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Revisiting the Effect of Aging on the Transport of Molecules through the Skin
Both intrinsic and extrinsic aging lead to a series of morphological changes in the skin including the flattening of the dermal–epidermal junction,...
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Biology of Sarcoptes scabiei and Its Relevance to Human Scabies: Clinical Symptoms, Treatment, and Management
Sarcoptes scabiei var. hominis is a mite with an oval tortoise-like-shaped body bearing four pairs of legs. Human scabies starts when a fertilized...
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Delayed Expression of Both GABABR1 and GABABR2 Subunits in Murine Hippocampal Dentate Gyrus After a Single Systemic Injection of Trimethyltin
Trimethyltin (TMT) has been used as a cytotoxin to neurons rather than glial cells in the mammalian hippocampus. The systemic administration of TMT...
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Lecture 3: The Integument
The skin, hair, nails, glands and several specialised receptors make up the integumentary system.
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Effects of Suppression of Glycolysis on the Ultrastructure of Giant Hippocampal Synapses
Suppression of glycolysis in the hippocampal formation was induced in rats by daily administration of 2-deoxy-D-glucose into the lateral ventricles...
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3D Bioprinting of Skin Tissue Model
The challenges and potential of using tissue engineering and regenerative medicine to create functional skin tissue constructs. While traditional...
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Topically Applied Products
This chapter reviews the basic concepts involved in topically applied pharmaceuticals for local delivery as well as transdermal delivery. The...
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Transient Receptor Potential Vanilloid 6 Modulates Aberrant Axonal Sprouting in a Mouse Model of Pilocarpine-Induced Epilepsy
Transient receptor potential vanilloid 6 (TRPV6) is a highly selective calcium-ion channel that belongs to the TRPV family. TRPV6 is widely...
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A culture model for the assessment of phenylalanine neurotoxicity in phenylketonuria
ObjectivePhenylketonuria (PKU) is caused by a specific mutation of the phenylalanine hydroxylase (PAH) gene. The deficiency of PAH results in high...
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Ultraweak Photon Emission from the Human Body in Relation to Anatomy and Histology
Ultraweak photon emission (UPE) from a human body has been demonstrated but it is not exactly known where this light comes from. Neither studies...
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Enhancement strategies for transdermal drug delivery systems: current trends and applications
Transdermal drug delivery systems have become an intriguing research topic in pharmaceutical technology area and one of the most frequently developed...
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Solar Radiation and Phototoxicity of Cosmetics: Avenues of In Vitro Skin Models
Skin is the body’s largest organ, performing several critical functions, including photoprotection and thermoregulation. The skin comprises three...
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Nanocarriers in Transdermal Drug Delivery
The transdermal route of drug administration is the most widely used route for systemic administration of drugs due to the convenience and...
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Aquaporins in Skin
The skin is the largest organ of our body and plays a protective role against the external environment. The skin functions as a mechanical and water...
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Immunohistochemical field parcellation of the human hippocampus along its antero-posterior axis
The primate hippocampus includes the dentate gyrus, cornu ammonis (CA), and subiculum. CA is subdivided into four fields (CA1-CA3, plus CA3h/hilus of...
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Effect of chemical penetration enhancers on the transdermal delivery of olanzapine in human skin in vitro
This research study involves the development of an olanzapine (OLZ) formulation using various chemical penetration enhancers (CPEs) for transdermal...
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Different changes in pre- and postsynaptic components in the hippocampal CA1 subfield after transient global cerebral ischemia
To date, ischemia-induced damage to dendritic spines has attracted considerable attention, while the possible effects of ischemia on presynaptic...
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Laser-mediated Solutions: Breaking Barriers in Transdermal Drug Delivery
Skin diseases pose challenges in treatment due to the skin’s complex structure and protective functions. Topical drug delivery has emerged as a...
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Scabies-Associated Microbiota
Globally, scabies causes substantial morbidity and mortality. In the tropics, scabies promotes opportunistic bacterial infections, leading to...
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Integumentary System
The skin covers the body with the superficial epidermis, made of epithelial tissue, and the deeper dermis, containing much connective tissue. Under...