Search
Search Results
-
Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
-
A Mouse Model of Sporadic Alzheimer’s Disease with Elements of Major Depression
After olfactory bulbectomy, animals are often used as a model of major depression or sporadic Alzheimer’s disease and, hence, the status of this...
-
Ventriculoperitoneal shunt patients and glaucoma: a cohort analysis of the NPH registry
BackgroundIdiopathic Normal Pressure Hydrocephalus (iNPH) is a chronic condition affecting the elderly. It is characterized by a triad of symptoms...
-
Investigation of macro and micro sleep structures of first night effect in school-aged children
This study aimed to investigate the occurrence and age-related changes of the first night effect (FNE) in school-age children using both macro (sleep...
-
Local activation of CB1 receptors by synthetic and endogenous cannabinoids dampens burst firing mode of reticular thalamic nucleus neurons in rats under ketamine anesthesia
The reticular thalamic nucleus (RTN) is a thin shell that covers the dorsal thalamus and controls the overall information flow from the thalamus to...
-
The role of hydrogen sulfide regulation of ferroptosis in different diseases
Ferroptosis is a programmed cell death that relies on iron and lipid peroxidation. It differs from other forms of programmed cell death such as...
-
Ellagic acid as potential therapeutic compound for diabetes and its complications: a systematic review from bench to bed
Diabetes mellitus (DM) is a worldwide-concerning disease with a rising prevalence. There are many ongoing studies aimed at finding new and effective...
-
Synthesis, cytotoxicity, anti-inflammatory, anti-metastatic and anti-oxidant activities of novel chalcones incorporating 2-phenoxy-N-arylacetamide and thiophene moieties: induction of apoptosis in MCF7 and HEP2 cells
Eight Novel chalcones were synthesized and their structures were confirmed by different spectral tools. All the prepared compounds were subjected to...
-
Perioperative complications of middle cerebral artery occlusion in rats alleviated by human umbilical cord mesenchymal stem cells
For acute ischemic stroke treatment, the limitations of treatment methods and the high incidence of perioperative complications seriously affect the...
-
Systematic Mendelian Randomization Exploring Druggable Genes for Hemorrhagic Strokes
Patients with hemorrhagic stroke have high rates of morbidity and mortality, and drugs for prevention are very limited. Mendelian randomization (MR)...
-
The effect of SSRIs on unconditioned anxiety: a systematic review and meta-analysis of animal studies
RationaleSelective serotonin reuptake inhibitors (SSRIs) are the first choice of treatment for anxiety-like disorders. However, which aspects of...
-
Fraxin alleviates oral lichen planus by suppressing OCT3-mediated activation of FGF2/NF-κB pathway
Oral lichen planus (OLP) is a carcinogenic chronic inflammatory oral disease, which lacks effective treatments. Fraxin is an active ingredient of the...
-
Except for Robust Outliers, Rapamycin Increases Lesion Burden in a Murine Model of Cerebral Cavernous Malformations
Cerebral cavernous malformation (CCM) is a hemorrhagic cerebrovascular disease where lesions develop in the setting of endothelial mutations of CCM ...
-
Metabolic profiling reveals circulating biomarkers associated with incident and prevalent Parkinson’s disease
The metabolic profile predating the onset of Parkinson’s disease (PD) remains unclear. We aim to investigate the metabolites associated with incident...
-
Metabolomic and lipidomic profiling of the spinal cord in type 2 diabetes mellitus rats with painful neuropathy
In this paper we investigated lipid and metabolite changes in diabetic neuropathy, using untargeted lipidomics and metabolomics analyses of the...
-
Quantifying myelin density in the feline auditory cortex
The cerebral cortex comprises many distinct regions that differ in structure, function, and patterns of connectivity. Current approaches to...
