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Successful treatment of ceftazidime/avibactam combined with aztreonam in the NDM-producing Klebsiella pneumoniae bloodstream and intestinal infections in a NK/T lymphoma patient with agranulocytosis during autologous hematopoietic stem cell transplantation: a case report
New Delhi metallo-beta-lactamase (NDM)-producing Klebsiella pneumoniae is increasingly reported worldwide. Clinicians face significant challenges in...
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Regeneration of joint surface defects by transplantation of allogeneic cartilage: application of iPS cell-derived cartilage and immunogenicity
BackgroundBecause of its poor intrinsic repair capacity, articular cartilage seldom heals when damaged.
Main bodyRegenerative treatment is expected...
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Changes in tuberculosis risk after transplantation in the setting of decreased community tuberculosis incidence: a national population-based study, 2008–2020
BackgroundTransplant recipients are immunocompromised and vulnerable to develo** tuberculosis. However, active tuberculosis incidence is rapidly...
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Real-world data of long-term survival in patients with T-cell lymphoma who underwent stem cell transplantation
This study aimed to identify the benefits of autologous-stem cell transplantation (auto-SCT) and allogeneic-SCT (allo-SCT) in patients with...
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“What I wanted to do was build myself back up and prepare”: qualitative findings from the PERCEPT trial of prehabilitation during autologous stem cell transplantation in myeloma
BackgroundThe addition of qualitative methodology to randomised controlled trials evaluating complex interventions allows better understanding of...
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Novel artificial nerve transplantation of human iPSC-derived neurite bundles enhanced nerve regeneration after peripheral nerve injury
BackgroundSevere peripheral nerve damage always requires surgical treatment. Autologous nerve transplantation is a standard treatment, but it is not...
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Safety and feasibility of autologous olfactory ensheathing cell and bone marrow mesenchymal stem cell co-transplantation in chronic human spinal cord injury: a clinical trial
Study designThis is a phase I clinical trial.
ObjectivesOur objective was to assess the safety and feasibility of autologous mucosal olfactory...
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Polydactyly-derived allogeneic chondrocyte cell-sheet transplantation with high tibial osteotomy as regenerative therapy for knee osteoarthritis
Allogeneic cell therapies are not fully effective in treating osteoarthritis of the knee (OAK). We recently reported that transplantation of...
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Age-adjusted high-dose chemotherapy followed by autologous stem cell transplantation or conventional chemotherapy with R-MP as first-line treatment in elderly primary CNS lymphoma patients – the randomized phase III PRIMA-CNS trial
BackgroundOlder primary central nervous system lymphoma (PCNSL) patients have an inferior prognosis compared to younger patients because available...
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Survey of HCMV in allogenic and autologous stem cell transplantation by real-time PCR in Kermanshah, west of Iran
IntroductionHuman Cytomegalovirus (HCMV) is the most important viral pathogen in people undergoing bone marrow transplantation (BMT). HCMV detection...
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Automating iPSC generation to enable autologous photoreceptor cell replacement therapy
BackgroundInherited retinal degeneration is a leading cause of incurable vision loss in the developed world. While autologous iPSC mediated...
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Therapeutic Strategies to Potentially Cure Multiple Sclerosis: Insights into the Mechanisms of Autologous Hematopoietic Stem Cell Transplantation
Immune reconstitution therapies (IRTs) offer the potential to induce long-lasting remission or even permanent absence of disease activity in patients...
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Mitochondrial transplantation as a novel therapeutic strategy for cardiovascular diseases
Cardiovascular disease (CVD) is the leading cause of noncommunicable disease-related death worldwide, and effective therapeutic strategies against...
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Therapeutic potential of mitochondrial transplantation in modulating immune responses post-cardiac arrest: a narrative review
BackgroundMitochondrial transplantation (MTx) has emerged as a novel therapeutic strategy, particularly effective in diseases characterized by...
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Tolerance and Transplantation Immunology
In this chapter, we will first discuss about the impact and mechanisms of immunological tolerance, which is differentiated into central and...
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Characteristics and outcomes of children, adolescents and young adults with relapsed/refractory non-hodgkin lymphoma undergoing autologous stem cell transplant
BackgroundThere is paucity of data regarding outcomes of children, adolescents and young adults (CAYA) patients with non-Hodgkin lymphoma (NHL)...
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Sequential CD19/22 CAR T-cell immunotherapy following autologous stem cell transplantation for central nervous system lymphoma
Chimeric antigen receptor (CAR) T-cell immunotherapy following autologous stem cell transplantation (ASCT) is a promising method for refractory or...
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Mitochondrial Transportation, Transplantation, and Subsequent Immune Response in Alzheimer’s Disease: An Update
Alzheimer’s disease (AD) is a devastating neurodegenerative disease characterized by memory impairment and a progressive decline in cognitive...
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Outcomes of patients with multiple myeloma and 1q gain/amplification receiving autologous hematopoietic stem cell transplant: the MD Anderson cancer center experience
The prognostic impact of additional copies of chromosome 1q (1q + ) on outcomes of newly-diagnosed multiple myeloma (NDMM) patients undergoing...
