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Electromechanical Response of Mesenteric Ischemia Defined Through Simultaneous High-Resolution Bioelectrical and Video Map**
Intestinal motility is governed in part by bioelectrical slow-waves and spike-bursts. Mesenteric ischemia is a substantial clinical challenge, but...
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Introduction to Parasitic Helminthes and Cestoda
Subkingdom Metazoa belongs to the Kingdom Animalia. The members of the metazoa are multicellular animals and consist of tissues, organs and systems.... -
Fiber photometry in striatum reflects primarily nonsomatic changes in calcium
Fiber photometry enables recording of population neuronal calcium dynamics in awake mice. While the popularity of fiber photometry has grown in...
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Current and future strategies against cutaneous parasites
Cutaneous parasites are identified by their specific cutaneous symptoms which are elicited based on the parasite’s interactions with the host....
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The Social and Economic Impact of Neglected Tropical Diseases in Sub-Saharan Africa
NTDs are characterised by several factors, the most common of which is poverty. It is estimated that the disease costs develo** countries the... -
Independent inhibitory control mechanisms for aggressive motivation and action
Social behaviors often consist of a motivational phase followed by action. Here we show that neurons in the ventromedial hypothalamus ventrolateral...
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DNA barcoding of blackflies (Diptera: Simuliidae) as a tool for species identification and detection of hidden diversity in the eastern regions of Spain
BackgroundBlackflies have negative impact on public and animal health due to the haematophagous habit of females. In recent times, in some regions in...
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Onchocerciasis drug development: from preclinical models to humans
Twenty diseases are recognized as neglected tropical diseases (NTDs) by World Health Assembly resolutions, including human filarial diseases. The end...
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Lymphatic and Tissue Filariasis
The range and burden of neglected tropical diseases, many of which are helminth-derived, remains enormous. Infections are rampant in poor districts,... -
Wide-Field Optical Imaging in Mouse Models of Ischemic Stroke
Functional neuroimaging is a powerful tool for evaluating how local and global brain circuits evolve after focal ischemia and how these changes... -
State and rate-of-change encoding in parallel mesoaccumbal dopamine pathways
The nervous system uses fast- and slow-adapting sensory detectors in parallel to enable neuronal representations of external states and their...
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A cryptic species of Onchocerca (Nematoda: Onchocercidae) in blackflies (Simulium spp.) from southern California, USA
BackgroundEntomological surveillance for pathogens based on molecular screening of putative arthropod vectors such as blackflies (Diptera:...
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Individuals living in an onchocerciasis focus and treated three-monthly with ivermectin develop fewer new onchocercal nodules than individuals treated annually
BackgroundLittle information is available on the effect of ivermectin on the third- and fourth-stage larvae of Onchocerca volvulus . To assess a...
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Spatiotemporally heterogeneous coordination of cholinergic and neocortical activity
Variation in an animal’s behavioral state is linked to fluctuations in brain activity and cognitive ability. In the neocortex, state-dependent...
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Modelling the impact of larviciding on the population dynamics and biting rates of Simulium damnosum (s.l.): implications for vector control as a complementary strategy for onchocerciasis elimination in Africa
BackgroundIn 2012, the World Health Organization set goals for the elimination of onchocerciasis transmission by 2020 in selected African countries....
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Rapid fluctuations in functional connectivity of cortical networks encode spontaneous behavior
Experimental work across species has demonstrated that spontaneously generated behaviors are robustly coupled to variations in neural activity within...
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A dynamic sequence of visual processing initiated by gaze shifts
Animals move their head and eyes as they explore the visual scene. Neural correlates of these movements have been found in rodent primary visual...
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Biodiversity, seasonal abundance, and distribution of blackflies (Diptera: Simuliidae) in six different regions of Thailand
BackgroundBlackflies are an important medical and veterinary group of small blood-sucking insects. Ninety-three blackfly species have been reported...
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Neonicotinoids: mechanisms of systemic toxicity based on oxidative stress-mitochondrial damage
Neonicotinoids are the most widely used pesticides in the world. However, research studies have shown that it can affect the cognitive abilities and...
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Entomological assessment of the transmission following recrudescence of onchocerciasis in the Comoé Valley, Burkina Faso
BackgroundOnchocerciasis, or river blindness, is a dermal filariasis caused by infection with the nematode parasite Onchocerca volvulus , transmitted...