Search
Search Results
-
Diet-induced inflammation in the anterior paraventricular thalamus induces compulsive sucrose-seeking
Overconsumption of palatable food may initiate neuroadaptive responses in brain reward circuitry that may contribute to eating disorders. Here we...
-
Investigating individual differences in opioid-taking and opioid-seeking behavior in male rats
RationaleUnderstanding the behavioral and neurobiological factors that render some individuals more susceptible than others to opioid addiction will...
-
Cocaine-induced plasticity, motivation, and cue responsivity do not differ in obesity-prone vs obesity-resistant rats; implications for food addiction
RationaleCompared to obesity-resistant rats, obesity-prone rats consume more food, work harder to obtain food, show greater motivational responses to...
-
Ceftriaxone reverses diet-induced deficits in goal-directed control
RationaleObesity is associated with numerous health risks and ever-increasing rates are a significant global concern. However, despite weight loss...
-
Liraglutide attenuates nicotine self-administration as well as nicotine seeking and hyperphagia during withdrawal in male and female rats
RationaleNicotine cessation is associated with increased consumption of highly palatable foods and body weight gain in most smokers. Concerns about...
-
Effects of fentanyl self-administration on risk-taking behavior in male rats
RationaleIndividuals with opioid use disorder (OUD) exhibit impaired decision making and elevated risk-taking behavior. In contrast to the effects of...
-
Early resource scarcity alters motivation for natural rewards in a sex- and reinforcer-dependent manner
RationaleEarly life adversity impacts reward-related behaviors, including reward seeking for drugs of abuse. However, the effects of early stress on...
-
NLRP3 deficiency decreases alcohol intake controlling anxiety-like behavior via modification of glutamatergic transmission in corticostriatal circuits
BackgroundAlcohol use disorders result from repeated binge and chronic alcohol consumption followed by negative effects, such as anxiety, upon...
-
Dopamine, behavior, and addiction
Addictive drugs are habit-forming. Addiction is a learned behavior; repeated exposure to addictive drugs can stamp in learning. Dopamine-depleted or...
-
Novelty-induced locomotor behavior predicts heroin addiction vulnerability in male, but not female, rats
RationaleThe ongoing rise in opioid use disorder (OUD) has made it imperative to better model the individual variation within the human population...
-
Transgenerational Susceptibility to Food Addiction-Like Behavior in Rats Associates to a Decrease of the Anti-Inflammatory IL-10 in Plasma
Maternal nutritional programming by energy-dense foods leads to the transgenerational heritance of addiction-like behavior. Exposure to energy-dense...
-
Liposaccharide-induced sustained mild inflammation fragments social behavior and alters basolateral amygdala activity
RationaleConditions with sustained low-grade inflammation have high comorbidity with depression and anxiety and are associated with social...
-
Medial orbitofrontal cortical regulation of different aspects of Pavlovian and instrumental reward seeking
RationaleThe medial subregion of the orbitofrontal cortex (mOFC) is thought to play an important role representing the expected outcome of a given...
-
Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus
The prefrontal cortex (PFC) enables mammals to respond to situations, including internal states, with appropriate actions. One such internal state...
-
Parental Behavior in Carnivores
The mammalian order Carnivora is generally defined as species that feed exclusively or to some degree by eating other animals. The Carnivora comprise...
-
Parental Behavior in Bovines
After approximately 9 months, cows give birth to one calf. They usually try to separate from the herd if kept outdoors, but this depends on the...
-
Prenatal Hypoxia Impairs Olfactory Function in Postnatal Ontogeny in Rats
Analysis of the age-related dynamics of olfactory behavior in the odor preference and food search testsshowed that all male Wistar rats, regardless...
-
A Deep Mesencephalic Nucleus Circuit Regulates Licking Behavior
Licking behavior is important for water intake. The deep mesencephalic nucleus (DpMe) has been implicated in instinctive behaviors. However, whether...
-
Indoor resting behavior of Aedes aegypti (Diptera: Culicidae) in northeastern Thailand
BackgroundAedes aegypti is a vector of several arboviruses, notably dengue virus (DENV), which causes dengue fever and is often found resting...
-
Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice
BackgroundAlzheimer's disease is accompanied by an abnormal high accumulation of cis-P tau. However, the long-term changes in behavior following tau...
