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Being precise with anticoagulation to reduce adverse drug reactions: are we there yet?
Anticoagulants are potent therapeutics widely used in medical and surgical settings, and the amount spent on anticoagulation is rising. Although...
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Brief Recognition History of Echinococcus Tapeworm
The cognitive history of Echinococcus began with the description of the diseases it caused by doctors more than 2000 years ago, but it was not until...
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Quantifying Enzyme Activity and Gene Expression Within Single Cells Using a Multiplexed Capillary Electrophoresis Platform
To date, numerous chemical cytometry platforms have been developed to study a wide range of biologically relevant analytes in single cells by...
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Knockdown of the Non-canonical Wnt Gene Prickle2 Leads to Cerebellar Purkinje Cell Abnormalities While Cerebellar-Mediated Behaviors Remain Intact
Autism spectrum disorders (ASD) involve brain wide abnormalities that contribute to a constellation of symptoms including behavioral inflexibility,...
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A Perspective on the Molecular Identification, Classification, and Epidemiology of Enterocytozoon bieneusi of Animals
The microsporidian Enterocytozoon bieneusi is an obligate intracellular pathogen that causes enteric disease (microsporidiosis) in humans and has...
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Dominant infection of Cryptosporidium baileyi in broiler chickens in Zhejiang Province, China
Cryptosporidium is a common enteric parasite in chickens. A total of 812 fecal specimens were collected from 11 broiler farms in Zhejiang Province,...
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Pharmacogenetic and clinical risk factors for bevacizumab-related gastrointestinal hemorrhage in prostate cancer patients treated on CALGB 90401 (Alliance)
The objective of this study was to discover clinical and pharmacogenetic factors associated with bevacizumab-related gastrointestinal hemorrhage in...
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Apicomplexans in small mammals from Chile, with the first report of the Babesia microti group in South American rodents
Small mammals play an essential role as disseminators of pathogens because they reach high population densities and have ubiquitous distributions. In...
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Pharmacogenomics of Alzheimer’s Disease: Novel Strategies for Drug Utilization and Development
Alzheimer’s disease (AD) is a priority health problem in developed countries with a high cost to society. Approximately 20% of direct costs are...
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Molecular Detection and Genoty** of Cryptosporidium spp. Isolates from Bats in Colombia
PurposeCryptosporidiosis is a zoonotic infectious disease caused by the protozoan parasite Cryptosporidium spp., frequently found in several animal...
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A G3P[9] rotavirus strain with an unusual genome constellation in a diarrheic cat in Thailand
Rotavirus infection can cause diarrhea in many animal species. A 2-year-old indoor female Siamese cat with bloody mucoid diarrhea tested positive for...
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Tumor Markers in Early Detection and Monitoring of Prostate Cancer: Recent Advances
Due to the fact that the use of prostate-specific antigen (PSA) in prostate cancer (PC) management is limited, the search for novel biomarkers useful...
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A Brief Historical Overview of the Discovery of Arboviruses in the USSR and Russia
The discovery and study of causative agents of important human arbovirus diseases, such as tick-borne encephalitis, Crimean-Congo hemorrhagic fever,...
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Molecular detection of Cryptosporidium and Enterocytozoon bieneusi in dairy calves and sika deer in four provinces in Northern China
The protistan pathogens Cryptosporidium and Enterocytozoon bieneusi can cause significant intestinal diseases in animals and humans. However, limited...
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TUBB3 Arg262His causes a recognizable syndrome including CFEOM3, facial palsy, joint contractures, and early-onset peripheral neuropathy
Microtubules are formed from heterodimers of alpha- and beta-tubulin, each of which has multiple isoforms encoded by separate genes. Pathogenic...
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Molecular characterization of the waterborne pathogens Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi, Cyclospora cayetanensis and Eimeria spp. in wastewater and sewage in Guangzhou, China
BackgroundThe waterborne pathogens Cryptosporidium spp., Giardia duodenalis , Enterocytozoon bieneusi and Cyclospora cayetanensis can cause...
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Rotavirus Surveillance in Tap Water, Recycled Water, and Sewage Sludge in Thailand: A Longitudinal Study, 2007–2018
The objective of this study was to describe the epidemiological and molecular surveillance of rotaviruses in tap water, recycled water, and sewage...
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Mitochondrial genetic variation and risk of chronic kidney disease and acute kidney injury in UK Biobank participants
Experimental models suggest an important role for mitochondrial dysfunction in the pathogenesis of chronic kidney disease (CKD) and acute kidney...
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Occurrence and genetic diversity of Enterocytozoon bieneusi (Microsporidia) in owned and sheltered dogs and cats in Northern Spain
Enterocytozoon bieneusi is an obligate intracellular protist-like fungi parasite that infects numerous mammal hosts including humans, raising...
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Ultrastructural analysis of breast cancer patient-derived organoids
BackgroundBreast cancer Patient Derived Organoids (PDO) have been demonstrated to be a reliable model to study cancer that promised to replace and...
