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Human adaptation to high altitude: a review of convergence between genomic and proteomic signatures
Both genomics- and proteomics-based investigations have identified several essential genes, proteins, and pathways that may facilitate human adaptive...
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Genetic and epigenetic polymorphisms of eNOS and CYP2D6 in mainland Chinese Tibetan, Mongolian, Uygur, and Han populations
Cytochrome P450 2D6 (CYP2D6) and endothelial nitric oxide synthase (eNOS) are important in the cardiovascular disease susceptibility and drug...
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Echinococcus multilocularis and Echinococcus shiquicus in a small mammal community on the eastern Tibetan Plateau: host species composition, molecular prevalence, and epidemiological implications
BackgroundThe eastern part of the Tibetan Plateau is now recognized as an endemic region with the highest reported human infection rates in the world...
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First detection and genetic characterization of ungulate tetraparvovirus 2 and ungulate tetraparvovirus 4 in special livestock on the Qinghai-Tibet Plateau in China
Tetraparvovirus , formerly known as Partetravirus , is a newly discovered genus in the family Parvoviridae that is considered phylogenetically distinct...
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On the Genetic Structure of Harmonia axyridis (Coleoptera, Coccinellidae) Populations in Native and Invasive Ranges, View from a Position of Molecular Genetics
AbstractHarmonia axyridis Pallas (1773) (Coleoptera: Coccinellidae) is one of the most studied invasive species of insects. H . axyridis appeared in...
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The impact of environmental factors on human echinococcosis epidemics: spatial modelling and risk prediction
BackgroundHuman echinococcosis is affected by natural environmental factors, and its prevalence shows a distinct geographical distribution. Western...
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Light and Electron Microscopical Aspects of Stages of Echinococcus Species Around the World
The relationships between the different species of the Echinococcus group are still under intense discussion today. Many of them occur worldwide in...
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Cross-continental admixture in the Kho population from northwest Pakistan
Northern Pakistan is home to many diverse ethnicities and languages. The region acted as a prime corridor for ancient invasions and population...
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Genome-wide allele and haplotype-sharing patterns suggested one unique Hmong–Mein-related lineage and biological adaptation history in Southwest China
BackgroundFine-scale genetic structure of ethnolinguistically diverse Chinese populations can fill the gap in the missing diversity and evolutionary...
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Emergence of lumpy skin disease virus (LSDV) infection in domestic Himalayan yaks (Bos grunniens) in Himachal Pradesh, India
In this study, we investigated and confirmed natural lumpy skin disease virus (LSDV) infection in Himalayan yaks ( Bos grunniens ) in Himachal Pradesh,...
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Molecular Detection of Indigenous Hepatitis E Virus (HEV) from Tibetan Pigs in Tibet, China
Hepatitis E is an important public health concern throughout the world. Many molecular and serological surveys have reported the prevalence and...
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More than a decade of genetic research on the Denisovans
Denisovans, a group of now extinct humans who lived in Eastern Eurasia in the Middle and Late Pleistocene, were first identified from DNA sequences...
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Mitochondrial genome data confirm that yaks can serve as the intermediate host of Echinococcus canadensis (G10) on the Tibetan Plateau
BackgroundCervids used to be considered the only animal intermediate hosts of the G10 genotype of Echinococcus canadensis. Yaks are often herded in...
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First description of Echinococcus ortleppi infection in China
BackgroundEchinococcosis has led to considerable social and economic losses in China, particularly in the endemic communities of the eastern Tibetan...
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Effect of sunitinib against Echinococcus multilocularis through inhibition of VEGFA-induced angiogenesis
BackgroundAlveolar echinococcosis (AE) is a lethal zoonosis caused by the fox tapeworm Echinococcus multilocularis. The disease is difficult to...
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Molecular detection and prevalence of Cryptosporidium spp. infections in two types of domestic farm animals in the Qinghai-Tibetan Plateau Area (QTPA) in China
The objective of this study was to determine the prevalence of Cryptosporidium species infections in young cattle and sheep in the north-eastern part...
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Cystic and Alveolar Echinococcosis: Fraternal Twins Both in Search of Optimal Treatment
The burden of the two different diseases, “cystic echinococcosis” (CE), due to several species of Echinococcus among the E. granulosus sensu lato...
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Cystic and Alveolar Echinococcosis: Fraternal Twins Both in Search of Optimal Treatment
The burden of the two different diseases, “cystic echinococcosis” (CE), due to several species of Echinococcus among the E. granulosus sensu lato...
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Characteristics of Microbial Community and Enzyme Activities in Higher Altitude Regions
The high altitude regions around the world consist of an interesting group of landscapes with diverse features and microbial diversity. These regions...
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Genomic Diversity of 75 Communities in India
Alu Kurumba has an ancestor cult, which is their mythic ancestors called Kurupade—Tayi (Mother of the multiple or Army of the Alu Kurumbas)....