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Surveillance and epidemiological characterization of human adenovirus infections among outpatient children with acute gastroenteritis during the COVID-19 epidemic in Shanghai, China
BackgroundHuman adenovirus (HAdV) has been recognized as one of the common enteric viruses associated with acute gastroenteritis (AGE) in children....
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Recombinant fiber-1 protein of fowl adenovirus serotype 4 induces high levels of neutralizing antibodies in immunized chickens
Virulent fowl adenovirus serotype 4 (FAdV-4) causes hydropericardium syndrome (HPS) with high mortality in chickens, leading to significant economic...
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Assessing the Response of Human NK Cell Subsets to Infection by Clinically Isolated Virus Strains
Natural killer (NK) cells play a critical role in defending against virus infections. Investigating human NK cell antiviral functions is of prime...
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The Emergence and Widespread Circulation of Enteric Viruses Throughout the COVID-19 Pandemic: A Wastewater-Based Evidence
Growing evidence shed light on the importance of wastewater-based epidemiology (WBE) during the pandemic, when the patients rarely visited the...
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Adenoviruses
Adenoviruses belong to the family Adenoviridae, consisting of a group of medium-sized, non-enveloped, double-stranded DNA (dsDNA) viruses that share...
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A fatal case of viral sepsis and encephalitis in a child caused by human adenovirus type 7 infection
Adenoviruses are highly prevalent pathogens responsible for a wide range of clinical diseases, including respiratory tract infection, acute...
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Potent antitumor efficacy of human dental pulp stem cells armed with YSCH-01 oncolytic adenovirus
BackgroundSystemic administration of oncolytic adenovirus for cancer therapy is still a challenge. Mesenchymal stem cells as cell carriers have...
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Intravesical instillation-based mTOR-STAT3 dual targeting for bladder cancer treatment
BackgroundRecent intravesical administration of adenoviral vectors, either as a single injection or in combination with immune checkpoint inhibitors,...
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Direct evidence of fiber-protein-directed hemagglutination by canine adenoviruses
Canine adenoviruses (CAdVs) are divided into two serotypes, CAdV1 and CAdV2, whose members mainly cause infectious hepatitis and laryngotracheitis,...
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Molecular characterization of a bovine adenovirus type 7 (Bovine Atadenovirus F) strain isolated from a systemically infected calf in Germany
Bovine adenovirus 7 (BAdV-7) is an unclassified member of the genus Atadenovirus with a worldwide distribution and has been reported to induce...
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Complete genome sequence of a novel bat mastadenovirus C strain isolated from Rhinolophus cornutus in Japan
Here, we report a novel bat adenovirus strain isolated from apparently healthy bats of the species Rhinolophus cornutus in Japan. The genome of the...
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Immunoinformatic Risk Assessment of Host Cell Proteins During Process Development for Biologic Therapeutics
The identification and removal of host cell proteins (HCPs) from biologic products is a critical step in drug development. Despite recent...
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Oncolytic adenovirus encoding apolipoprotein A1 suppresses metastasis of triple-negative breast cancer in mice
BackgroundDysregulation of cholesterol metabolism is associated with the metastasis of triple-negative breast cancer (TNBC). Apolipoprotein A1...
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First evidence of a new simian adenovirus clustering with Human mastadenovirus F viruses
BackgroundAdenoviruses play an important role as human pathogens, though most infections are believed to be asymptomatic. The over 100 human...
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Genomic characterization of psittacine adenovirus 2, a siadenovirus identified in a moribund African grey parrot (Psittacus erithacus)
Here, we report the complete genome sequence of psittacine adenovirus 2 from a moribund African grey parrot ( Psittacus erithacus ) with neurological...
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An insertion and deletion mutant of adenovirus in Muscovy ducks
Duck adenovirus 3 (DuAdV-3; strain HB) was isolated and sequenced. The genome of the Muscovy-duck-origin virus contains a 54-bp insertion in pVIII, a...
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Molecular evolution of human adenovirus type 16 through multiple recombination events
Human mastadenoviruses (HAdVs) are non-enveloped, double-stranded DNA viruses that are comprised of more than 85 types classified within seven...
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An intranasal combination vaccine induces systemic and mucosal immunity against COVID-19 and influenza
Despite prolonged surveillance and interventions, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses continue to...
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Molecular and epidemiological characterization of human adenoviruses infection among children with acute diarrhea in Shandong Province, China
BackgroundHuman adenovirus (HAdV) had been recognized as one of the most common enteric viruses associated with acute diarrhea in children. The...
