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Bacterial ventriculoperitoneal shunt infections: changing trends in antimicrobial susceptibility, a 7-year retrospective study from Pakistan
BackgroundVentriculoperitoneal (VP) shunt infections in adults represent a severe complication and make treatment more challenging. Therefore, drug...
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Cephalosporins
After the success of the penicillins, the next logical development in antibiotic therapy was the discovery of the cephalosporins. These agents were...
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Staphylococcus
The genus Staphylococcus consists of 61 recognised species, most of which are animal pathogens or commensals. The bacteria belonging to this genus...
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Adjuvant Molecules/Compounds in Combating Bacterial Resistance
Historically, one of the major challenges before humans has been the emergence of mutated microbial pathogens. The current covid pandemic is an...
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Molecular modeling of the phosphoglycerate kinase and fructose-bisphosphate aldolase proteins from Candida glabrata and Candida albicans
Candida species are considered one of the most common fungal pathogens affecting humans. The first colonization stage of these pathogens is based on...
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Comparison of Survival and Clinical Profile of Adults with COVID-19 Hospitalized in Two Clinics in Medellín, Colombia
Purpose of ReviewThis study compares the survival and clinical profile of hospitalized adults with COVID-19 in two clinics in the city of Medellín,...
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An interdisciplinary student-led multifaceted intervention addressing overuse of broad-spectrum antibiotics for patients with penicillin allergies
BackgroundThough 15% of hospitalized patients have a documented penicillin (PCN) allergy, fewer than 1% have an IgE-mediated reaction that...
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Clinical and microbiological characterization of Aerococcus urinae bacteraemias at Helsinki metropolitan area, Finland
Our objective was to assess the incidence of bacteraemic Aerococcus urinae cases at Helsinki metropolitan area, Finland, from a 6-year study period...
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Evaluation of the liquid colony for identification and antimicrobial susceptibility testing directly from positive blood cultures
BackgroundSepsis represents a time-sensitive disease requiring early therapeutical intervention to avoid adverse patient outcomes. Rapid...
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Antimicrobial Resistance
The discovery and development of antibiotics radically changed the treatment of bacterial infections and saved millions of lives. However, the...
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Antimicrobial Resistance Traits and Resistance Mechanisms in Bacterial Pathogens
Antimicrobial resistance is one of the most urgent health crises in the twenty-first century. Multiple factors including population explosion,...
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Class D Type Beta-Lactamases
Among various β-lactam hydrolyzing enzymes, classified from group A to D, the most genetically as well as biochemically diverse is the class D...
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Prevalence of Extended Spectrum Beta Lactamase (ESBL)-Producing E. coli: A Systematic Overview
The introduction and widespread transmission of Escherichia coli that produces extended-spectrum β-lactamases (ESBLs) pose an extreme task in...
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Prevalence of Extended Spectrum Beta Lactamase (ESBL)-Producing E. coli: A Systematic Overview
The introduction and widespread transmission of Escherichia coli that produces extended-spectrum β-lactamases (ESBLs) pose an extreme task in...
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Impact of Obesity on Hepatic Drug Clearance: What are the Influential Variables?
Drug clearance in obese subjects varies widely among different drugs and across subjects with different severity of obesity. This study investigates...
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Overcoming Antibiotic Resistance: New Perspectives
Background The exponential increase of infections due to multidrug-resistant (MDR) bacteria both in hospitals and in the community has lead to...