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Identification and validation of an E2F-related gene signature for predicting recurrence-free survival in human prostate cancer
BackgroundIt is well-established that biochemical recurrence is detrimental to prostate cancer (PCa). In the present study, we explored the...
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Vaginal microbial profile of cervical cancer patients receiving chemoradiotherapy: the potential involvement of Lactobacillus iners in recurrence
The vaginal microbiome is an immune defense against reproductive diseases and can serve as an important biomarker for cervical cancer. However, the...
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18F-Fluciclovine PET/CT performance in biochemical recurrence of prostate cancer: a systematic review
BackgroundA systematic literature review of the performance of 18 Fluorine-fluciclovine PET/CT for imaging of men with recurrent prostate cancer was...
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High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer
BackgroundProstate cancer (PCa) is the most frequent cancer in men. The prognosis of PCa is heterogeneous with many clinically indolent tumors and...
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PTEN and P-4E-BP1 might be associated with postoperative recurrence of rectal cancer patients undergoing concurrent radiochemotherapy
BackgroundLocal recurrence after surgery and radiochemotherapy seriously affects the prognosis of locally advanced rectal cancer (LARC) patients....
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Ultrasound-based nomogram to predict the recurrence in papillary thyroid carcinoma using machine learning
Background and aimsThe recurrence of papillary thyroid carcinoma (PTC) is not unusual and associated with risk of death. This study is aimed to...
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An 18-gene signature of recurrence-associated endothelial cells predicts tumor progression and castration resistance in prostate cancer
BackgroundThe prognostic and therapeutic implications of endothelial cells (ECs) heterogeneity in prostate cancer (PCa) are poorly understood.
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Association between surgical extent and recurrence in unilateral intermediate- to high-risk papillary thyroid cancer
BackgroundGuidelines recommend total thyroidectomy (TT) to facilitate radioactive ablation and serological follow-up for intermediate- to high-risk...
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Tumor immune contexture predicts recurrence after prostatectomy and efficacy of androgen deprivation and immunotherapy in prostate cancer
BackgroundProstate cancer is one of the most common cancers in men with notable interpatient heterogeneity. Implications of the immune...
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Prostate-specific membrane antigen expression predicts recurrence of papillary thyroid carcinoma after total thyroidectomy
BackgroundProstate-specific membrane antigen (PSMA) overexpression has been observed in the endothelial neovasculature of several solid malignancies....
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Development and validation of prediction models for papillary thyroid cancer structural recurrence using machine learning approaches
BackgroundAlthough papillary thyroid cancer (PTC) patients are known to have an excellent prognosis, up to 30% of patients experience disease...
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MRI lesion size is more important than the number of positive biopsy cores in predicting adverse features and recurrence after radical prostatectomy: implications for active surveillance criteria in intermediate-risk patients
IntroductionTo determine associations between prostate cancer (PCa) tumor burden measured on biopsy or multiparametric magnetic resonance imaging...
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Early and late recurrence after hepatectomy in patients with low-level HBV-DNA hepatocellular carcinoma under antiviral therapy
BackgroundAntiviral therapy has been shown to benefit long-term survival after curative hepatectomy in patients with hepatitis B virus...
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A randomized phase 2 study of bicalutamide with or without metformin for biochemical recurrence in overweight or obese prostate cancer patients (BIMET-1)
BackgroundMetformin may have anticancer effects that are independent of its hypoglycemic effects. Retrospective studies have shown that metformin use...
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Phosphorylation of β-catenin at Serine552 correlates with invasion and recurrence of non-functioning pituitary neuroendocrine tumours
Non-functioning pituitary tumours (NF-PitNETs) are common intracranial benign neoplasms that can exhibit aggressive behaviour by invading...
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Role of myeloid-derived suppressor cells in tumor recurrence
The establishment of primary tumor cells in distant organs, termed metastasis, is the principal cause of cancer mortality and is a crucial...
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High-volume prostate biopsy core involvement is not associated with an increased risk of cancer recurrence following 5-fraction stereotactic body radiation therapy monotherapy
PurposePercentage of positive cores involved on a systemic prostate biopsy has been established as a risk factor for adverse oncologic outcomes and...
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Hepatocyte SGK1 activated by hepatic ischemia-reperfusion promotes the recurrence of liver metastasis via IL-6/STAT3
BackgroundLiver metastasis is the leading cause of death in patients with colorectal cancer (CRC). Surgical resection of the liver metastases...
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Liquid biopsy for monitoring of tumor dormancy and early detection of disease recurrence in solid tumors
Cancer is one of the three leading causes of death worldwide. Even after successful therapy and achieving remission, the risk of relapse often...
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Development and validation of web calculators to predict early recurrence and long-term survival in patients with duodenal papilla carcinoma after pancreaticoduodenectomy
BackgroundDuodenal papilla carcinoma (DPC) is prone to relapse even after radical pancreaticoduodenectomy (PD) (including robotic, laparoscopic and...
