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Increasing clinician participation in tobacco cessation by an implementation science-based tobacco cessation champion program
BackgroundWe designed a process to increase tobacco cessation in an academic center and its widely distributed network community sites using clinical...
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Implementation of the WHO core components of an infection prevention and control programme in two sub-saharan African acute health-care facilities: a mixed methods study
BackgroundThe coronavirus pandemic again highlighted the need for robust health care facility infection prevention and control (IPC) programmes. WHO...
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Combinatorial strategies to target RAS-driven cancers
Although RAS was formerly considered undruggable, various agents that inhibit RAS or specific RAS oncoproteins have now been developed. Indeed, the...
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Emerging vaccine strategies against the incessant pneumococcal disease
The incidence of invasive pneumococcal disease (IPD) caused by infection with the pathogen Streptococcus pneumoniae ( Spn ) has been on a downward...
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Implementation During a Pandemic: Findings, Successes, and Lessons Learned from Community Grantees
Funding communities through mini-grant programs builds community capacity by fostering leadership among community members, develo** expertise in...
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Clinical implementation of magnetic resonance imaging simulation for radiation oncology planning: 5 year experience
PurposeIntegrating magnetic resonance (MR) into radiotherapy planning has several advantages. This report details the clinical implementation of an...
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Optimizing process flow diagrams to guide implementation of a colorectal cancer screening intervention in new settings
PurposeThe goal of this study was to assess acceptability of using process flow diagrams (or process maps) depicting a previously implemented...
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Exploring knowledge and implementation gaps of activity-based therapy in centers lacking specialized spinal cord injury services: understanding therapists’ perspectives
Study designQualitative exploratory
ObjectivesRehabilitation following spinal cord injury (SCI) is a life-long process involving healthcare in a...
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Evaluation of a multifaceted implementation strategy for semi-automated surveillance of surgical site infections after total hip or knee arthroplasty: a multicentre pilot study in the Netherlands
IntroductionTo promote the nation-wide implementation of semi-automated surveillance (AS) of surgical site infection after hip and knee arthroplasty,...
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Investigating genomic medicine practice and perceptions amongst Australian non-genetics physicians to inform education and implementation
Genomic medicine is being implemented on a global scale, requiring a genomic-competent health workforce. To inform education as part of...
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Knowledge and attitude of healthcare prescribers and pharmacists toward antimicrobial stewardship program and the barriers for its implementation
BackgroundAntimicrobial stewardship (ASP) is considered a key prevention strategy in addressing the worldwide concern of accelerating antimicrobial...
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HPV self-sampling among women in the United States: preferences for implementation
PurposeWith the inclusion of primary HPV testing in 2018 U.S. Preventive Services Taskforce guidelines, at-home HPV self-sampling may provide a...
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Revolutionizing Lung Cancer Treatment: Innovative CRISPR-Cas9 Delivery Strategies
Lung carcinoma, including both non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), remains a significant global health challenge...
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The implementation of large-scale genomic screening or diagnostic programmes: A rapid evidence review
Genomic healthcare programmes, both in a research and clinical context, have demonstrated a pivotal opportunity to prevent, diagnose, and treat rare...
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Enrichment strategies to enhance genome editing
Genome editing technologies hold great promise for numerous applications including the understanding of cellular and disease mechanisms and the...
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Multimodal environmental cleaning strategies to prevent healthcare-associated infections
Infection transmission in healthcare is multifaceted and by in large involves the complex interplay between a pathogen, a host and their environment....
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Vaccination and screening strategies to accelerate cervical cancer elimination in Norway: a model-based analysis
BackgroundExperts have proposed an ‘EVEN FASTER’ concept targeting age-groups maintaining circulation of human papillomavirus (HPV). We explored...
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Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
Polygenic risk scores (PRSs) have improved in predictive performance, but several challenges remain to be addressed before PRSs can be implemented in...
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Public hospital pharmacists’ knowledge, attitudes, and practices for antibiotic stewardship implementation in Limpopo Province, South Africa
BackgroundHospital pharmacists are important in antibiotic stewardship programs (ASP), a global strategy to combat antibiotic resistance (ABR). South...
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Map** malaria vectors and insecticide resistance in a high-endemic district of Haryana, India: implications for vector control strategies
BackgroundAchieving effective control and elimination of malaria in endemic regions necessitates a comprehensive understanding of local mosquito...
