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Trajectories of alcohol consumption during life and the risk of develo** breast cancer
BackgroundWhether there are lifetime points of greater sensitivity to the deleterious effects of alcohol intake on the breasts remains inconclusive.
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Consuming oral cannabidiol prior to a standard alcohol dose has minimal effect on breath alcohol level and subjective effects of alcohol
RationaleCannabidiol (CBD) is found in the cannabis plant and has garnered attention as a potential treatment for alcohol use disorder (AUD). CBD...
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The impact of heavy alcohol consumption on cognitive impairment in young old and middle old persons
BackgroundDementia indicates a significant disease burden worldwide with increased population aging. This study aimed to investigate the impact of...
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An overview of current advances in perinatal alcohol exposure and pathogenesis of fetal alcohol spectrum disorders
The adverse use of alcohol is a serious global public health problem. Maternal alcohol consumption during pregnancy usually causes prenatal alcohol...
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Psilocybin prevents reinstatement of alcohol seeking by disrupting the reconsolidation of alcohol-related memories
BackgroundFor most psychiatric conditions, including alcohol use disorder (AUD), FDA-approved pharmacological treatments are limited and their...
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Validating biomarkers and models for epigenetic inference of alcohol consumption from blood
BackgroundInformation on long-term alcohol consumption is relevant for medical and public health research, disease therapy, and other areas....
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Alcohol and the Cerebellum
Alcohol (EtOH) is a socially accepted and widely used psychoactive compound, derived from the fermentation/distillation of various plant sugars....
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Biomarkers of Alcohol Toxicity
The aim of this review is to explore the current understanding of the mechanisms and course of alcohol intoxication, in particular by discussing the...
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Alcohol and the vasculature: a love-hate relationship?
Alcohol consumption is a leading risk factor and increases the risk of liver diseases, cancers, tuberculosis, and injuries. The relationship between...
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Federated Analysis in COINSTAC Reveals Functional Network Connectivity and Spectral Links to Smoking and Alcohol Consumption in Nearly 2,000 Adolescent Brains
With the growth of decentralized/federated analysis approaches in neuroimaging, the opportunities to study brain disorders using data from multiple...
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Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats
We recently reported that intraperitoneal injection of 7,8-dihydroxyflavone (7,8-DHF), a brain-derived neurotrophic factor-mimicking small compound,...
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Endpoints for Pharmacotherapy Trials for Alcohol Use Disorder
Alcohol use disorder (AUD) is a debilitating disorder, yet currently approved pharmacotherapies to treat AUD are under-utilized. The three...
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Subjective response to alcohol in young adults with bipolar disorder and recent alcohol use: a within-subject randomized placebo-controlled alcohol administration study
Limited data exists on mechanisms contributing to elevated risk for alcohol use disorder (AUD) in bipolar disorder. Variation in subjective response...
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Examining the association between opium use, cigarette smoking and alcohol consumption with the liver enzyme levels in a population-based study: Fasa Persian cohort data
ObjectivesOpium use, cigarette smoking, and alcohol consumption are serious health problems in many countries including Iran. The present study aimed...
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Subthalamic high-frequency deep brain stimulation reduces addiction-like alcohol use and the possible negative influence of a peer presence
RationaleThe immediate social context significantly influences alcohol consumption in humans. Recent studies have revealed that peer presence could...
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The ad-libitum taste test as measure of momentary alcohol use in the laboratory: an investigation of construct validity and confounding factors
RationaleThe ad-libitum taste test is a widely used covert measure of motivation to consume alcohol in the laboratory. However, studies on its...
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Sex differences in binge alcohol drinking and the behavioral consequences of protracted abstinence in C57BL/6J mice
BackgroundBinge alcohol drinking is a risk factor linked to numerous disease states including alcohol use disorder (AUD). While men binge drink more...
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Drinking frequency matters: links between consumption pattern and implicit/explicit attitudes towards alcohol
RationaleAttitudes towards alcohol constitute a central factor to predict future consumption. Previous studies showed that young adults with risky...
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Evaluation of alcohol use behavior among patients cured through HCV elimination program in Georgia
ObjectiveThe objective of the study was to understand the role of self-reported drinking behavior on liver health after achieving sustained viral...