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Metabolic parameters of sequential 18F-FDG PET/CT predict overall survival of esophageal cancer patients treated with (chemo-) radiation
BackgroundTo evaluate the prognostic value of metabolic parameters of pre-treatment and interim 18F-fluorodeoxyglucose (FDG) positron emission...
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Clozapine-Induced Chemogenetic Neuromodulation Rescues Post-Stroke Deficits After Chronic Capsular Infarct
Long-term disabilities induced by stroke impose a heavy burden on patients, families, caregivers, and public health systems. Extensive studies have...
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Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer’s subjects?
BackgroundType 2 diabetes is a risk factor for Alzheimer’s disease (AD), and AD brain shows impaired insulin signalling. The role of peripheral...
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Association of peripheral immunity with cognition, neuroimaging, and Alzheimer’s pathology
BackgroundNeuroinflammation has been considered to be a driving force of Alzheimer’s disease. However, the association between peripheral immunity...
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Salivary lactoferrin is associated with cortical amyloid-beta load, cortical integrity, and memory in aging
BackgroundAging is associated with declining protective immunity and persistent low-grade inflammatory responses, which significantly contribute to...
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Does baseline [18F] FDG-PET/CT correlate with tumor staging, response after neoadjuvant chemoradiotherapy, and prognosis in patients with rectal cancer?
Background[18F] fluorodeoxyglucose positron emission tomography/computed tomography ([18F] FDG-PET/CT) may be used for tumor staging and prognosis in...
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A Review of Hypoxia Imaging Using 18F-Fluoromisonidazole Positron Emission Tomography
Tumor hypoxia is an essential factor related to malignancy, prognosis, and resistance to treatment. Positron emission tomography (PET) is a modality...
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Prediction of pathological response following neoadjuvant chemotherapy in patients with muscle-invasive bladder cancer: the PRE-PREVENCYS trial
BackgroundThe recommended treatment for patients with non-metastatic muscle-invasive bladder cancer (MIBC) is neoadjuvant chemotherapy (NAC) and...
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Diagnostic accuracy and clinical value of [68Ga]Ga-FAPI-46 PET/CT for staging patients with ovarian cancer: study protocol for a prospective clinical trial
Background[ 18 F]Fluorodeoxyglucose ([ 18 F]FDG) positron emission tomography (PET) is recommended during diagnostic work-up for ovarian cancer;...
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[18F]FDG-PET/CT-based risk stratification in women with locally advanced uterine cervical cancer
Background[ 18 F]FDG-PET/CT is used for staging and treatment planning in patients with locally advanced cervical cancer (LACC). We studied if a...
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Relationship Between Reactive Astrocytes, by [18F]SMBT-1 Imaging, with Amyloid-Beta, Tau, Glucose Metabolism, and TSPO in Mouse Models of Alzheimer’s Disease
Reactive astrocytes play an important role in the development of Alzheimer’s disease (AD). Here, we aimed to investigate the temporospatial...
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The therapeutic effect of a novel GAPDH inhibitor in mouse model of breast cancer and efficacy monitoring by molecular imaging
BackgroundBreast cancer is a serious threat to women’s health with high morbidity and mortality. The development of more effective therapies for the...
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Survival time prediction in patients with high-grade serous ovarian cancer based on 18F-FDG PET/CT- derived inter-tumor heterogeneity metrics
BackgroundThe presence of heterogeneity is a significant attribute within the context of ovarian cancer. This study aimed to assess the predictive...
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Biomarkers in Renal Cell Carcinoma
Renal cell carcinoma (RCC) constitutes 90% of all kidney tumours. It also accounts for higher mortality rates of up to 30–40% as compared to prostate...
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Detection of HER2 expression using 99mTc-NM-02 nanobody in patients with breast cancer: a non-randomized, non-blinded clinical trial
Background99m Tc radiolabeled nanobody NM-02 ( 99m Tc-NM-02) is a novel single photon emission computed tomography (SPECT) probe with a high affinity...
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Radiotracers, Positron Emission Tomography Imaging and Traumatic Brain Injury
Over the last few decades, the expanded application of nuclear medicine has produced extensive knowledge of the pathophysiological processes...
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PTPRH promotes the progression of non-small cell lung cancer via glycolysis mediated by the PI3K/AKT/mTOR signaling pathway
BackgroundThe protein tyrosine phosphatase H receptor (PTPRH) is known to regulate the occurrence and development of pancreatic and colorectal...
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Predictive value of CT and 18F-FDG PET/CT features on spread through air space in lung adenocarcinoma
BackgroundLung adenocarcinoma, a leading cause of cancer-related mortality, demands precise prognostic indicators for effective management. The...
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Associations between detectable circulating tumor DNA and tumor glucose uptake measured by 18F-FDG PET/CT in early-stage non-small cell lung cancer
BackgroundThe low level of circulating tumor DNA (ctDNA) in the blood is a well-known challenge for the application of liquid biopsies in early-stage...
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[18F]-FDopa positron emission tomography imaging in corticobasal syndrome
PurposeFirst, to investigate the patterns of [ 18 F]-FDOPA positron emission tomography imaging in corticobasal syndrome using visual and...
