Search
Search Results
-
Overcoming donor variability and risks associated with fecal microbiota transplants through bacteriophage-mediated treatments
BackgroundFecal microbiota transplantation (FMT) and fecal virome transplantation (FVT, sterile filtrated donor feces) have been effective in...
-
Diagnostic performance of an ultra-sensitive RDT and a conventional RDT in malaria mass testing, treatment and tracking interventions in southern Ghana
BackgroundApplication of numerous malaria control interventions has led to reduction in clinical malaria cases and deaths but also the realisation...
-
In situ analysis of neuronal injury and neuroinflammation during HIV-1 infection
BackgroundSince the introduction of combination antiretroviral therapy (cART) the brain has become an important human immunodeficiency virus (HIV)...
-
Microbial signatures and continuum in endometrial cancer and benign patients
BackgroundEndometrial cancer is a multifactorial disease with inflammatory, metabolic and potentially microbial cues involved in disease...
-
Amorfrutin B Compromises Hypoxia/Ischemia-induced Activation of Human Microglia in a PPARγ-dependent Manner: Effects on Inflammation, Proliferation Potential, and Mitochondrial Status
Amorfrutin B is a selective PPARγ modulator that we demonstrated to be a promising neuroprotective compound in cellular models of stroke and...
-
Double vision: 2D and 3D mosquito trajectories can be as valuable for behaviour analysis via machine learning
BackgroundMosquitoes are carriers of tropical diseases, thus demanding a comprehensive understanding of their behaviour to devise effective disease...
-
Twenty-year evolution of Leishmania infantum infection in dogs in Valdeorras (Galicia, Northwestern Spain): implication of climatic factors and preventive measures
BackgroundAbiotic factors play a significant role in the evolution of Leishmania infantum infection due to its vectorial nature. This study aims to...
-
CViewer: a Java-based statistical framework for integration of shotgun metagenomics with other omics datasets
BackgroundShotgun metagenomics for microbial community survey recovers enormous amount of information for microbial genomes that include their...
-
Differences in neutralizing antibody sensitivities and envelope characteristics indicate distinct antigenic properties of Nigerian HIV-1 subtype G and CRF02_AG
The magnitude of the HIV-1 epidemic in Nigeria is second only to the subtype C epidemic in South Africa, yet the subtypes prevalent in Nigeria...
-
Recombination of variable and host range regions of glycoprotein gp85 in different avian leukosis virus subgroup K isolates
Given the high prevalence of avian leukosis virus subgroup K (ALV-K) in chickens in China, the positive rate of ALV-K in local chickens in Henan...
-
Evaluation of an Automated Ultrafiltration System for Concentrating a Range of Viruses from Saline Waters
Pathogenic viruses in environmental water are usually present in levels too low for direct detection and thus, a concentration step is often required...
-
Dynamics of peripheral T cell exhaustion and monocyte subpopulations in neurocognitive impairment and brain atrophy in chronic HIV infection
BackgroundHIV-associated neurocognitive disorders (HAND) is hypothesized to be a result of myeloid cell-induced neuro-inflammation in the central...
-
African swine fever virus DNA is present in non-biting flies collected from outbreak farms in Romania
BackgroundAfrican swine fever (ASF) is a highly contagious and severe haemorrhagic disease of Suidae, with mortalities that approach 100 percent....
-
Effects of acetate-producing Blautia wexlerae on oxidative stress and NLRP3 inflammasome in obesity-associated male infertility
Background: Obesity-associated male infertility is a common complication of obesity and has been increasing in prevalence. Blautia wexlerae has...
-
Reduction in vertical transmission rate of bean common mosaic virus in bee-pollinated common bean plants
Vertical transmission, the transfer of pathogens across generations, is a critical mechanism for the persistence of plant viruses. The transmission...
-
BAG6 restricts pancreatic cancer progression by suppressing the release of IL33-presenting extracellular vesicles and the activation of mast cells
Recent studies reveal a critical role of tumor cell-released extracellular vesicles (EVs) in pancreatic cancer (PC) progression. However, driver...
-
Systemic treatment options for non-small cell lung cancer after failure of previous immune checkpoint inhibitors: a bayesian network meta-analysis based on randomized controlled trials
BackgroundAlthough immune checkpoint inhibitors (ICIs) have brought survival benefits to non-small cell lung cancer (NSCLC), disease progression...
-
Immune-mediated inflammatory diseases and periodontal disease: a bidirectional two-sample mendelian randomization study
BackgroundPrevious observational studies have shown a bidirectional association between immune-mediated inflammatory disorders (IMID) and periodontal...
-
Oral vaccination with a recombinant Lactobacillus plantarum expressing the Eimeria tenella rhoptry neck 2 protein elicits protective immunity in broiler chickens infected with Eimeria tenella
BackgroundChicken coccidiosis is a protozoan disease that leads to considerable economic losses in the poultry industry. Live oocyst vaccination is...
-
Driving gut microbiota enterotypes through host genetics
BackgroundPopulation stratification based on interindividual variability in gut microbiota composition has revealed the existence of several ecotypes...
