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The positive reinforcing effects of cocaine and opposite-sex social contact: roles of biological sex and estrus
RationalePreclinical studies report that drug use and social contact mutually influence the reinforcing effects of one another. Most of these studies...
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Heterogeneity in choice models of addiction: the role of context
RationaleTheories of addiction guide scientific progress, funding priorities, and policy development and ultimately shape how people experiencing or...
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Decoding the Preparation Stage of Target Shooting under Audiovisual Restricted Conditions: Investigating Neural Mechanisms Using Microstate Analysis
Shooting is a fine sport that is greatly influenced by mental state, and the neural activity of brain in the preparation stage of shooting has a...
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Menstrual variations of sleep–wake rhythms in healthy women
The ovarian steroid hormones, estrogen and progesterone, the levels of which fluctuate dynamically with the estrous cycle, alter circadian behavioral...
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Investigation of macro and micro sleep structures of first night effect in school-aged children
This study aimed to investigate the occurrence and age-related changes of the first night effect (FNE) in school-age children using both macro (sleep...
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The effect of SSRIs on unconditioned anxiety: a systematic review and meta-analysis of animal studies
RationaleSelective serotonin reuptake inhibitors (SSRIs) are the first choice of treatment for anxiety-like disorders. However, which aspects of...
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Lemborexant as a Potential Risk Factor for Sleep-Related Bruxism in a Patient with Complex Post-traumatic Stress Disorder: A Case Report
This article describes a case involving a 21-year-old woman with complex post-traumatic stress disorder (C-PTSD) who developed sleep-related bruxism...
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Update on cannabis in human sexuality
RationaleSexuality is a central aspect of being human that encompasses many facets. Cannabis, a widely used psychoactive substance, has been...
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Obstructive Sleep Apnea: Relationship Between Mild Neurocognitive Impairments and Quality of Life
Patients with obstructive sleep apnea might have neurocognitive impairments and reduced quality of life. Considering the same, this study was...
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Pulsed nicotine infusions as a model for smoking: validating a tool to explore nicotine thresholds in humans
RationaleNo previous studies examined the discriminative stimulus effects of intravenous (IV) nicotine in humans.
ObjectivesTo evaluate a pulsed IV...
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An integrated clinical approach to children at genetic risk for neurodevelopmental and psychiatric conditions: interdisciplinary collaboration and research infrastructure
BackgroundA sizeable proportion of pathogenic genetic variants identified in young children tested for congenital differences are associated with...
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Reinforcing effects of fentanyl analogs found in illicit drug markets
RationaleThe potent synthetic opioid fentanyl, and its analogs, continue to drive opioid-related overdoses. Although the pharmacology of fentanyl is...
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Unraveling psilocybin’s therapeutic potential: behavioral and neuroplasticity insights in Wistar-Kyoto and Wistar male rat models of treatment-resistant depression
RationaleOur study aimed to unravel the unknown mechanisms behind the exceptional efficacy of Psilocybin (PSI) in treating treatment-resistant...
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Nucleus accumbens ghrelin signaling controls anxiety-like behavioral response to acute stress
BackgroundAnxiety disorders are one of the most common mental disorders. Ghrelin is a critical orexigenic brain-gut peptide that regulates food...
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Cortical Generators and Connections Underlying Phoneme Perception: A Mismatch Negativity and P300 Investigation
The cortical generators of the pure tone MMN and P300 have been thoroughly studied. Their nature and interaction with respect to phoneme perception,...
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Developmental change of brain volume in Rett syndrome in Taiwan
ObjectiveRett syndrome (RTT) is characterized by neurological regression. This pioneering study investigated the effect of age on brain volume...
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Sex differences in behavior, cognitive, and physiological recovery following methamphetamine administration
Intact executive functions are required for proper performance of cognitive tasks and relies on balance of excitatory and inhibitory (E/I)...
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Static and temporal dynamic alterations of regional homogeneity in chronic insomnia: a resting-state fMRI study
To explore brain function alterations in chronic insomnia (CI). 65 CI patients and 48 healthy controls were included to analyze abnormal alterations...
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Identification of Methamphetamine Abusers Can Be Supported by EEG-Based Wavelet Transform and BiLSTM Networks
Methamphetamine (MA) is a neurological drug, which is harmful to the overall brain cognitive function when abused. Based on this property of MA,...
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Characteristics of pain empathic networks in healthy and primary dysmenorrhea women: an fMRI study
Pain empathy enables us to understand and share how others feel pain. Few studies have investigated pain empathy-related functional interactions at...
