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The Use and Predictability of C. elegans as an Alternative and Complementary Model in Neurotoxicological Studies: Focus on the Dopaminergic System
Several alternative models have been used to create new studies on central nervous system (CNS) function. The benefits associated with these...
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Calcium channel inhibitor and extracellular calcium improve aminoglycoside-induced hair cell loss in zebrafish
Aminoglycosides are commonly used antibiotics for treatment of gram-negative bacterial infections, however, they might act on inner ear, leading to...
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Adhesion G protein-coupled receptor gluing action guides tissue development and disease
Phylogenetic analysis of human G protein-coupled receptors (GPCRs) divides these transmembrane signaling proteins into five groups: glutamate,...
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Hemodynamic Control of Endothelial Cell Fates in Development
The vascular system initially forms as a random network of capillaries, which remodels under the influence of flow into efficient, hierarchical...
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Shc and the Control of Small GTPase Dynamics in Cellular Anchorage
Specialized metazoan cells have diverse functions which require them to interact differently with the body’s matrix scaffolds. Resident tissue cells,...
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Effect of Octopamine on the Frequency Tuning of the Auditory System in Culex Pipiens Pipiens Mosquito (Diptera, Culicidae)
We aimed to demonstrate the direct physiological effects of octopamine on the auditory responses of Johnston’s organ sensory neurons in Culex pipiens...
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An infection of Enterobacter ludwigii affects development and causes age-dependent neurodegeneration in Drosophila melanogaster
AbstractThe effects of teeth-blackening bacteria Enterobacter ludwigii on the physiological system were investigated using the model organism Drosophi...
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Spinal Afferent Innervation of the Uterus
The extrinsic neural innervation of the uterus plays an important role in modulating uterine functions that are critical to reproductive success. Its...
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Unintentionally intentional: unintended effects of spinal stimulation as a platform for multi-modal neurorehabilitation after spinal cord injury
Electrical stimulation of spinal neurons has emerged as a valuable tool to enhance rehabilitation after spinal cord injury. In separate...
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Neurogenetic Analysis in Caenorhabditis elegans
The goal of this chapter is to introduce the Caenorhabditis elegans model and how it can be used to address fundamental questions in neurobiology...
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Neurons in the caudal ventrolateral medulla mediate descending pain control
Supraspinal brain regions modify nociceptive signals in response to various stressors including stimuli that elevate pain thresholds. The medulla...
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Dense neuronal reconstruction through X-ray holographic nano-tomography
Imaging neuronal networks provides a foundation for understanding the nervous system, but resolving dense nanometer-scale structures over large...
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Investigating sensory processing in the pectines of the striped bark scorpion, Centruroides vittatus
Scorpion pectines detect chemical and physical stimuli via thousands of peg sensilla on ground-facing teeth. Each sensillum has multiple neurons that...
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The Development and Evolution of Lateral Line Electroreceptors: Insights from Comparative Molecular Approaches
In the jawless lampreys, most nonteleost jawed fishes, and aquatic-stage amphibians, the lateral line system has a mechanosensory division responding...