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Novel adenovirus associated with common tern (Sterna hirundo) chicks
Adenoviruses have been identified in a wide variety of avian species, and in some species, they have been shown to cause disease and increase...
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High-intensity interval training in allogeneic adoptive T-cell immunotherapy – a big HIT?
BackgroundAdoptive transfer of virus-specific T cells (VSTs) represents a prophylactic and curative approach for opportunistic viral infections and...
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Identification and genetic characterization of an isolate of bovine adenovirus 7 from the United States, a putative member of a new species in the genus Atadenovirus
The bovine adenovirus 7 (BAdV-7) isolate SD18-74 was recovered from lung tissue of calves in South Dakota. The 30,043-nucleotide (nt) genome has the...
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Otus scops adenovirus: the complete genome sequence of a novel aviadenovirus discovered in a wild owl
We present the complete genome sequence of an aviadenovirus obtained by metagenomics from cloacal swabs taken from a free-living Eurasian scops owl ( O...
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Broad sialic acid usage amongst species D human adenovirus
Human adenoviruses (HAdV) are widespread pathogens causing usually mild infections. The Species D (HAdV-D) cause gastrointestinal tract infections...
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First report of fowl aviadenovirus serotypes FAdV-8b and FAdV-11 associated with inclusion body hepatitis in commercial broiler and broiler-breeder flocks in Turkey
Inclusion body hepatitis (IBH), hydropericardium syndrome (HS), and gizzard erosion (GE) are all economically important diseases in the poultry...
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Host and geography impact virus diversity in New Zealand’s longfin and shortfin eels
The fishing and aquaculture industry is vital for global food security, yet viral diseases can result in mass fish die-off events. Determining the...
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Genotype Diversity of Enteric Viruses in Wastewater Amid the COVID-19 Pandemic
Viruses remain the leading cause of acute gastroenteritis (AGE) worldwide. Recently, we reported the abundance of AGE viruses in raw sewage water...
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Occurrence of Human Enteric Viruses in Water Sources and Shellfish: A Focus on Africa
Enteric viruses are a diverse group of human pathogens which are primarily transmitted by the faecal–oral route and are a major cause of...
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An Overview of the Cell Biology and Genetic Barriers to Virus Infections with Implications in Cell Line Development for Virotherapy
Viruses can be engineered for oncolysis, gene therapy, or vaccines. Oncolytic viruses and viral vector for cell and gene therapies are promising...
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Observation of Bacteriophage Ultrastructure by Cryo-Electron Microscopy
Transmission electron microscopy (TEM) is an ideal method to observe and determine the structure of bacteriophages. From early studies by negative...
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Human Coronavirus NL63 Among Other Respiratory Viruses in Clinical Specimens of Egyptian Children and Raw Sewage Samples
The objective of this study was to investigate human coronavirus NL63 (HCoV-NL63) prevalence among the other respiratory viruses such as...
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Adenovirus Vectors
Infectious diseases are the prime cause of morbidity and mortality in animals leading to heavy economic losses to the livestock/poultry industry. One...
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SARS-CoV-2 vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals low levels of viral backbone gene transcription alongside very high levels of SARS-CoV-2 S glycoprotein gene transcription
BackgroundChAdOx1 nCoV-19 is a recombinant adenovirus vaccine against SARS-CoV-2 that has passed phase III clinical trials and is now in use across...
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Characterization and oncolytic virus targeting of FAP-expressing tumor-associated pericytes in glioblastoma
Cancer-associated fibroblasts (CAFs) are activated fibroblasts constituting the major stromal components in many types of cancer. CAFs contribute to...
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Challenges and progress toward tumor-targeted therapy by systemic delivery of polymer-complexed oncolytic adenoviruses
Oncolytic adenovirus (oAd) elicits antitumor activity by preferential viral replication in cancer cells. However, poor systemic administrability or...
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Oncolytic Viruses and Viral Gene Therapy Vectors: Principles of Safety
With the emergence of genetic engineering, a new era of viral safety was introduced. Apart from the means to attenuate classical viral vaccines, new...
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Small-size recombinant adenoviral hexon protein fragments for the production of virus-type specific antibodies
BackgroundAdenoviruses are common pathogens infecting animals and humans. They are classified based on serology, or genome sequence information....
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Circulation of unusual and diverse enteric virus strains in adults with acute gastroenteritis: a study from Pune (Maharashtra), Western India
In India, studies on the epidemiological and genetic characteristics of enteric viruses in adults with acute gastroenteritis (AGE) are lacking. In...
