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Piezo1 channel activation facilitates baroreflex afferent neurotransmission with subsequent blood pressure reduction in control and hypertension rats
Mechanosensitive cation channels such as Piezo1 and Piezo2 are activated by mechanical force like a starched wall of the aorta while blood pressure...
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Sodium oligomannate activates the enteroendocrine-vagal afferent pathways in APP/PS1 mice
Enteroendocrine cells (EECs) and vagal afferent neurons constitute functional sensory units of the gut, which have been implicated in bottom-up...
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Neurogenetics of Memory, Learning, and Forgetting
Animals are able to learn from past experiences and change their behavior. To understand the mechanisms underlying these learning and memory... -
Evidence for the cholinergic markers ChAT and vAChT in sensory cells of the develo** antennal nervous system of the desert locust Schistocerca gregaria
Sensory and motor systems in insects with hemimetabolous development must be ready to mediate adaptive behavior directly on hatching from the egg....
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Epithelial-Neuronal Communication in Visceral Pain
Visceral hypersensitivity and pain are common symptoms of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Pain results, at least... -
Retinal nerve fibre layer thinning and corneal nerve loss in patients with Bardet-Biedl syndrome
BackgroundBardet-Biedl syndrome (BBS) is an autosomal recessive, genetically heterogeneous, pleiotropic disorder caused by variants in genes involved...
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Insect Hearing: Selected Historical Vignettes
How insects hear has understandably been influenced by what we know about how vertebrates hear. However, insects are among the smallest of... -
Dispensable role of Rac1 and Rac3 after cochlear hair cell specification
AbstractRac small GTPases play important roles during embryonic development of the inner ear; however, little is known regarding their function in...
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Three-dimensional architecture of a mechanoreceptor in the brown planthopper, Nilaparvata lugens, revealed by FIB-SEM
Trichoid sensilla are the most common mechanoreceptors in insects; depending on their distribution, they can act as either exteroceptors or...
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Somatosensation
The somatosensory system enables organisms to feel, to ache, to chill, and, perhaps most importantly, to know which parts of the body are involved in... -
Insect Dorsal Ocelli: A Brief Overview
The dorsal ocelli of adult insects are simple eyes that can complement or act independently from the compound eye visual system. While notably absent... -
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Biomechanical control of lymphatic vessel physiology and functions
The ever-growing research on lymphatic biology has clearly identified lymphatic vessels as key players that maintain human health through their...
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Doublecortin-like kinase is required for cnidocyte development in Nematostella vectensis
The complex morphology of neurons requires precise control of their microtubule cytoskeleton. This is achieved by microtubule-associated proteins...
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Patch-seq: Advances and Biological Applications
Multimodal analysis of gene-expression patterns, electrophysiological properties, and morphological phenotypes at the single-cell/single-nucleus...
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SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation
Reissner’s fiber (RF) is an extracellular polymer comprising the large monomeric protein SCO-spondin (SSPO) secreted by the subcommissural organ...