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1. Curcumin Promotes the Expression of IL-35 by Regulating Regulatory T Cell Differentiation and Restrains Uncontrolled Inflammation and Lung Injury in Mice

   Interleukin (IL)-35, which has an anti-inflammatory role in acute respiratory distress syndrome (ARDS)/acute lung injury (ALI), is relatively...

   Yan-qing Chen, Yu-sen Chai, ... Fang Xu in Inflammation

   Article 14 June 2020
   

2. TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice

   Background

   Neuroinflammation is an important host defense response to secondary brain injury after intracerebral hemorrhage (ICH). Triggering receptor...

   Shengpan Chen, Jianhua Peng, ... Hongqi Zhang in Journal of Neuroinflammation

   Article Open access 28 May 2020
   

3. Lung Transplantation under a Janus Kinase Inhibitor in Three Patients with SAVI Syndrome

   Stimulator of interferon genes (STING)-associated vasculopathy with onset in infancy (SAVI) is a very rare autoinflammatory disease related to STING1 ...

   Kenza Rhzioual Berrada, Alexandre Belot, ... Philippe Reix in Journal of Clinical Immunology

   Article 10 October 2023
   

4. Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain

   The glial environment influences neurological disease progression, yet much of our knowledge still relies on preclinical animal studies, especially...

   Swetlana Sirko, Christian Schichor, ... Magdalena Götz in Nature Medicine

   Article Open access 08 December 2023
   

5. Association Between Regular Blood Pressure Monitoring and the Risk of Intracranial Aneurysm Rupture: a Multicenter Retrospective Study with Propensity Score Matching

   Although hypertension is a known risk factor for intracranial aneurysm rupture, the benefit of the management of blood pressure in reducing the...

   ** Zhong, Zhiwen Lu, ... Qinghai Huang in Translational Stroke Research

   Article 21 March 2022
   

6. GPR84 regulates pulmonary inflammation by modulating neutrophil functions

   Acute lung injury (ALI) is an acute, progressive hypoxic respiratory failure that could develop into acute respiratory distress syndrome (ARDS) with...

   Si-wei Wang, Qing Zhang, ... **n **e in Acta Pharmacologica Sinica

   Article Open access 04 April 2023
   

7. Different intensity of autophagy regulate interleukin-33 to control the uncontrolled inflammation of acute lung injury

   Objectives

   Cytokines participate in the progression of acute respiratory distress syndrome (ARDS), and uncontrolled inflammation is a central issue of...

   Ming Lei, Chuan-jiang Wang, ... Fang Xu in Inflammation Research

   Article 30 May 2019
   

8. Levothyroxine dosages during pregnancy among hypothyroid women. An experience from a tertiary care center of Karachi, Pakistan, based on data from Maternal Hypothyroidism on Pregnancy Outcomes Study (MHPO-5)

   Objectives

   The dosage of levothyroxine (LT4) during pregnancy differs among different ethnic groups worldwide. These differences are due to variations...

   Zareen Kiran, Wardah Khalid, ... Najmul Islam in BMC Research Notes

   Article Open access 07 March 2022

9. Exploring the Role of Mesenchymal Stem Cell–Derived Exosomes in Diabetic and Chemotherapy-Induced Peripheral Neuropathy

   Diabetic and chemotherapy-induced peripheral neuropathies are known for long-term complications that are associated with uncontrolled hyperglycemia...

   Lamiaa A. Ahmed, Khaled F. Al-Massri in Molecular Neurobiology

   Article Open access 22 January 2024
   

10. The influence of unexpected early termination of intravenous rt-PA treatment on clinical outcome in acute ischemic stroke patients

    Introduction

    This study aimed to explore the impact of unexpected early termination during intravenous thrombolysis on clinical prognosis in patients...

    Tingting Qu, Yiwen Bao, ... Dongya Huang in Acta Neurologica Belgica

    Article 02 August 2022
    

11. Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage

    Background

    Neuroinflammation is closely associated with the poor prognosis in subarachnoid hemorrhage (SAH) patients. This study was aimed to...

