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Serological responses of patients with nasopharyngeal carcinoma to an N-terminal Epstein-Barr virus DNA polymerase protein expressed in prokaryotic cells
A 1.7-kb cDNA clone, pGEM-cDP, was isolated from a cDNA library of IUdR-induced p3HR1 cells. It contains the upstream nucleotide sequence of the...
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Recent Advances in Recombinant Vaccines for Viral and Parasitic Diseases
The rapid development of recombinant DNA technology has enhanced the prospects for improved vaccines in a number of areas. The ability to express...
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Protective immunity of Hantaan virus nucleocapsid and envelope protein studied using baculovirus-expressed proteins
Recombinant Hantaan virus nucleocapsid protein (rNP) and recombinant envelope (rEnv) proteins were prepared using a baculovirus expression system to...
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The structural and functional organization of the autographa californica nuclear polyhedrosis virus genome
Baculoviruses are used as biological control agents of insect pests in agriculture and forestry. The multiple-nucleocapsid nuclear polyhedrosis virus...
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Neurofibromatosis type 1 gene product (neurofibromin) associates with microtubules
The neurofibromatosis type 1 (NF1) gene was recently identified by positional cloning and found to encode a protein with structural and functional...
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Fine map** of HIV-1 Nef-epitopes by monoclonal antibodies
A panel of newly isolated murine monoclonal antibodies is described which are specific for the Nef protein of the human immunodeficiency virus type 1...
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Studies on processing, particle formation, and immunogenicity of the HIV-1gag gene product: a possible component of a HIV vaccine
Antigens in a particulate conformation were shown to be highly immunogenic in mammals. For this reason, the particle forming capacity of derivatives...
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Polymerase Chain Reaction Diagnosis of Human Parvovirus B19
Polymerase chain reaction (PCR) is being widely applied in virological laboratories, although it is not yet a routine technique. It has been used for...
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Immunoselection of recombinant baculoviruses expressing high levels of biologically active herpes simplex virus type 1 glycoprotein D
The DNA sequence encoding the complete herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) was inserted into a baculovirus transfer vector under...
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Interleukin-3
Interleukin-3 (IL-3) is one of a large and growing group of growth factors which support the proliferation and differentiation of hematopoietic...
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Biotechnology of β-adrenergic receptors
The emergence of Biotechnology has provided pharmacologists with a variety of methods for investigating the structure, the function, and the...
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Infected cell specific protein and viral DNA synthesis in productive and abortive infections ofSpodoptera frugiperda nuclear polyhedrosis virus
This study examines viral protein and DNA synthesis in Spodoptera frugiperda multicapsid nuclear polyhedrosis virus (SfMNPV) infections of S. frugiperda ...
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Insect Neuroendocrinology: Its Past; its Present; Future Opportunities
Insects played a major historical role as experimental animals to provide some of the first evidence concerning endocrine functions by the nervous...
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Interleukin-3
Interleukin-3 (IL-3) is one of a large and growing group of growth factors which support the proliferation and differentiation of hematopoietic...
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Antigens and Adjuvants for a New Generation of Vaccines
More than a decade has passed since vaccination made possible the global eradication of smallpox. Vaccination has also been remarkably successful in...