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Showing 41-60 of 10,000 results
  1. Soluble TREM2 is associated with death and cardiovascular events after acute ischemic stroke: an observational study from CATIS

    Background

    Soluble triggering receptor expressed on myeloid cells 2 (sTREM2), which reflects microglia activation, has been reported closely...

    Yaling Lu, Yu Zhao, ... Chongke Zhong in Journal of Neuroinflammation
    Article Open access 12 April 2022
  2. Cardiovascular Diseases and Cognitive Impairments

    As life expectancy increases, combinations of cardiovascular disease (CVD) with cognitive impairment and dementia are increasingly common. Cognitive...

    S. A. Boytsov, I. V. Samorodskaya in Neuroscience and Behavioral Physiology
    Article 01 February 2023
  3. Long-term kidney outcomes of semaglutide in obesity and cardiovascular disease in the SELECT trial

    The SELECT trial previously reported a 20% reduction in major adverse cardiovascular events with semaglutide ( n  = 8,803) versus placebo ( n = 8,801)...

    Helen M. Colhoun, Ildiko Lingvay, ... A. Michael Lincoff in Nature Medicine
    Article Open access 25 May 2024
  4. Circulating Lipoproteins Mediate the Association Between Cardiovascular Risk Factors and Cognitive Decline: A Community-Based Cohort Study

    Cardiovascular health metrics are now widely recognized as modifiable risk factors for cognitive decline and dementia. Metabolic perturbations might...

    Jialin Li, Qingxia Huang, ... Yanfeng Jiang in Phenomics
    Article 21 September 2023
  5. Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases

    Spatial multi-omic studies have emerged as a promising approach to comprehensively analyze cells in tissues, enabling the joint analysis of multiple...

    Paul Kiessling, Christoph Kuppe in Genome Medicine
    Article Open access 18 January 2024
  6. A Systematic Analysis of Additive Manufacturing Techniques in the Bioengineering of In Vitro Cardiovascular Models

    Additive Manufacturing is noted for ease of product customization and short production run cost-effectiveness. As our global population approaches 8...

    Hemanth Ponnambalath Mohanadas, Vivek Nair, ... Saravana Kumar Jaganathan in Annals of Biomedical Engineering
    Article Open access 19 July 2023
  7. Metabolomic phenoty** of obesity for profiling cardiovascular and ocular diseases

    Background

    We aimed to evaluate the impacts of metabolomic body mass index (metBMI) phenotypes on the risks of cardiovascular and ocular diseases...

    **ting Zhong, Shaoying Tan, ... Wei Wang in Journal of Translational Medicine
    Article Open access 12 June 2023
  8. Evaluation of CTRL: a web application for dynamic consent and engagement with individuals involved in a cardiovascular genetic disorders cohort

    There has been keen interest in whether dynamic consent should be used in health research but few real-world studies have evaluated its use....

    Matilda A. Haas, Evanthia O. Madelli, ... Tiffany Boughtwood in European Journal of Human Genetics
    Article Open access 14 September 2023
  9. Sex matters in the association between cardiovascular health and incident dementia: evidence from real world data

    Background

    Cardiovascular health has been associated with dementia onset, but little is known about the variation of such association by sex and age...

    Anna Ponjoan, Jordi Blanch, ... Rafel Ramos in Alzheimer's Research & Therapy
    Article Open access 14 March 2024
  10. Impact of BMI on patient outcome in acute myeloid leukaemia patients receiving intensive induction therapy: a real-world registry experience

    Background

    Acute myeloid leukaemia (AML) is treated with intensive induction chemotherapy (IT) in medically fit patients. In general, obesity was...

    Julius C. Enßle, Sebastian Wolf, ... Björn Steffen in British Journal of Cancer
    Article Open access 04 August 2023
  11. Renin-Angiotensin System in Chronic Kidney Disease: Implications in Stroke Outcome

    Stroke has an intricate pathophysiology and aggravation of that often leads to co-morbidities. Chronic kidney disease is devastating and plays an...
    Aishika Datta, Deepaneeta Sarmah, ... Pallab Bhattacharya in The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases
    Chapter 2023
  12. Long-term cardiovascular outcomes of COVID-19

    The cardiovascular complications of acute coronavirus disease 2019 (COVID-19) are well described, but the post-acute cardiovascular manifestations of...

    Yan **e, Evan Xu, ... Ziyad Al-Aly in Nature Medicine
    Article Open access 07 February 2022
  13. Effect of digoxin on all-cause and cardiovascular mortality in patients with atrial fibrillation with and without heart failure: an umbrella review of systematic reviews and 12 meta-analyses

    Purpose

    To perform a systematic umbrella review with meta-analysis to evaluate the certainty of evidence on mortality risk associated with digoxin use...

    Gianluca Gazzaniga, Danilo Menichelli, ... Daniele Pastori in European Journal of Clinical Pharmacology
    Article Open access 06 March 2023
  14. Cardiovascular responses of adult male Sprague–Dawley rats following acute organophosphate intoxication and post-exposure treatment with midazolam with or without allopregnanolone

    Recent experimental evidence suggests combined treatment with midazolam and allopregnanolone is more effective than midazolam alone in terminating...

    Shiyue Pan, Donald A. Bruun, ... Chao-Yin Chen in Archives of Toxicology
    Article Open access 02 February 2024
  15. Cardiovascular Diseases and Periodontitis

    Periodontitis is a chronic inflammatory disease of the tooth-supporting connective tissue and alveolar bone that is initiated by a bacterial biofilm...
    Peter Riis Hansen, Palle Holmstrup in Periodontitis
    Chapter 2022
  16. Beyond steps per day: other measures of real-world walking after stroke related to cardiovascular risk

    Background

    Significant variability exists in how real-world walking has been measured in prior studies in individuals with stroke and it is unknown...

    Allison Miller, Zachary Collier, Darcy S. Reisman in Journal of NeuroEngineering and Rehabilitation
    Article Open access 14 October 2022
  17. Development and validation of a new algorithm for improved cardiovascular risk prediction

    QRISK algorithms use data from millions of people to help clinicians identify individuals at high risk of cardiovascular disease (CVD). Here, we...

    Julia Hippisley-Cox, Carol A. C. Coupland, ... Keith M. Channon in Nature Medicine
    Article Open access 18 April 2024
  18. Causal roles and clinical utility of cardiovascular proteins in colorectal cancer risk: a multi-modal study integrating mendelian randomization, expression profiling, and survival analysis

    Purpose

    This comprehensive investigation delved into the intricate causal interplay existing between cardiovascular-related plasma proteins and the...

    Chenlei Tan, Yanhua Li, ... Xuebao Zheng in BMC Medical Genomics
    Article Open access 22 May 2024
  19. The Use of Microbial Modifying Therapies to Prevent Psoriasis Exacerbation and Associated Cardiovascular Comorbidity

    Psoriasis has emerged as a systemic disease characterized by skin and joint manifestations as well as systemic inflammation and cardiovascular...

    Eva Reali, Cristiana Caliceti, ... Paola Rizzo in Inflammation
    Article Open access 13 November 2023
  20. Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis

    Tirzepatide is a novel, once weekly, dual GIP/GLP-1 receptor agonist and is under development for the treatment of type 2 diabetes (T2D) and obesity....

    Naveed Sattar, Darren K. McGuire, ... Sophia Zoungas in Nature Medicine
    Article Open access 24 February 2022
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