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Prefrontal allopregnanolone synergizes with D1 receptor activation to disrupt sensorimotor gating in male Sprague-Dawley rats
Abstract RationaleThe prepulse inhibition (PPI) of the startle reflex is the best-established index of sensorimotor gating. We documented that the...
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Oral probiotic therapy improves motor function in a rodent model of sensorimotor stroke
Ischemic stroke is a debilitating neurological disease with few effective therapeutics. Previous work has shown that oral probiotic treatment prior...
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Schema formation in a neural population subspace underlies learning-to-learn in flexible sensorimotor problem-solving
Learning-to-learn, a progressive speedup of learning while solving a series of similar problems, represents a core process of knowledge acquisition...
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Dissociating the contributions of sensorimotor striatum to automatic and visually guided motor sequences
The ability to sequence movements in response to new task demands enables rich and adaptive behavior. However, such flexibility is computationally...
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Ventromedial Thalamus-Projecting DCN Neurons Modulate Associative Sensorimotor Responses in Mice
The deep cerebellar nuclei (DCN) integrate various inputs to the cerebellum and form the final cerebellar outputs critical for associative...
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Activity in primate visual cortex is minimally driven by spontaneous movements
Organisms process sensory information in the context of their own moving bodies, an idea referred to as embodiment. This idea is important for...
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Reactivity of EEG Sensorimotor Rhythms on Observation of Pro- and Antisocial Actions in Young Children
Moral development is necessary for the successful socialization of the individual. The mirror neuron system plays an important role in forming...
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Complementary task representations in hippocampus and prefrontal cortex for generalizing the structure of problems
Humans and other animals effortlessly generalize prior knowledge to solve novel problems, by abstracting common structure and map** it onto new...
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Effects of the Mirror Box Illusion on EEG Sensorimotor Rhythms in Voluntary and Involuntary Finger Movements
Rhythmic sensorimotor EEG activity patterns were studied in 25 subjects in experiments with a mirror box illusion of movement. In the experiments,...
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Cerebral organoids transplantation repairs infarcted cortex and restores impaired function after stroke
Stroke usually causes prolonged or lifelong disability, owing to the permanent loss of infarcted tissue. Although a variety of stem cell...
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Effect of long-term paired associative stimulation on the modulation of cortical sensorimotor oscillations after spinal cord injury
Study designA prospective interventional case series.
ObjectivesTo explore changes in the modulation of cortical sensorimotor oscillations after...
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Is song processing distinct and special in the auditory cortex?
Is the singing voice processed distinctively in the human brain? In this Perspective, we discuss what might distinguish song processing from speech...
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Tool use acquisition induces a multifunctional interference effect during object processing: evidence from the sensorimotor mu rhythm
A fundamental characteristic of human development is acquiring and accumulating tool use knowledge through observation and sensorimotor experience....
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Imaging Somatosensory Cortex in Rodents
The rodent somatosensory cortex has been investigated using a range of electrophysiological techniques, from intracellular recordings to...
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Dorsolateral Prefrontal Cortex
The prefrontal cortex is known to play an important role in planning and controlling a variety of cognitive functions and in organizing and...
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Sex-Specific Entorhinal Cortex Functional Connectivity in Cognitively Normal Older Adults with Amyloid-β Pathology
Sex and apolipoprotein E (APOE) genotype have been shown to influence the risk and progression of Alzheimer’s disease (AD). However, the impact of...
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Functional abnormality in the sensorimotor system attributed to NRXN1 variants in boys with attention deficit hyperactivity disorder
Impaired sensorimotor circuits have been suggested in Attention-deficit/hyperactivity disorder (ADHD). NRXN1 , highly expressed in cortex and...
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Impairment of the internal forward model and feedback mechanisms for vocal sensorimotor control in post-stroke aphasia: evidence from directional responses to altered auditory feedback
The present study examined opposing and following vocal responses to altered auditory feedback (AAF) to determine how damage to left-hemisphere brain...
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Pharmaco-toxicological effects of the novel tryptamine hallucinogen 5-MeO-MiPT on motor, sensorimotor, physiological, and cardiorespiratory parameters in mice—from a human poisoning case to the preclinical evidence
RationaleThe 5-methoxy-N-methyl-N-isopropyltryptamine (5-MeO-MiPT, known online as “Moxy”) is a new psychedelic tryptamine first identified on...
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Combination of Endothelin-1 (ET-1) and L-NAME to Induce Murine Focal Cortical Stroke with Persistent Sensorimotor Deficits
The endothelin-1 (ET-1)Endothelin-1 (ET-1) model of stroke Strokes involves Endothelin-1 (ET-1) the stereotactic injectionStereotactic injection of...