Search
Search Results
-
C57Bl/6N mice have an attenuated lung inflammatory response to dsRNA compared to C57Bl/6J and BALB/c mice
BackgroundLower respiratory infections caused by ssRNA viruses are a major health burden globally. Translational mouse models are a valuable tool for...
-
Sex-based differences in natural killer T cell-mediated protection against diet-induced steatohepatitis in Balb/c mice
BackgroundMetabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in Western countries, evolving into metabolic...
-
Alterations of plasma circulating microRNAs in BALB/c mice with Toxocara canis visceral and cerebral larva migrans
BackgroundHuman toxocariasis is a neglected parasitic disease characterised by the syndromes visceral, cerebral, and ocular larva migrans. This...
-
Common and Specific Effects of Selank, Noopept, and Semax on the Glycine Site of the NMDA Receptor in BALB/c and C57Bl/6 Mice Brains
Abstract —We have examined the effects of the nootropic peptides Selank (300 mg/kg), Noopept (1 mg/kg), and Semax (0.6 mg/kg) after subchronic...
-
Effect of chronic low-dose treatment with chitooligosaccharides on microbial dysbiosis and inflammation associated chronic ulcerative colitis in Balb/c mice
The study aimed to investigate the potential of low dose chitooligosaccharide (COS) in ameliorating dextran sodium sulfate (DSS) induced chronic...
-
Effect of Polyphenolic Composition BP-C2 on Lung Carcinogenesis Induced by Urethane in Progeny of Irradiated Male BALB/c Mice
We studied the effects of polyphenolic composition BP-C2, comprising molybdenum with lignin derivatives, on lung carcinogenesis induced by urethane...
-
Visualized Enzyme-Activated Fluorescence Probe for Accurately Detecting β-Gal in Living Cells and BALB/c Nude Mice
Colorectal cancer was one of the major malignant tumors threatening human health and β-Gal was recognized as a principal biomarker for primary...
-
Preclinical Development of a Novel Epitope-based DNA Vaccine Candidate against SARS-CoV-2 and Evaluation of Immunogenicity in BALB/c Mice
The protective efficacies of current licensed vaccines against COVID-19 have significantly reduced as a result of SARS-CoV-2 variants of...
-
Development of doxorubicin-encapsulated magnetic liposome@PEG for treatment of breast cancer in BALB/c mice
The magnetic doxorubicin-encapsulated liposome/PEG/Fe 3 O 4 (called as DOX@m-Lip/PEG) was synthesized and studied as a novel nanocarrier for the...
-
The Study of the State of Monoaminergic Systems in the Brain Structures of the Offsprings of Female BALB/c Mice at Different Stages of Formation of Autism Spectrum Disorders
Abstract —The study of the status of norepinephrine-, dopamine- and serotonergic neurotransmitter systems of BALB/C mice brain structures on 15 and 64...
-
Oral administration of DNA alginate nanovaccine induced immune-protection against Helicobacter pylori in Balb/C mice
BackgroundHelicobacter pylori (H. Pylori), is an established causative factor for the development of gastric cancer and the induction of persistent...
-
Immune Response Profiling of Cocktails of Brugia malayi Vaccine Candidates DIM-1, Calponin and Troponin 1 in BALB/c Mice
PurposeIn search of a vaccine for the control of human lymphatic filariasis (LF) caused by Wuchereria bancrofti , Brugia malayi and B. timori, we...
-
Damage to Nuclear and Mitochondrial DNA in Different Organs in Streptozotocin-Induced Diabetes Models in BALB/c Mice
Male BALB/c mice with streptozotocin-induced diabetes mellitus were used to study nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) damage using comet...
-
In silico pharmacokinetic and therapeutic evaluation of Musa acuminata peels against aluminium chloride-induced hepatotoxicity in adult BALB/c mice
East Africa ( Musa spp.), notably Musa acuminata , “Matooke” a staple and economically important food in the region. Here, 12 selected M . acuminata ...
-
Effects of Acute Swimming Stress on the Behavioral and Neurochemical Effects of Pyrazolo[C]pyridine Derivative GIZh-72 and Diazepam in BALB/c and C57BL/6 Mice
The effects of acute swimming stress (ASS) on the behavioral and neurochemical actions of a pyrazolo[C]pyridine derivative GIZh-72 (20 mg/kg, i.p.)...
-
Preparation of chitosan nanoparticle containing recombinant CD44v antigen and evaluation of its immunization capacity against breast cancer in BALB/c mice
Objective(s)Breast tumors show heterogeneity containing cancer stem cells as a small subpopulation of a tumor mass. CD44 as a cancer stem cells...
-
Zinc and Manganese Imbalances in BALB/c Mice Experimentally Infected with Leishmania (Leishmania) amazonensis
PurposeThe clinical progression of Leishmania (Leishmania) amazonensis infection depends on multiple factors, including immunological status of the...
-
Echinochrome exhibits anti-asthmatic activity through the suppression of airway inflammation, oxidative stress, and histopathological alterations in ovalbumin-induced asthma in BALB/c mice
Asthma is a chronic pulmonary disease with marked infiltrating inflammatory cells and reduced respiratory performance. Echinochrome (Ech) is a...
-
Studies on the mechanism of local and extra-intestinal tissue manifestations in AOM-DSS-induced carcinogenesis in BALB/c mice: role of PARP-1, NLRP3, and autophagy
Colitis-associated colorectal cancer (CACC) is one of the devastating complications of long-term inflammatory bowel disease and is associated with...
-
Naringenin-Zinc Oxide Nanocomposites Amalgamated Polymeric Gel Augmented Drug Delivery and Attenuated Experimental Cutaneous Candidiasis in Balb/c Mice: In Vitro and In Vivo Studies
Naringenin (NRG) inhibits the fungal 17β-hydroxysteroid dehydrogenase accountable for ergosterol synthesis in Candida albicans ( C. albicans ), a...
