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Systemic Onco-Sphere: Host Metabolic System and Cancer
It is well established that patients with altered metabolism manifesting as obesity, metabolic syndrome and chronic inflammation have an increased...
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The Impact of Sex and Gender in Medicine and Pharmacology
Sex and gender play a pivotal role in health and disease. Differences can be identified in symptoms, biomarkers, lifetime experiences of diseases,...
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The conne**on between sex and immune responses
There are notable sex-based differences in immune responses to pathogens and self-antigens, with female individuals exhibiting increased...
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Gut microbiome-metabolome interactions predict host condition
BackgroundThe effect of microbes on their human host is often mediated through changes in metabolite concentrations. As such, multiple tools have...
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Factors That Determine Microsporidia Infection and Host Specificity
Microsporidia are a large phylum of obligate intracellular parasites that infect an extremely diverse range of animals and protists. In this chapter,...
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Contribution of parasite and host genotype to immunopathology of schistosome infections
BackgroundThe role of pathogen genotype in determining disease severity and immunopathology has been studied intensively in microbial pathogens...
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Plasmodium: Vertebrate Host
Plasmodium spp. infection remains as a major global health problem, being annually responsible for a large number of deaths. Disease eradication...
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Bacterial SNPs in the human gut microbiome associate with host BMI
Genome-wide association studies (GWASs) have provided numerous associations between human single-nucleotide polymorphisms (SNPs) and health traits....
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Expression of sex-specific molecular markers by Babesia bovis gametes
BackgroundBovine babesiosis caused by Babesia bovis is one of the most important tick-borne diseases of cattle in tropical and subtropical regions. Ba...
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The Influence of Sex Hormones and X Chromosome in Immune Responses
Males and females differ in their susceptibility to develop autoimmunity and allergy but also in their capacity to cope with infections and cancers....
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New host and locality records of helminths’ infection of seven lizards from Morocco
Morocco has a great diversity of reptiles; more than 26% of the herpetofauna species are considered to be endemic. Nevertheless, there is little...
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Transcriptional patterns of sexual dimorphism and in host developmental programs in the model parasitic nematode Heligmosomoides bakeri
BackgroundHeligmosomoides bakeri (often mistaken for Heligmosomoides polygyrus ) is a promising model for parasitic nematodes with the key advantage...
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Biological Sex and Pregnancy Affect Influenza Pathogenesis and Vaccination
Males and females differ in the outcome of influenza A virus (IAV) infections, which depends significantly on age. During seasonal influenza...
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Microbial composition, functionality, and stress resilience or susceptibility: unraveling sex-specific patterns
BackgroundFollowing exposure to traumatic stress, women are twice as likely as men to develop mood disorders. Yet, individual responses to such...
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Intraspecific variation of body size in fleas: effects of host sex and flea phenology
We investigated the effects of host sex and flea phenology (estimated as periods of high versus low abundance) on individual body size in four fleas...
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Association of TLR8 Variants in Sex-Based Clinical Differences in Patients with COVID-19
The host immune response might confer differential vulnerability to SARS‐CoV‐2 infection. The Toll-like receptor 8 ( TLR8 ), could participated for...
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No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host
BackgroundThe trematode parasite Schistosoma mansoni uses an aquatic snail intermediate and a vertebrate definitive host to complete its life cycle....
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Sex at the interface: the origin and impact of sex differences in the develo** human placenta
The fetal placenta is a source of hormones and immune factors that play a vital role in maintaining pregnancy and facilitating fetal growth. Cells in...
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Genetic hypogonadal mouse model reveals niche-specific influence of reproductive axis and sex on intestinal microbial communities
BackgroundThe gut microbiome has been linked to many diseases with sex bias including autoimmune, metabolic, neurological, and reproductive...
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Mixed-sex clusters on grass blades: breeding strategy of the ornate dog tick, Dermacentor reticulatus
BackgroundThe ornate dog tick Dermacentor reticulatus is second only to the hard tick Ixodes ricinus in terms of importance as a vector of...
