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Expression of SATB1 and SATB2 in the brain of bony fishes: what fish reveal about evolution
Satb1 and Satb2 belong to a family of homeodomain proteins with highly conserved functional and regulatory mechanisms and posttranslational...
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Phenotypic Analysis of Early Neurogenesis in a Mouse Chimeric Embryo and Stem Cell-Based Neuruloid Model
Analyzing the impact of genetic mutations on early neurogenesis of mammalian embryos in conventional mouse mutant models is laborious and...
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Applications of 3D organoids in toxicological studies: a comprehensive analysis based on bibliometrics and advances in toxicological mechanisms
A mechanism exploration is an important part of toxicological studies. However, traditional cell and animal models can no longer meet the current...
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Repetitive and zonal expression profiles of absorption-related genes in the gastrointestinal tract of ascidian Ciona intestinalis type A
Intestinal absorption is essential for heterotrophic bilaterians with a tubular gut. Although the fundamental features of the digestive system were...
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Molecular complexity and gene expression controlling cell turnover during a digestive cycle of carnivorous sponge Lycopodina hypogea
Lycopodina hypogea is a carnivorous sponge that tolerates laboratory husbandry very well. During a digestion cycle, performed without any digestive...
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Basic Principles of Mammalian CNS Systems: Nervous System Organization – Connectomics and the Connectome
As you read this textbook, you are learning about how Western science currently thinks about the nervous system and its biological functions. This...
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Comparative anatomy on the development of sperm transporting pathway between the testis and mesonephros
The male genital tract is diverse among vertebrates, but its development remains unclear, especially in the rete region. In this study, we...
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Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer
Thalamic neurons are distributed between different nuclear groups of the thalamic multinuclear complex; they develop topologically ordered specific...
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Advances in neural organoid systems and their application in neurotoxicity testing of environmental chemicals
Due to the complex structure and function of central nervous system (CNS), human CNS in vitro modeling is still a great challenge. Neurotoxicity...
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Cell-line dependency in cerebral organoid induction: cautionary observations in Alzheimer’s disease patient-derived induced pluripotent stem cells
The cerebral organoid (CO) model has been used in the study of various neurodegenerative diseases owing to its physiological implications. However,...
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The Importance of Regionalized Management of Medicine
The present book presents the new and international understanding, vision, and experience on regionalized management of medicine, including clinical...
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Riding the crest to get a head: neural crest evolution in vertebrates
In their seminal 1983 paper, Gans and Northcutt proposed that evolution of the vertebrate ‘new head’ was made possible by the advent of the neural...
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Dorsoventral Arrangement of Lateral Hypothalamus Populations in the Mouse Hypothalamus: a Prosomeric Genoarchitectonic Analysis
The lateral hypothalamus (LH) has a heterogeneous cytoarchitectonic organization that has not been elucidated in detail. In this work, we analyzed...
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The History of Rabies in Peru
Peru is a country with a diverse ecology that helped determine the historical distribution of rabies in the country: canine rabies in coastal urban...
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Mechanisms of Development
Many of the mechanisms underlying neural development are basically similar in vertebrates and invertebrates. Among vertebrates, popular species for...
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Prosomeric classification of retinorecipient centers: a new causal scenario
The retina is known to target many superficial areas in the brain. These have always been studied under the tenets of the classic columnar brain...
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Specification of the Cerebellar Territory
The cerebellar primordium develops dorsally at an intermediate anteroposterior (AP) level of the neural tube. Its size is modulated by the early...
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Intestinal immune compartmentalization: implications of tissue specific determinants in health and disease
The emerging concept of tissue specific immunity has opened the gates to new inquiries into what factors drive immune cell niche adaptation and the...
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Ocular and neural genes jointly regulate the visuospatial working memory in ADHD children
ObjectiveWorking memory (WM) deficits have frequently been linked to attention deficit hyperactivity disorder (ADHD). Despite previous studies...
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DjFARP Contributes to the Regeneration and Maintenance of the Brain through Activation of DjRac1 in Dugesia japonica
FERM, RhoGEF, and Pleckstrin domain protein (FARP) mediated RhoGTPase pathways are involved in diverse biological processes, such as neuronal...
