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Malaria is a cause of iron deficiency in African children
Malaria and iron deficiency (ID) are common and interrelated public health problems in African children. Observational data suggest that interrupting...
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Monkeypox: disease epidemiology, host immunity and clinical interventions
Monkeypox virus (MPXV), which causes disease in humans, has for many years been restricted to the African continent, with only a handful of sporadic...
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First molecular detection of Sarcocystis suihominis in a domestic pig of Nigeria
Sarcocystis are Apicomplexan protozoa with a dixenous life cycle that includes a predator and a prey as definitive and intermediate hosts,...
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Pseudodactylogyrus anguillae (Yin & Sproston, 1948) from the giant mottled eel Anguilla marmorata Quoy & Gaimard, 1824, in the Phongolo River, South Africa: an invader on the African continent
The global invasive anguillid gill parasite Pseudodactylogyrus anguillae (Yin and Sproston, 1948) has only recently been documented from eels in...
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A community approach of pathogens and their arthropod vectors (ticks and fleas) in dogs of African Sub-Sahara
BackgroundArthropod-borne pathogens and their vectors are present throughout Africa. They have been well-studied in livestock of sub-Saharan Africa,...
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Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions
Early identification of genetic risk factors for complex diseases can enable timely interventions and prevent serious outcomes, including mortality....
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Progress in Research on African Trypanosomes: Highlights from an Exceptional Decade
In the late nineteenth century, Trypanosoma brucei was discovered as the parasitic protist responsible for Human African Trypanosomiasis (HAT), also... -
Frequency and spectrum of mutations across 94 cancer predisposition genes in African American women with invasive breast cancer
African American women are at increased risk of being diagnosed at a young age and/or with triple negative breast cancer, both factors which are...
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Tick-borne pathogens and body condition of cattle in smallholder rural livestock production systems in East and West Africa
BackgroundThe majority of the African population lives in rural areas where they heavily depend on crop and livestock production for their...
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Empowering newborn screening programs in African countries through establishment of an international collaborative effort
In an effort to explore new knowledge and to develop meaningful collaborations for improving child health, the First Pan African Workshop on Newborn...
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A community approach for pathogens and their arthropod vectors (ticks and fleas) in cats of sub-Saharan Africa
BackgroundArthropod-borne pathogens and their vectors are present throughout Africa. They have been well studied in livestock of sub-Saharan Africa,...
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An atlas of tsetse and animal African trypanosomiasis in Zimbabwe
BackgroundIn the 1980s and 1990s, great strides were taken towards the elimination of tsetse and animal African trypanosomiasis (AAT) in Zimbabwe....
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Biogeographical survey of soil microbiomes across sub-Saharan Africa: structure, drivers, and predicted climate-driven changes
BackgroundTop-soil microbiomes make a vital contribution to the Earth’s ecology and harbor an extraordinarily high biodiversity. They are also key...
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Evaluating the promise of inclusion of African ancestry populations in genomics
The lack of representation of diverse ancestral backgrounds in genomic research is well-known, and the resultant scientific and ethical limitations...
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Africa’s Response to Pandemics
Disease origins in Africa are often considered mysterious and tied to supernatural courses. Thus, most treatmentsTreatment follow an all-inclusive... -
A Southeast Asian origin for present-day non-African human Y chromosomes
The genomes of present-day humans outside Africa originated almost entirely from a single out-migration ~ 50,000–70,000 years ago, followed by...
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Design and validation of a laboratory-developed diagnostic assay for monkeypox virus
Mpox is a viral zoonosis with endemic circulation in animals and humans in some West and Central African countries. The disease was imported a few...
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Socio-economic and demographic impacts on the full awareness of the methods for controlling/preventing the spread of COVID-19 among social media users in some African countries at the onset of the pandemic
ObjectiveIn Africa, most countries continue to battle COVID-19 with cases of newly infected still being recorded. In this note, we investigate how...
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The potential of anti-malarial compounds derived from African medicinal plants: a review of pharmacological evaluations from 2013 to 2019
BackgroundAfrican Traditional Medicine (ATM) is used for the healthcare of about 80% of the rural populations of the continent of Africa. The...