    Yucong Peng, Jianfeng Zhuang, ... Gao Chen in Journal of Neuroinflammation

    Article Open access 25 May 2020
    

12. Efficacy and Safety of Recombinant Human Prourokinase in Acute Ischemic Stroke: A Phase IIa Randomized Clinical Trial

    Recombinant human prourokinase (rhPro-UK) is a novel thrombolytic that has been approved to treat patients with acute myocardial infarction. However,...

    Haiqing Song, Yuan Wang, ... Yu** Wang in Translational Stroke Research

    Article 03 May 2022
    

13. Modeling and simulation of the modified Rankin Scale and National Institutes of Health Stroke Scale neurological endpoints in intracerebral hemorrhage

    Intracerebral hemorrhage (ICH) is a form of stroke characterized by uncontrolled bleeding into the parenchyma of the brain. There is no approved...

    Rik Schoemaker, Satyaprakash Nayak, ... Thorsten Steiner in Journal of Pharmacokinetics and Pharmacodynamics

    Article 29 August 2019
    

14. Fatal adverse events of rivaroxaban combined with aspirin: an analysis using data from VigiBase

    Purpose

    The aim of this study was to analyze the clinical characteristics of fatal adverse events (AEs) of rivaroxaban combined with aspirin and to...

    Qingxia Zhang, Qian Ding, ... Qun-Ying Yue in European Journal of Clinical Pharmacology

    Article Open access 01 July 2022

15. Utility of A₂L₂ score in acute ischemic stroke patient triage: the “H.uni” experience

    Background and aims

    Two or more National Institutes of Health Stroke Scale (NIHSS) points on each motor items (A ₂ L ₂ score) have shown good accuracy...

    Pasquale Scoppettuolo, Jean-Marc Raymackers, ... André Peeters in Acta Neurologica Belgica

    Article 27 June 2024
    

16. Comparing Transcranial Direct Current Stimulation (tDCS) with Other Non-Invasive Brain Stimulation (NIBS) in the Treatment of Alzheimer’s Disease: A Literature Review

    Purpose

    Identifying the effective treatments for diseases has been a critical issue in daily clinical practice, especially for Alzheimer’s dementia...

    Carol Sheei-Meei Wang, Wei-Hung Chang, ... Kuo-Sheng Cheng in Journal of Medical and Biological Engineering

    Article Open access 23 August 2023
    

17. Evaluation of AAV Capsids and Delivery Approaches for Hereditary Hemorrhagic Telangiectasia Gene Therapy

    Nosebleeds and intracranial hemorrhage from brain arteriovenous malformations (bAVMs) are among the most devastating symptoms of patients with...

    Alka Yadav, Rich Liang, ... Hua Su in Translational Stroke Research

    Article 08 July 2024
    

18. Fn14 exacerbates acute lung injury by activating the NLRP3 inflammasome in mice

    Background

    Uncontrolled inflammation is an important factor in the occurrence and development of acute lung injury (ALI). Fibroblast growth...

    **n-**n Guan, Hui-Hui Yang, ... Cha-**ang Guan in Molecular Medicine

    Article Open access 30 July 2022
    

19. Incomplete Knockdown of MyD88 Inhibits LPS-Induced Lung Injury and Lung Fibrosis in a Mouse Model

    Acute lung injury (ALI) is a life-threatening disorder stemmed mainly from an uncontrolled inflammatory response. Lipopolysaccharide (LPS) is...

    Hui Fan, Yanni Wang, ... Guozhong Chen in Inflammation

    Article 22 August 2023
    

20. Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database

    Background

    The management of uncontrolled severe asthma has greatly improved since the advent of novel biologic therapies. Up to August 2022, five...

    Paola Maria Cutroneo, Elena Arzenton, ... Gianluca Trifirò in BioDrugs

    Article Open access 15 March 2024