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Eomes expression identifies the early bone marrow precursor to classical NK cells
Natural killer (NK) cells traffic through the blood and mount cytolytic and interferon-γ (IFNγ)-focused responses to intracellular pathogens and...
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Detection of Antigen Presentation by Murine Bone Marrow–Derived Dendritic Cells After Treatment with Nanoparticles
Nanoparticles are frequently considered in vaccine applications due to their ability to co-deliver multiple antigens and adjuvants to... -
Effect of Glycodelin on the Cytokine Profile of Rats during Allogeneic Bone Marrow Cell Transplantation
The protein glycodelin (PP14, PAEP) is associated with pregnancy and exhibits pronounced immunotropic properties. We studied the effect of glycodelin...
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Radiomics analysis of bone marrow biopsy locations in [18F]FDG PET/CT images for measurable residual disease assessment in multiple myeloma
The combination of visual assessment of whole body [ 18 F]FDG PET images and evaluation of bone marrow samples by Multiparameter Flow Cytometry (MFC)...
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Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels
It remains unclear how immune cells from skull bone marrow niches are recruited to the meninges. Here we report that cerebrospinal fluid (CSF)...
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Uncovering the cellular and omics characteristics of natural killer cells in the bone marrow microenvironment of patients with acute myeloid leukemia
BackgroundAcute myeloid leukemia (AML) is a highly heterogeneous hematologic malignancy and the most frequently acute leukemia of stem cell...
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Bone marrow adiposity during pathologic bone loss: molecular mechanisms underlying the cellular events
Bone marrow (BM) is a heterogeneous niche where bone marrow stromal cells (BMSCs), osteoblasts, osteoclasts, adipocytes, hematopoietic cells, and...
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ILC Differentiation from Progenitors in the Bone Marrow
Innate lymphoid cells (ILCs) are a family of immune cells that possess similar functions as T cells. We review steps of central ILC development in... -
The relationship between the radiation dose of pelvic-bone marrow and lymphocytic toxicity in concurrent chemoradiotherapy for cervical cancer
ObjectiveThe purpose of this study is to verify the correlation between medium and low radiation doses of the pelvic-bone marrow and the incidence of...
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The role of bone marrow adipocytes in cancer progression: the impact of obesity
Bone marrow adipose tissues (BMATs) and their main cellular component, bone marrow adipocytes (BMAds), are found within the bone marrow (BM), which...
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Global characterization of megakaryocytes in bone marrow, peripheral blood, and cord blood by single-cell RNA sequencing
Megakaryocytes (MK) are mainly derived from bone marrow and are mainly involved in platelet production. Studies have shown that MK derived from bone...
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Bone Marrow-Derived Mononuclear Cells in the Treatment of Neurological Diseases: Knowns and Unknowns
AbstractBone marrow-derived mononuclear cells (BMMNCs) have been used for decades in preclinical and clinical studies to treat various neurological...
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Functional MRI radiomics-based assessment of pelvic bone marrow changes after concurrent chemoradiotherapy for cervical cancer
ObjectivesTo quantify the dose-response relationship of changes in pelvic bone marrow (PBM) functional MR radiomic features (RF) during concurrent...
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An atlas of the bone marrow bone proteome in patients with dysproteinemias
Multiple myeloma (MM) bone disease is a significant cause of morbidity but there is a paucity of data on the impact of malignant plasma cells on...
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Antigen-Specific Stimulation of CD8+ T Cells by Murine Bone Marrow–Derived Dendritic Cells After Treatment with Nanoparticles
The assessment of antigen presentation by dendritic cells and subsequent antigen-dependent activation of T lymphocytes is a critical step underlying... -
Effects of fine particulate matter on bone marrow-conserved hematopoietic and mesenchymal stem cells: a systematic review
The harmful effects of fine particulate matter ≤2.5 µm in size (PM 2.5 ) on human health have received considerable attention. However, while the...
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Changes in the Number of Mesenchymal Stem Cells in Bone Marrow at Different Periods after In Vivo Exposure of the Bone Marrow to Local Infrared Laser Radiation
We determined optimal parameters of bone marrow (BM) irradiation in vivo for rapid increase in the number of mesenchymal stem cells (MSC) at the...
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Characterization of the biological and transcriptomic landscapes of bone marrow-derived mesenchymal stem cells in patients with multiple myeloma
BackgroundMesenchymal stem/stromal cells (MSCs) have been acknowledged as the most important stromal cells in the bone marrow (BM) microenvironment...