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Epidemiology of dengue in SAARC territory: a systematic review and meta-analysis
BackgroundDengue is one of the common arboviral infections and is a public health problem in South East Asia. The aim of this systematic review and...
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Is new dengue vaccine efficacy data a relief or cause for concern?
Dengue is a major global public health problem requiring a safe and efficacious vaccine as the foundation of a comprehensive countermeasure strategy....
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Co-infection of dengue and Zika viruses mutually enhances viral replication in the mosquito Aedes aegypti
BackgroundThe mosquito Aedes aegypti transmits two of the most serious mosquito-borne viruses, dengue virus (DENV) and Zika virus (ZIKV), which...
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Genetic characterization of dengue virus from patients presenting multi-serotypic infections in the Northern West Bengal, India
Northern West Bengal, popularly known as North Bengal, is a dengue-endemic area, which has been severely affected by Dengue in the past few years...
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Attenuated Dengue virus PV001-DV induces oncolytic tumor cell death and potent immune responses
BackgroundViral therapies developed for cancer treatment have classically prioritized direct oncolytic effects over their immune activating...
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Integrated systems immunology approach identifies impaired effector T cell memory responses as a feature of progression to severe dengue fever
BackgroundTypical symptoms of uncomplicated dengue fever (DF) include headache, muscle pains, rash, cough, and vomiting. A proportion of cases...
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Global and cell type-specific immunological hallmarks of severe dengue progression identified via a systems immunology approach
Severe dengue (SD) is a major cause of morbidity and mortality. To define dengue virus (DENV) target cells and immunological hallmarks of SD...
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Rational design of multi-epitope-based vaccine by exploring all dengue virus serotypes proteome: an immunoinformatic approach
Millions of people’s lives are being devastated by dengue virus (DENV), a severe tropical and subtropical illness spread by mosquitoes and other...
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Natural vertical transmission of dengue virus in Latin America and the Caribbean: highlighting its detection limitations and potential significance
Dengue continues to be a major public health concern in Latin America and the Caribbean with many countries in the region having experienced drastic...
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Serological Diagnosis of Dengue
A reliable and specific diagnosis is imperative in viral diagnosis, both for clinical management and surveillance, and to ensure that early treatment...
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Catastrophic tumefactive acute disseminated encephalomyelitis in patient with dengue virus: a case report
Tumefactive demyelinating lesions (TDL) are a rare occurrence among inflammatory demyelinating diseases of the central nervous system, distinguished...
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Dengue and COVID-19: two sides of the same coin
BackgroundMany countries in Asia and Latin America are currently facing a double burden of outbreaks due to dengue and COVID-19. Here we discuss the...
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Temperature affects viral kinetics and vectorial capacity of Aedes aegypti mosquitoes co-infected with Mayaro and Dengue viruses
BackgroundIncreasing global temperatures and unpredictable climatic extremes have contributed to the spread of vector-borne diseases. The mosquito Aed...
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Dengue virus 3 genotype I (GI) lineage 1 (L1) isolates elicit differential cytopathic effect with syncytium formation in human glioblastoma cells (U251)
BackgroundDengue virus (DENV) is a Flaviviridae member classified into four antigenically distinct serotypes (DENV 1, 2, 3, and 4) and further...
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In Vitro Cytokine Production by Dengue-Infected Human Monocyte-Derived Dendritic Cells
Despite many advances on the understanding of dengue pathogenesis in the last decades, some questions remained to be clarified. The virulence of the...
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Blood glucose promotes dengue virus infection in the mosquito Aedes aegypti
BackgroundDengue fever is the most rapidly spreading mosquito-borne viral disease globally. More than 2.5 billion people live in dengue-endemic...
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Effects of the source of information and knowledge of dengue fever on the mosquito control behavior of residents of border areas of Yunnan, China
BackgroundStrengthening the mosquito control measures undertaken by residents of an area where dengue fever is present can significantly decrease the...
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Dengue fever presenting as acute cerebellar ataxia: Case report and literature review
Dengue fever has been associated with several neurological complications, cerebellar involvement being among the rarest of them. Here, we describe...
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Evaluation of the extended efficacy of the Dengvaxia vaccine against symptomatic and subclinical dengue infection
More than half of the world’s population lives in areas at risk for dengue virus infection. A vaccine will be pivotal to controlling spread, however,...
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Identification and validation of ferroptosis-related genes in patients infected with dengue virus: implication in the pathogenesis of DENV
Ferroptosis, an iron-dependent form of regulated cell death, has been associated with many virus infections. However, the role of ferroptosis in...
