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The role of circadian clock pathways in viral replication
The daily oscillations of bi ological and behavioural processes are controlled by the circadian clock circuitry that drives the physiology of the...
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The current landscape of coronavirus-host protein–protein interactions
In less than 20 years, three deadly coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2, have emerged in human population causing hundreds to hundreds...
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Identification of G-quadruplex DNA sequences in SARS-CoV2
G-quadruplex structure or Putative Quadruplex Sequences (PQSs) are abundant in human, microbial, DNA, or RNA viral genomes. These sequences in RNA...
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Integrative microbiomics in bronchiectasis exacerbations
Bronchiectasis, a progressive chronic airway disease, is characterized by microbial colonization and infection. We present an approach to the...
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Network machine learning maps phytochemically rich “Hyperfoods” to fight COVID-19
In this paper, we introduce a network machine learning method to identify potential bioactive anti-COVID-19 molecules in foods based on their...
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SARS-CoV-2 viral protein Nsp2 stimulates translation under normal and hypoxic conditions
When viruses like SARS-CoV-2 infect cells, they reprogram the repertoire of cellular and viral transcripts that are being translated to optimize...
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An auto-antibody identified from phenotypic directed screening platform shows host immunity against EV-A71 infection
BackgroundEnterovirus A71 (EV-A71) is a neurotropic virus which may cause severe neural complications, especially in infants and children. The...
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Nucleoprotein (P40) Binding to 5HT2C Receptors (5HT2CR) is the Key Point in the Pathogenesis of BoDV-1-Infected Hosts
Nucleoprotein (P40) is one of the most important proteins of Borna disease virus 1 (BoDV-1), but which proteins it would bind to in the pathogenesis...
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Proteomics Profiling of Host Cell Response via Protein Expression and Phosphorylation upon Dengue Virus Infection
Dengue virus (DENV) infection is a worldwide public health threat. To date, the knowledge about the pathogenesis and progression of DENV infection is...
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Structural aspects of hepatitis E virus
Hepatitis E virus (HEV) is a leading cause of acute hepatitis worldwide. Hepatitis E is an enterically transmitted zoonotic disease that causes large...
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Roles of host mitochondria in the development of COVID-19 pathology: Could mitochondria be a potential therapeutic target?
The recent emergence of severe acute respiratory syndrome-Corona Virus 2 (SARS-CoV-2) in late 2019 and its spread worldwide caused an acute pandemic...
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The interactions of ZDHHC5/GOLGA7 with SARS-CoV-2 spike (S) protein and their effects on S protein’s subcellular localization, palmitoylation and pseudovirus entry
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein determines virus entry and the palmitoylation of S protein...
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Predicting the response of the dental pulp to SARS-CoV2 infection: a transcriptome-wide effect cross-analysis
Pulpitis, inflammation of the dental pulp, is a disease that often necessitates emergency dental care. While pulpitis is considered to be a microbial...
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HIV-2/SIV Vpx antagonises NF-κB activation by targeting p65
BackgroundThe NF-κB family of transcription factors and associated signalling pathways are abundant and ubiquitous in human immune responses....
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Advances in high-throughput methods for the identification of virus receptors
Viruses have evolved many mechanisms to invade host cells and establish successful infections. The interaction between viral attachment proteins and...
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Fluorescent Light Opening New Horizons
In this final Chapter we try to evaluate the most rapidly progressing application areas of fluorescence sensing technologies and to make prognosis...
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A Sco** Review of Research on the Unfolding Human Microbiome Landscape in the Metagenomics Era
Research on the microbiome is motivated by an urge to understand the underlying causes of disease and the microbiota’s role in both causing and...
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Liver in infections: a single-cell and spatial transcriptomics perspective
The liver is an immune organ that plays a vital role in the detection, capture, and clearance of pathogens and foreign antigens that invade the human...
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Ebola Virus: Overview, Genome Analysis and Its Antagonists
Ebola is an inexorable, negative-sense, single-strand, non-segmented RNARibonucleic acid (RNA) virus which rapidly develops alterations through...
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Recent Advances in the Treatment of Parasitic Diseases: Current Status and Future
As per World Health Organization (WHO), parasitic diseases significantly threaten global health. Diminishing boundaries have contributed to its...