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Resistance to Targeted Therapy in Breast Cancer
The discoveries of breast cancer molecular subtypes and their deregulated pathways have given rise to the emergence of potential therapeutic targets...
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Aptamers as an approach to targeted cancer therapy
Conventional cancer treatments can cause serious side effects because they are not specific to cancer cells and can damage healthy cells. Aptamers...
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Antibody-displaying extracellular vesicles for targeted cancer therapy
Extracellular vesicles (EVs) function as natural delivery vectors and mediators of biological signals across tissues. Here, by leveraging these...
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Signaling pathways in liver cancer: pathogenesis and targeted therapy
Liver cancer remains one of the most prevalent malignancies worldwide with high incidence and mortality rates. Due to its subtle onset, liver cancer...
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The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance
In this study, the impact of the apolipoprotein B mRNA-editing catalytic subunit-like (APOBEC) enzyme APOBEC3B (A3B) on epidermal growth factor...
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Cancer Therapy
Current cancer therapy is based on surgery, radiotherapy, chemotherapy, and immunotherapy, often administered in combination. Cytotoxic chemotherapy...
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Role of Exosomes in Cancer and Aptamer-Modified Exosomes as a Promising Platform for Cancer Targeted Therapy
Exosomes are increasingly recognized as important mediators of intercellular communication in cancer biology. Exosomes can be derived from cancer...
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Recent advances in non-small cell lung cancer targeted therapy; an update review
Lung cancer continues to be the leading cause of cancer-related death worldwide. In the last decade, significant advancements in the diagnosis and...
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Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer
Breast cancer is the second leading cause of death for women worldwide. The heterogeneity of this disease presents a big challenge in its therapeutic...
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Novel Approaches in Cancer Treatment: Tumor Targeted Therapy
Phytochemicals and their derivatives are of great attention in the treatment of cancer. The use of phytochemicals is recognized being a powerful...
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Functionalized Nanoparticles for Cancer Therapy
Chemotherapy is a standard cancer therapy but it has adverse effects because it sometimes fails to deliver therapeutic drugs to tumour cells in safe...
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Cancer-associated fibroblasts: a versatile mediator in tumor progression, metastasis, and targeted therapy
Tumor microenvironment (TME) has been demonstrated to play a significant role in tumor initiation, progression, and metastasis. Cancer-associated...
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PROTAC’ing oncoproteins: targeted protein degradation for cancer therapy
Molecularly targeted cancer therapies substantially improve patient outcomes, although the durability of their effectiveness can be limited....
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Transcriptional regulation and post-translational modifications in the glycolytic pathway for targeted cancer therapy
Cancer cells largely rely on aerobic glycolysis or the Warburg effect to generate essential biomolecules and energy for their rapid growth. The key...
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Recent Update on Nanocarrier(s) as the Targeted Therapy for Breast Cancer
Despite ongoing advances in cancer therapy, the results for the treatment of breast cancer are not satisfactory. The advent of nanotechnology...
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Enhancing treatment strategies for small bowel cancer: a clinical review of targeted therapy and immunotherapy approaches
Small bowel cancer (SBC) is a rare and aggressive disease with a poor prognosis, necessitating the exploration of novel treatment approaches. This...
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Antibody-Functionalized Nanoparticles for Targeted Drug Delivery in Cancer Therapy
Targeted therapies using nanoparticles have been proposed to address some drawbacks of conventional chemotherapy. In the last two decades, surface...
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Resistance to Endocrine Therapy in Breast Cancer
The foremost cause of female deaths is due to breast cancer. The most frequent type of breast cancer is hormone-dependent breast cancer, being either...
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Nanoparticles in Cancer Therapy
In the realm of cancer therapy, nanoparticles have emerged as a pioneering avenue, ushering in a remarkable journey filled with breakthroughs and...
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Personalized matched targeted therapy in advanced pancreatic cancer: a pilot cohort analysis
Despite progress, 2-year pancreatic cancer survival remains dismal. We evaluated a biomarker-driven, combination/N-of-one strategy in 18 patients...
