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A latent pathogen infection classification system that would significantly increase healthcare safety
Most viral, bacterial, fungal, and protozoan pathogens can cause latent infections. Latent pathogens can be reactivated from any intentional medical...
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Pathogenesis and Immune Response in T. cruzi Infection: Quest for Natural Compound-Based Drugs
Trypanosoma cruzi, a pathogenic protozoan, is known to cause chronic and systemic infection in humans called as Chagas disease, which imposes serious...
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Novel Diagnostic Methods for Emerging Respiratory Viral Infection
Since the global emergence of COVID-19, viral respiratory infections have become a major cause for concern for people due to an increase in the basic...
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Bioluminescence Imaging, a Powerful Tool to Assess Fungal Burden in Live Mouse Models of Infection
Aspergillus fumigatus and Cryptococcus neoformans species infections are two of the most common life-threatening fungal infections in the...
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Predicting the primary infection source of Escherichia coli bacteremia using virulence-associated genes
PurposeTo investigate the role of E. coli virulence-associated genes (VAGs) in predicting urinary tract infection (UTI) as the source of bacteremia...
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Defining the balance between optimal immunity and immunopathology in influenza virus infection
Influenza A viruses remain a global threat to human health, with continued pandemic potential. In this Review, we discuss our current understanding...
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Prevalence of active cytomegalovirus infection at diagnosis of ovarian cancer and during chemotherapy and subsequent changes in cognitive functioning
PurposeOne of the most frequently reported effects of cancer and its treatments is cancer-related cognitive impairment (CRCI). Viral infections may...
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Reactivation of occult hepatitis B virus infection in a renal transplant recipient
We report a case of hepatitis B virus (HBV) reactivation in a renal transplant recipient. Reactivation manifested as an occult infection with...
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The opposing effect of acute and chronic Toxoplasma gondii infection on tumor development
BackgroundThe interplay between Toxoplasma gondii infection and tumor development is intriguing and not yet fully understood. Some studies showed...
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HIV-1 infection of renal epithelial cells: 30 years of evidence from transgenic animal models, human studies and in vitro experiments
Although antiretroviral therapy (ART) has increased life expectancy in people with HIV-1 (PWH), acute and chronic kidney disease remain common in...
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Review on infection control strategies to minimize outbreaks of the emerging pathogen Elizabethkingia anophelis
BackgroundElizabethkingia anophelis is a multi-drug resistant emerging opportunistic pathogen with a high mortality rate, causing...
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Expanded clinical-grade NK cells exhibit stronger effects than primary NK cells against HCMV infection
Cytomegalovirus (CMV) reactivation remains a common complication and leads to high mortality in patients who undergo allogeneic hematopoietic stem...
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Recurrent Clostridioides difficile Infection: Current Clinical Management and Microbiome-Based Therapies
Clostridioides difficile is one of the most important causes of healthcare-associated diarrhea. The high incidence and recurrence rates of C. difficile ...
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Prevention of ICU-acquired infection with decontamination regimen in immunocompromised patients: a pre/post observational study
PurposeAlthough the proportion of immunocompromised patients admitted to the ICU is increasing, data regarding specific management, including...
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A case of successful contribution of therapeutic drug monitoring of valganciclovir as the prophylaxis against cytomegalovirus infection in a lung transplant recipient
BackgroundGanciclovir and its prodrug, valganciclovir, are first-line agents for cytomegalovirus infection prophylaxis after lung transplantation....
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Toxoplasmosis and cytomegalovirus infection and their role in Egyptian autistic children
Autism is a neurodevelopmental disorder with a significantly increased incidence rate across the world over the past few years. Toxoplasmosis and...
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Regulated cell death pathways and their roles in homeostasis, infection, inflammation, and tumorigenesis
Pyroptosis, apoptosis, necroptosis, and ferroptosis, which are the most well-studied regulated cell death (RCD) pathways, contribute to the clearance...
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Tryptophan catabolism via the kynurenine pathway regulates infection and inflammation: from mechanisms to biomarkers and therapies
Backgroundl -Tryptophan ( l -Trp), an essential amino acid, is the only amino acid whose level is regulated specifically by immune signals. Most...
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Altered gastrointestinal tract structure and microbiome following cerebral malaria infection
Cerebral malaria (CM) is the most severe form of malaria with the highest mortality rate and can result in life-long neurological deficits and...
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SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immune responses and infection outcomes were evaluated in 2,686 patients with varying...
