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1. Comprehensive Analysis of N6-Methyladenosine RNA Methylation Regulators in the Diagnosis and Subtype Classification of Rheumatoid Arthritis

   m6A modification is the most abundant mRNA modifications and plays an integral role in various biological processes in eukaryotes. However, the role...

   Shaoxiong Zhang, Shuo Sun, ... **guang Zhang in Biochemical Genetics

   Article 19 December 2023
   

2. METTL3-Mediated N6-Methyladenosine Modification of lncRNA D26496 Suppresses the Proliferation and Migration of Schwann Cells after Sciatic Nerve Injury

   Previous reports showed that LncRNA D26496 was downregulated and N6-methyladenosine (m6A) methyltransferase METTL3 was upregulated in sciatic nerve...

   **n He, Jia’nan Zhang, ... Dingjun Hao in Molecular Neurobiology

   Article 19 January 2023
   

3. N6-methyladenosine in myeloid cells: a novel regulatory factor for inflammation-related diseases

   N6-methyladenosine (m ⁶ A) is one of the most abundant epitranscriptomic modifications on eukaryotic mRNA. Evidence has highlighted that m ⁶ A is altered...

   ** Pang, Tong-dong Kuang, ... Kai Yin in Journal of Physiology and Biochemistry

   Article 30 December 2023
   

4. Insights into N6-methyladenosine and programmed cell death in cancer

   N6-methyladenosine (m6A) methylation, the most common form of internal RNA modification in eukaryotes, has gained increasing attention and become a...

   Li Liu, Hui Li, ... Ji Zhang in Molecular Cancer

   Article Open access 28 January 2022
   

5. N6-methyladenosine RNA modification (m6A) is of prognostic value in HPV-dependent vulvar squamous cell carcinoma

   Background

   Vulvar squamous cell carcinoma (VSCC) is an uncommon gynecologic malignancy but with an increasing incidence in recent years....

   Mateja Condic, Thore Thiesler, ... Damian J. Ralser in BMC Cancer

   Article Open access 01 September 2022
   

6. LncRNA FTO-IT1 promotes glycolysis and progression of hepatocellular carcinoma through modulating FTO-mediated N6-methyladenosine modification on GLUT1 and PKM2

   Background

   Long non-coding RNAs (LncRNAs) have been extensively studied to play essential roles in tumor progression. However, more in-depth studies...

   Fan Wang, Yuhang Hu, ... Gang Zhao in Journal of Experimental & Clinical Cancer Research

   Article Open access 16 October 2023
   

7. N6-methyladenosine methylation modification patterns reveal immune profiling in pancreatic adenocarcinoma

   Background

   Several studies have revealed that N6-methyladenosine (m6A) regulation is involved in various biological processes and cancer progression....

   Hao Xu, Lu Yin, ... Rujun Xu in Cancer Cell International

   Article Open access 23 May 2022
   

8. Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome

   Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder characterized by chronic low-grade inflammation. Previous studies have...

   Kailu Liu, ** He, ... **aowei Nie in Clinical Epigenetics

   Article Open access 13 May 2023
   

9. Mutual regulation between N6-methyladenosine (m6A) modification and circular RNAs in cancer: impacts on therapeutic resistance

   The resistance of tumor cells to therapy severely impairs the efficacy of treatment, leading to recurrence and metastasis of various cancers....

   Hong Lin, Yuxi Wang, ... Ting Wang in Molecular Cancer

   Article Open access 18 July 2022
   

10. Alteration of N6-methyladenosine epitranscriptome profile in lipopolysaccharide-induced mouse mesangial cells

    N6-Methyladenosine (m6A) is the most prevalent internal modification of messenger RNA (mRNA) in eukaryotes. The underlying molecular mechanisms of...

    Tao Liu, **ng **ng Zhuang, ... Jia Rong Gao in Naunyn-Schmiedeberg's Archives of Pharmacology

    Article 04 February 2022
    

11. N6-methyladenosine-modified circSLCO1B3 promotes intrahepatic cholangiocarcinoma progression via regulating HOXC8 and PD-L1

    Background

    Refractoriness to surgical resection and chemotherapy makes intrahepatic cholangiocarcinoma (ICC) a fatal cancer of the digestive system...

    **g Li, **aohong Xu, ... **nwei Han in Journal of Experimental & Clinical Cancer Research

    Article Open access 20 April 2024
    

12. N6-methyladenosine-dependent signalling in cancer progression and insights into cancer therapies

    The N6-methyladenosine (m6A) modification is a dynamic and reversible epigenetic modification, which is co-transcriptionally deposited by a...

    Fenghua Tan, Mengyao Zhao, ... Can Guo in Journal of Experimental & Clinical Cancer Research

    Article Open access 29 April 2021
    

13. N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease

    Background

    Synaptic degeneration occurs in the early stage of Alzheimer's disease (AD) before devastating symptoms, strongly correlated with cognitive...

    **ong Wang, Jiazhao **e, ... Liming Cheng in Translational Neurodegeneration

    Article Open access 28 November 2023
    

14. Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression

    Background

    UCA1 is frequently upregulated in a variety of cancers, including CRC, and it can play an oncogenic role by various mechanisms. However,...

    Rong-Zhang He, **g Jiang, ... Wan-**n Peng in Cancer Cell International

    Article Open access 22 November 2021
    

15. CCL3 secreted by hepatocytes promotes the metastasis of intrahepatic cholangiocarcinoma by VIRMA-mediated N6-methyladenosine (m⁶A) modification

    Background

    Intrahepatic cholangiocarcinoma (ICC) is a malignant disease characterized by onset occult, rapid progression, high relapse rate, and high...

    Shurui Zhou, Kege Yang, ... Yaqing Li in Journal of Translational Medicine

    Article Open access 23 January 2023
    

16. A novel peptide encoded by N6-methyladenosine modified circMAP3K4 prevents apoptosis in hepatocellular carcinoma

    Background

    Circular RNAs (circRNAs) regulate various biological activities and have been shown to play crucial roles in hepatocellular carcinoma (HCC)...

    **-Ling Duan, Wei Chen, ... Mu-Yan Cai in Molecular Cancer

    Article Open access 02 April 2022
    

17. The emerging role of RNA N6-methyladenosine methylation in breast cancer

    N6-methyladenosine (m6A) modification is the most prevalent internal mRNA modification and is involved in many biological processes in eukaryotes....

    Fangchao Zheng, Feng Du, ... Peng Yuan in Biomarker Research

    Article Open access 27 May 2021
    

18. RNA N6-methyladenosine: a new player in autophagy-mediated anti-cancer drug resistance

    Dysregulation of N6-methyladenosine (m6A) modification is associated with cancer development and progression. The m6A modification plays a crucial...

    Arumugam Paramasivam, Jayaseelan Vijayashree Priyadharsini in British Journal of Cancer

    Article 15 March 2021
    

19. N6-methyladenosine reader protein IGF2BP1 suppresses CD8 + T cells-mediated tumor cytotoxicity and apoptosis in colon cancer

    Tumor immune escape is an important manner for colon cancer to escape effective killing by immune system. Currently, the immune checkpoint...

    Yao Peng, Zhili Zhang, ... Long Xu in Apoptosis

    Article 17 October 2023
    

20. Transcriptome-wide map of N6-methyladenosine (m6A) profiling in coronary artery disease (CAD) with clopidogrel resistance

    Background

    Clopidogrel resistance profoundly increases the risk of major cardiovascular events in coronary artery disease (CAD) patients. Here, we...

    Ruoyan Yu, Qinglin Yu, ... Jia Su in Clinical Epigenetics

    Article Open access 15 December 2023