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Short term depression, presynaptic inhibition and local neuron diversity play key functional roles in the insect antennal lobe
As the oldest, but least understood sensory system in evolution, the olfactory system represents one of the most challenging research targets in...
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The Sense of Smell: Role of the Olfactory System in Social Behavior
Olfaction is the sense of smell, which is mediated by specialized sensory neurons in the nasal cavity. Classically, the olfactory system is divided...
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Olfactory Bulb Excitotoxicity as a Gap-Filling Mechanism Underlying the Link Between Traumatic Brain Injury-Induced Secondary Neuronal Degeneration and Parkinson’s Disease-Like Pathology
There is increasing preclinical and clinical data supporting a potential association between Traumatic Brain Injury (TBI) and Parkinson’s disease...
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Screening Methods for the Evaluation of Drugs for Learning and Memory
Various diseases like Alzheimer’s disease (AD), frontotemporal dementia, dementia with Lewy bodies, HIV-induced dementia, etc., affect humans’ memory...
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Open-Source JL Olfactometer for Awake Behaving Recording of Brain Activity for Mice Engaged in Olfactory Tasks
Automated olfactometers are used to study brain function in rodents engaged in olfactory behavioral tasks. In this chapter, we describe the JL...
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The Synergistic Effect Study of Lipopolysaccharide (LPS) and A53T-α-Synuclein: Intranasal LPS Exposure on the A53T-α-Synuclein Transgenic Mouse Model of Parkinson’s Disease
Aging and interactions between genetic and environmental factors are believed to be involved the chronic development of Parkinson’s disease (PD)....
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Protective effects of intracerebroventricular adiponectin against olfactory impairments in an amyloid β1–42 rat model
BackgroundAlzheimer’s disease (AD) is characterized by cognitive impairment that eventually develops into dementia. Amyloid-beta (Aβ) accumulation is...
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The Bruce Effect: Complementary Roles of Olfactory Memory and Male-Sourced Estradiol
Uterine implantation of fertilized ova is a highly sensitive transition from minimal maternal investment to increasing devotion of resources to...
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Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71
Polybrominated diphenyl ethers (PBDEs) are ubiquitous persistent organic pollutants (POPs) that are known neuroendocrine disrupting chemicals with...
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Olfactory processing in the lateral horn of Drosophila
Sensing olfactory signals in the environment represents a crucial and significant task of sensory systems in almost all organisms to facilitate...
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Rapid olfactory discrimination learning in adult zebrafish
The zebrafish is a model organism to study olfactory information processing, but efficient behavioral procedures to analyze olfactory discrimination...
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Lessons from behavioral lateralization in olfaction
Sensory information, sampled by sensory organs positioned on each side of the body may play a crucial role in organizing brain lateralization. This...
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Does Olfactory Training Improve Brain Function and Cognition? A Systematic Review
Olfactory training (OT), or smell training,consists of repeated exposure to odorants over time with the intended neuroplastic effect of improving or...
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Neural processing of odor-associated words: an fMRI study in patients with acquired olfactory loss
Perception of olfactory information is mediated by both bottom-up (from molecules to perception) and top-down (e.g. cross-modal associative learning)...
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A Multidisciplinary Approach Towards Finding and Treating All Tuberculosis Patients
Tuberculosis (TB) is an old disease but not a disease of the past. Despite a global plan to End TB, it is still among the leading causes of...
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ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the...
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Molecular and functional characterization of a conserved odorant receptor from Aedes albopictus
BackgroundThe Asian tiger mosquito Aedes albopictus is a competent vector of several viral arboviruses including yellow fever, dengue fever, and...
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Use of an Automated Mouse Touchscreen Platform for Quantification of Cognitive Deficits After Central Nervous System Injury
Analyzing cognitive performance is an important aspect of assessing physiological deficits after stroke or other central nervous system (CNS)...
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Influence of age on nicotinic cholinergic regulation of blood flow in rat’s olfactory bulb and neocortex
The olfactory bulb receives cholinergic basal forebrain inputs as does the neocortex. With a focus on nicotinic acetylcholine receptors (nAChRs),...
