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A Review of Molecular Interplay between Neurotrophins and miRNAs in Neuropsychological Disorders
Various neurotrophins (NTs), including nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4, promote cellular...
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CVD phenoty** in oncologic disorders: cardio-miRNAs as a potential target to improve individual outcomes in revers cardio-oncology
With the increase of aging population and prevalence of obesity, the incidence of cardiovascular disease (CVD) and cancer has also presented an...
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Circulating MiRNAs Are Associated With Low-grade Systemic Inflammation and Leptin Levels in Older Adults
Inflammaging refers to the low-grade systemic inflammation that occurs with aging present in chronic non-communicable diseases. MicroRNAs (miRNAs)...
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Cannabinoids in Cancer: Cross-talk Between Cannabinoids and miRNAs
At present, the pharmacological applications of exogenous cannabinoids have been validated, and an increasing number of studies have shown their role...
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The role of Exosomal miRNAs in cancer
Exosomal miRNAs have attracted much attention due to their critical role in regulating genes and the altered expression of miRNAs in virtually all...
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Functions and targets of miRNAs in pharmacological and toxicological effects of major components of Tripterygium wilfordii Hook F
Tripterygium wilfordii Hook F (TwHF) has a long history of use as a traditional Chinese medicine and has been widely administered to treat various...
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An In Vitro Study for the Role of Schizophrenia-Related Potential miRNAs in the Regulation of COMT Gene
This study aimed to analyze the possible association of miR-30a-5p, miR-30e-5p, and miR-34a-5p identified as potential candidate miRNAs in...
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Evaluation of serum miRNAs expression in frail and robust subjects undergoing multicomponent exercise protocol (VIVIFRAIL)
BackgroundFrailty, defined as physical performance impairment, is a common condition in older adults and can anticipate the development of...
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Stem Cell-Derived Exosomal MicroRNAs as Novel Potential Approach for Multiple Sclerosis Treatment
Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterized by inflammation and demyelination of CNS neurons....
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Detection of Deregulated miRNAs in Childhood Epileptic Encephalopathies
The term “epileptic encephalopathy” is used to describe a possible relationship between epilepsy and developmental delay. The pathogenesis of...
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miRNAs as potential diagnostic biomarkers and pharmacogenomic indicators in psychiatric disorders
The heterogeneity of psychiatric disorders and the lack of reliable biomarkers for prediction and treatments follow-up pose difficulties towards...
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Mechanistic Evaluation of miRNAs and Their Targeted Genes in the Pathogenesis and Therapeutics of Parkinson’s Disease
MicroRNA (miRNA) are usually 18–25 nucleotides long non-coding RNA targeting post-transcriptional regulation of genes involved in various biological...
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Dysregulated miRNAs in Progression and Pathogenesis of Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive degeneration of neurons due to the accumulation of amyloid-β peptide (Aβ) and hyper-phosphorylation of tau...
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miRNAs as the important regulators of myasthenia gravis: involvement of major cytokines and immune cells
Myasthenia gravis (MG) is a type of muscle paralysis created by immune responses against acetylcholine receptor proteins in neuromuscular synapses....
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MALAT1-miRNAs network regulate thymidylate synthase and affect 5FU-based chemotherapy
BackgroundThe active metabolite of 5-Fluorouracil (5FU), used in the treatment of several types of cancer, acts by inhibiting the thymidylate...
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Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease
Discoidin Domain Receptor (DDR)-1 is activated by collagen. Nilotinib is a tyrosine kinase inhibitor that is FDA-approved for leukemia and potently...
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Design and Fabrication of a DNA-copper Nanocluster-based Biosensor for Multiple Detections of Circulating miRNAs in Early Screening of Breast Cancer
Breast cancer is one of the most prevalent cancers and a significant cause of fatalities in women. Diagnosis of breast cancer faces substantial...
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Plasma Exo-miRNAs Correlated with AD-Related Factors of Chinese Individuals Involved in Aβ Accumulation and Cognition Decline
Numerous studies have investigated the risk factors of Alzheimer’s disease (AD); however, AD-risk factors related miRNAs were rarely reported. In...
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Exosome Content–Mediated Signaling Pathways in Multiple Sclerosis
Exosomes are small extracellular vesicles with a complex lipid-bilayer surface and 30–150 nm diameter. These vesicles play a critical role in...
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Genome-wide identification of chicken bursae of Fabricius miRNAs in response to very virulent infectious bursal disease virus
Infectious bursal disease virus (IBDV) can cause a highly contagious immunosuppressive disease in young chickens. MicroRNAs (miRNAs) are crucial...
