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Immunogenic Cell Death-related Signature Evaluates the Tumor Microenvironment and Predicts the Prognosis in Diffuse Large B-Cell Lymphoma
Current literatures suggest a growing body of evidence highlighting the pivotal role of Immunogenic Cell Death (ICD) in multiple tumor types....
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Analyzing molecular ty** and clinical application of immunogenic cell death-related genes in hepatocellular carcinoma
BackgroundHepatocellular carcinoma (HCC) is considered one of the most common cancers, characterized by low early detection and high mortality rates,...
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An immunogenic cell death-related signature predicts prognosis and immunotherapy response in stomach adenocarcinoma
The immunogenic cell death (ICD) is a specific type of regulatory cell death (RCD), which induces adaptive immunity against antigens of dead cells....
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Discovery of highly immunogenic spleen-resident FCGR3+CD103+ cDC1s differentiated by IL-33-primed ST2+ basophils
Recombinant interleukin-33 (IL-33) inhibits tumor growth, but the detailed immunological mechanism is still unknown. IL-33-mediated tumor suppression...
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Chronic LCMV infection regulates the effector T cell response by inducing the generation of less immunogenic dendritic cells
Chronic viral infection impairs systemic immunity in the host; however, the mechanism underlying the dysfunction of immune cells in chronic viral...
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Urinary Gluten Immunogenic Peptides as a Biomarker in Celiac Patients
Celiac disease (CD) is treated with a lifelong gluten-free diet (GFD). Current methods for monitoring GFD conformance, such as dietary...
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A novel immunogenic cell death-related classification indicates the immune landscape and predicts clinical outcome and treatment response in acute myeloid leukemia
BackgroundImmunogenic cell death (ICD) is closely related to anti-tumor therapy and regulates the tumor microenvironment (TME). This study aims to...
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Multi-omics identification of an immunogenic cell death-related signature for clear cell renal cell carcinoma in the context of 3P medicine and based on a 101-combination machine learning computational framework
BackgroundClear cell renal cell carcinoma (ccRCC) is a prevalent urological malignancy associated with a high mortality rate. The lack of a reliable...
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Urinary Gluten Immunogenic Peptides as a Biomarker in Celiac Patients
Celiac disease (CD) is treated with a lifelong gluten-free diet (GFD). Current methods for monitoring GFD conformance, such as dietary...
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Targeting of focal adhesion kinase enhances the immunogenic cell death of PEGylated liposome doxorubicin to optimize therapeutic responses of immune checkpoint blockade
BackgroundsImmune checkpoint blockade (ICB) is widely considered to exert long-term treatment benefits by activating antitumor immunity. However,...
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Isoquercitrin Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Gastric Cancer Cells
Isoquercitrin is a natural flavonoid quercetin with anti-inflammatory, anti-anaphylactic, antiviral, and anticancer activities. Here, we investigated...
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Immunogenic cell death and its therapeutic or prognostic potential in high-grade glioma
Immunogenic cell death (ICD) has emerged as a key component of therapy-induced anti-tumor immunity. Over the past few years, ICD was found to play a...
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Comprehensive analysis of the immunogenic cell death-related signature for predicting prognosis and immunotherapy efficiency in patients with lung adenocarcinoma
BackgroundAlthough immunotherapy has been considered as a potent strategy for lung adenocarcinoma (LUAD), only a small part of patients was served as...
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Inhibition of phospholipase D1 induces immunogenic cell death and potentiates cancer immunotherapy in colorectal cancer
Phospholipase D (PLD) is a potential therapeutic target against cancer. However, the contribution of PLD inhibition to the antitumor response remains...
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Classification and clinical significance of immunogenic cell death-related genes in Plasmodium falciparum infection determined by integrated bioinformatics analysis and machine learning
BackgroundImmunogenic cell death (ICD) is a type of regulated cell death that plays a crucial role in activating the immune system in response to...
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Highly stable and immunogenic CMV T cell vaccine candidate developed using a synthetic MVA platform
Human cytomegalovirus (CMV) is the most common infectious cause of complications post-transplantation, while a CMV vaccine for transplant recipients...
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Screening of immunogenic proteins and evaluation of vaccine candidates against Mycoplasma synoviae
Mycoplasma synoviae ( M. synoviae ) is a serious avian pathogen that causes significant economic losses to chicken and turkey producers worldwide. The...
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Targeting purinergic pathway to enhance radiotherapy-induced immunogenic cancer cell death
Emerging evidence has demonstrated that radiotherapy (RT) can not only cause direct damage to cancer cells but also lead to immunogenic cell death...
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Definition of a Novel Immunogenic Cell Death-Relevant Gene Signature Associated with Immune Landscape in Gastric Cancer
Immunogenic cell death (ICD) induces anti-tumor immunity and aids in dismantling the immunosuppressive immune microenvironment (TME), which belongs...
