Search
Search Results
-
Falsified and problematic methandienone products available online: active pharmaceutical ingredient identification by portable Raman spectrometers and quantification by ultra-high-performance liquid chromatography–Fourier transform mass spectrometry
This study aimed on the one hand to clarify the quality, authenticity, safety, and other issues related to products of the anabolic-androgenic...
-
Immunoprecipitation Followed by Mass Spectrometry: An Approach for Identifying Host–Viral Protein–Protein Interactions
As obligate intracellular parasites, viruses rely on the efficient manipulation of the cell they invade in order to multiply and spread....
-
Use of Affinity Purification–Mass Spectrometry to Identify Phosphorylated Tau Interactors in Alzheimer’s Disease
Phosphorylated tau is the main protein present in neurofibrillary tangles, the presence of which is a key neuropathological hallmark of Alzheimer’s...
-
Isolation and Mass Spectrometry-Based Profiling of Major Lipids in Brown Adipose Tissue
Brown adipose tissue (BAT) is an important regulator of metabolic homeostasis through its role in adaptive thermogenesis and control of whole-body...
-
Developments in high-resolution mass spectrometric analyses of new psychoactive substances
The proliferation of new psychoactive substances (NPS) has necessitated the development and improvement of current practices for the detection and...
-
Standardization of a Mass Spectrometry-Based Workflow for Food Allergen Quantification
In this chapter, the analytical workflow typically used for the development and validation of an analytical method tailored to food allergen...
-
Oxonium ion scanning mass spectrometry for large-scale plasma glycoproteomics
Protein glycosylation, a complex and heterogeneous post-translational modification that is frequently dysregulated in disease, has been difficult to...
-
Biomarker Identification in Liver Cancers Using Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) Imaging: An Approach for Spatially Resolved Metabolomics
Liver cancers are characterized by interindividual and intratumoral heterogeneity, which makes early diagnosis and the development of therapies...
-
Mass spectrometry imaging: new eyes on natural products for drug research and development
Natural products (NPs) and their structural analogs represent a major source of novel drug development for disease prevention and treatment. The...
-
Mass spectrometry imaging in gynecological cancers: the best is yet to come
Mass spectrometry imaging (MSI) enables obtaining multidimensional results simultaneously in a single run, including regiospecificity and m/z values...
-
The emerging role of mass spectrometry-based proteomics in drug discovery
Proteins are the main targets of most drugs; however, system-wide methods to monitor protein activity and function are still underused in drug...
-
Breaking the Mucin Barrier: A New Affinity Chromatography-Mass Spectrometry Approach to Unveil Potential Cell Markers and Pathways Altered in Pseudomyxoma Peritonei
BackgroundPseudomyxoma peritonei (PMP) is a rare peritoneal mucinous carcinomatosis with largely unknown underlying molecular mechanisms....
-
Assessment of an exhaled breath test using ultraviolet photoionization time-of-flight mass spectrometry for the monitoring of kidney transplant recipients
Continuous monitoring for immunosuppressive status, infection and complications are a must for kidney transplantation (KTx) recipients. Traditional...
-
Analysis of Carbohydrates by Mass Spectrometry
Mass spectrometry has become the favorite technique for glycomics analysis. This chapter describes the different ionization methods and provides...
-
Transcriptome Sequencing and Mass Spectrometry Reveal Genes Involved in the Non-mendelian Inheritance-Mediated Feather Growth Rate in Chicken
The feather growth rate in chickens included early and late feathering. We attempted to characterize the genes and pathways associated with the...
-
Comprehensive Two-Dimensional Gas Chromatography Mass Spectrometry-Based Metabolomics
Compared to one-dimensional gas chromatography with mass spectrometry (GC-MS), GC × GC-MS provides significantly increased peak capacity, resolution,...
-
Omic-Based Biomarkers Discovery in Alzheimer’s Disease: High-Throughput Approaches
The discovery of novel metabolomic, proteomic, lipidomic, and transcriptomic (mRNA and miRNA) biomarkers in serum, plasma, brain, and CSF is a...
-
Omic-Based Biomarkers Discovery in Alzheimer’s Disease: High-Throughput Approaches
The discovery of novel metabolomic, proteomic, lipidomic, and transcriptomic (mRNA and miRNA) biomarkers in serum, plasma, brain, and CSF is a...
-
Advances in single-cell omics and multiomics for high-resolution molecular profiling
Single-cell omics technologies have revolutionized molecular profiling by providing high-resolution insights into cellular heterogeneity and...
-
Compound Identification Strategies in Mass Spectrometry-Based Metabolomics and Pharmacometabolomics
The metabolome is composed of a vast array of molecules, including endogenous metabolites and lipids, diet- and microbiome-derived substances,...