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Biosensors and their applications in detection of organophosphorus pesticides in the environment
This review discusses the past and recent advancements of biosensors focusing on detection of organophosphorus pesticides (OPs) due to their...
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Stem Cells in Neurotoxicology/Developmental Neurotoxicology: Current Scenario and Future Prospects
Stem cell biology has played a pivotal role in the field of disease modeling, regenerative medicine, and tissue engineering. The scope of stem cell...
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Adoptive Autophagy Activation: a Much-Needed Remedy Against Chemical Induced Neurotoxicity/Developmental Neurotoxicity
The profound significance of autophagy as a cell survival mechanism under conditions of metabolic stress is a well-proven fact. Nearly a decade-long...
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Differentiating neurons derived from human umbilical cord blood stem cells work as a test system for developmental neurotoxicity
Differentiating neuronal cells derived from human umbilical cord blood stem cells have been used as an in vitro tool for the assessment of...
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An Overview on Human Umbilical Cord Blood Stem Cell-Based Alternative In Vitro Models for Developmental Neurotoxicity Assessment
The develo** brain is found highly vulnerable towards the exposure of different environmental chemicals/drugs, even at concentrations, those are...
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General Quality Control Methods
Take about 2 g of Danshen granules or chips (with diameter not more than 3 mm), precisely weighed, and place in a weighing bottle that has been dried...
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The beneficial effects of ascorbic acid during chlorpyrifos-induced oxidative stress and histopathological changes in Oreochromis spilurus
This study was aimed to evaluate the oxidative stress and histopathological changes of chlorpyrifos (CPF; Dursban 48) on sub-adult Oreochromis spilurus ...
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Chronic Toxicity of Organophosphorus Compounds
Organophosphorus compounds (OPs) have been widely used, mainly in agriculture. During the last few decades, organophosphorus pesticides have replaced...
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4-Hydroxy-trans-2-nonenal (4-HNE) induces neuronal SH-SY5Y cell death via hampering ATP binding at kinase domain of Akt1
Inhibition mechanism(s) of protein kinase B/Akt1 and its consequences on related cell signaling were investigated in human neuroblastoma SH-SY5Y...
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Acute Toxicity of Organophosphorus Compounds
Whilst a useful group of insecticides, organophosphorus (OP) pesticides represent a major cause of toxicity and mortality in individuals experiencing...
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Lead Intoxication Synergies of the Ethanol-Induced Toxic Responses in Neuronal Cells—PC12
Lead (Pb)-induced neurodegeneration and its link with widespread neurobehavioral changes are well documented. Experimental evidences suggest that...
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Occupational and Environmental Aspects of Organophosphorus Compounds
Besides being a potential risk to humans and other living organisms, organophosphorus (OP) compounds also poses a risk to the environment. Production...
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Lipid Integration in Neurodegeneration: An Overview of Alzheimer’s Disease
Various types of lipids and their metabolic products associated with the biological membrane play a crucial role in signal transduction, modulation,...
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Chemistry and Classification of OP Compounds
The term organophosphorus (OP) compounds refers to any group of organic chemicals that contain phosphorus. The most predominant valances of...
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Toxicity and Novel Biomarkers of OP Exposure
This chapter consists of two different topics which are extremely important in the toxicity of organophosphorus (OP) compounds. The first part is...
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History of the Use and Epidemiology of Organophosphorus Poisoning
Organophosphorus (OP) compounds are organic derivatives of phosphorus that have largely been used as pesticides and nerve agents....
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A Prospective Study on Electrocardiographic Findings of Patients with Organophosphorus Poisoning
Organophosphate (OP) compounds are widely used in different applications including agriculture. The widespread use of OP insecticides, however,...
