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Impact of modified short-term fasting and its combination with a fasting supportive diet during chemotherapy on the incidence and severity of chemotherapy-induced toxicities in cancer patients - a controlled cross-over pilot study
BackgroundThis pilot trial aimed to investigate whether modified short-term fasting (mSTF) reduces the incidence of chemotherapy-induced toxicities...
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Fasting-Mimicking-Diet does not reduce skeletal muscle function in healthy young adults: a randomized control trial
PurposeThe aim of this study was to evaluate the short- and long-term effects of the Fasting-Mimicking-Diet (FMD) intervention on neuromuscular...
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Evaluation of short-term epigenetic age fluctuation
Considerable effort has been spent on lowering and maintaining the epigenetic age. However, the extent to which epigenetic age fluctuates under...
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Short-term cocoa bioflavanol supplementation does not improve cold-induced vasodilation in young healthy adults
PurposeCold-induced vasodilation (CIVD) is an oscillatory rise in blood flow to glabrous skin that occurs in cold-exposed extremities. Dietary...
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Carotid Body Resection Prevents Short-Term Spatial Memory Decline in Prediabetic Rats Without Changing Insulin Signaling in the Hippocampus and Prefrontal Cortex
Individuals who develop type 2 diabetes (T2D) at an early age are at higher risk of develo** neurodegenerative disorders such as Alzheimer’s and...
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Impact of a short-term nitrate and citrulline co-supplementation on sport performance in elite rowers: a randomized, double-blind, placebo-controlled crossover trial
PurposeCitrulline (CIT) and beetroot extract (BR) have separately shown benefits in rowing performance-related outcomes. However, effects of combined...
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Benefits, mechanisms, and risks of intermittent fasting in metabolic syndrome and type 2 diabetes
One of the emergent nutritional strategies for improving multiple features of cardiometabolic diseases is the practice of intermittent fasting (IF),...
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Effects of long-term fasting and confinement on the cardiovascular activity
Fasting has been demonstrated to improve health and slow aging in human and other species; however, its impact on the human body in the confined...
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Does ramadan fasting affect the therapeutic and clinical outcomes of warfarin? a systematic review and meta-analysis
BackgroundWarfarin's therapeutic effect is affected by many factors, including diet modifications. The impact of Ramadan fasting on warfarin is...
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Short-term starvation synergistically enhances cytotoxicity of Niraparib via Akt/mTOR signaling pathway in ovarian cancer therapy
BackgroundShort-term starvation (STS) has gradually been confirmed as a treatment method that synergistically enhances the effect of chemotherapy on...
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Weight-gain independent effect of mirtazapine on fasting plasma lipids in healthy men
Treatment with mirtazapine, a widely prescribed antidepressant, has been linked to weight gain and dyslipidemia. Whether dyslipidemia occurs...
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Carotid intima media thickness measurements coupled with stroke severity strongly predict short-term outcome in patients with acute ischemic stroke: a machine learning study
Acute ischemic stroke (IS) is one of the leading causes of morbidity, functional disability and mortality worldwide. The objective was to evaluate IS...
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Intermittent fasting reduces neuroinflammation in intracerebral hemorrhage through the Sirt3/Nrf2/HO-1 pathway
BackgroundInflammation contributes to the poor prognosis of intracerebral hemorrhage (ICH). Intermittent fasting (IF) has been shown to be protective...
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Effects of short-term fasting on cancer treatment
Growing preclinical evidence shows that short-term fasting (STF) protects from toxicity while enhancing the efficacy of a variety of chemotherapeutic...
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Short-term survival and safety of apatinib combined with oxaliplatin and S-1 in the conversion therapy of unresectable gastric cancer
BackgroundWe conducted a single-arm phase II trial to investigate the short-term efficacy and safety of apatinib combined with oxaliplatin and S-1 in...
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Do Fasting, CR and FMD Improve the Chemotherapy Response, Reduce Off-Target Toxicities and Enhance Antitumour Immunity? Illusion or Clinical Reality?
Besides the great strides of efforts made towards understanding the effect of fasting, calorie restriction (CR) and fasting-mimicking diet (FMD), yet...
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Short-term calorie restriction enhances DNA repair by non-homologous end joining in mice
Calorie restriction (CR) improves health, reduces cancer incidence and extends lifespan in multiple organisms including mice. CR was shown to enhance...
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The Impact of Fasting on Major Metabolic Pathways of Macronutrients and Pharmacokinetics Steps of Drugs
In this review, we have investigated how fasting promotes an adaptive cross-talk between different hormones and metabolic pathways to supply and meet...
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Short-term glycemic variability and hemorrhagic transformation after successful endovascular thrombectomy
BackgroundGlycemic variability (GV) is a risk factor for poor outcomes after ischemic stroke. However, its effect on hemorrhagic transformation after...