) have been effective light sources in attracting Anopheles mosquitoes, but the broad-spectrum white light, even with a...
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Field evaluation of an automated mosquito surveillance system which classifies Aedes and Culex mosquitoes by genus and sex
BackgroundMosquito-borne diseases are a major concern for public and veterinary health authorities, highlighting the importance of effective vector...
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The diversity of unique 1,4,5,6-Tetrahydro-2-methyl-4-pyrimidinecarboxylic acid coding common genes and Universal stress protein in Ectoine TRAP cluster (UspA) in 32 Halomonas species
ObjectivesTo decipher the diversity of unique ectoine-coding housekee** genes in the genus Halomonas .
ResultsIn Halomonas ,...
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Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer
Local adaptation directs populations towards environment-specific fitness maxima through acquisition of positively selected traits. However, rapid...
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miR-92a-1-5p enriched prostate cancer extracellular vesicles regulate osteoclast function via MAPK1 and FoxO1
BackgroundWe have previously reported that extracellular vesicles (EVs) derived from osteoblastic, osteoclastic and mixed prostate cancer cells...
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Traffic-related air pollution and supplemental folic acid intake in relation to DNA methylation in granulosa cells
BackgroundHigher exposure to traffic-related air pollution (TRAP) is related to lower fertility, with specific adverse effects on the ovary. Folic...
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X-linked recessive ichthyosis in 8 Tunisian patients: awareness of misdiagnosis due to the technical trap of the STS pseudogene
IntroductionX-linked recessive ichthyosis (XLI) is a genodermatosis, caused by a deficiency of the steroid sulphatase enzyme encoded by the STS gene...
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Identification of potential biological processes and key genes in diabetes-related stroke through weighted gene co-expression network analysis
BackgroundType 2 diabetes mellitus (T2DM) is an established risk factor for acute ischemic stroke (AIS). Although there are reports on the...
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SOST gene suppression stimulates osteocyte Wnt/β-catenin signaling to prevent bone resorption and attenuates particle-induced osteolysis
AbstractThe most common cause for prosthetic revision surgery is wear particle-induced periprosthetic osteolysis, which leads to aseptic loosening of...
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Fine-scale genomic tracking of Ross River virus using nanopore sequencing
BackgroundRoss River virus (RRV) is Australia’s most common and widespread mosquito-transmitted arbovirus and is of significant public health...
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Semi-field evaluation of freestanding transfluthrin passive emanators and the BG sentinel trap as a “push-pull control strategy” against Aedes aegypti mosquitoes
BackgroundSpatial repellents that drive mosquitoes away from treated areas, and odour-baited traps, that attract and kill mosquitoes, can be combined...
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Chordoma cells possess bone-dissolving activity at the bone invasion front
PurposeChordomas are malignant tumors that destroy bones, compress surrounding nerve tissues and exhibit phenotypes that recapitulate notochordal...
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Exploring the therapeutic potential of isoorientin in the treatment of osteoporosis: a study using network pharmacology and experimental validation
BackgroundIsoorientin (ISO) is a glycosylated flavonoid with antitumor, anti-inflammatory, and antioxidant properties. However, its effects on bone...
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Cell fusing agent virus (Flavivirus) infection in Aedes aegypti in Texas: seasonality, comparison by trap type, and individual viral loads
South Texas has experienced local transmission of Zika virus and of other mosquito-borne viruses such as chikungunya virus and dengue virus in the...
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The mosquito electrocuting trap as an exposure-free method for measuring human-biting rates by Aedes mosquito vectors
BackgroundEntomological monitoring of Aedes vectors has largely relied on surveillance of larvae, pupae and non-host-seeking adults, which have been...
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Concentration-dependent increase in symptoms due to diesel exhaust in a controlled human exposure study
BackgroundTraffic-related air pollution (TRAP) exposure causes adverse effects on wellbeing and quality of life, which can be studied non-invasively...