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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive...
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Psychological and ethical issues raised by genomic in paediatric care pathway, a qualitative analysis with parents and childhood cancer patients
In paediatric oncology, genomics raises new ethical, legal and psychological issues, as somatic and constitutional situations intersect throughout...
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Gastrointestinal parasites of Wolffsohn’s viscacha (Chinchillidae: Lagidium wolffsohni), an endemic rodent species from the wild Patagonia
Parasites are ubiquitous in wildlife populations and have a profound impact on population dynamics. Interest in parasites of wildlife has increased...
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Orchestration of antiviral responses within the infected central nervous system
Many newly emerging and re-emerging viruses have neuroinvasive potential, underscoring viral encephalitis as a global research priority. Upon entry...
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First detection and a new avian host of the tick Ixodes ventalloi Gil Collado, 1936, in Slovakia
This study describes the first detection of Ixodes ventalloi in Slovakia. Two engorged females of I. ventalloi were collected from Dunnocks ( Prunella...
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A wingless fly on a winged mammal: host-parasite dynamics between Basilia travassosi (Diptera: Nycteribiidae) and Myotis lavali (Chiroptera: Vespertilionidae)
Nycteribiidae encompasses a specialized group of wingless blood-sucking flies that parasitize bats worldwide. Such relationships are frequently...
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Non-falciparum malaria infections in Uganda, does it matter? A review of the published literature
BackgroundPlasmodium falciparum is the dominant malaria species in the sub-Saharan Africa and the main cause of severe disease and death....
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Myhre syndrome in adulthood: clinical variability and emerging genotype-phenotype correlations
Myhre syndrome (MS, MIM 139210) is a rare multisystemic disorder caused by recurrent pathogenic missense variants in SMAD4 . The clinical features...
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The effect of single low-dose primaquine treatment for uncomplicated Plasmodium falciparum malaria on haemoglobin levels in Ethiopia: a longitudinal cohort study
BackgroundTo interrupt residual malaria transmission and achieve successful elimination of Plasmodium falciparum in low-transmission settings, the...
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How the brain can be trained to achieve an intermittent control strategy for stabilizing quiet stance by means of reinforcement learning
The stabilization of human quiet stance is achieved by a combination of the intrinsic elastic properties of ankle muscles and an active closed-loop...
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Temporal change in the parasite community of an invasive fish Trachelyopterus galeatus (Siluriformes: Auchenipteridae) in a neotropical floodplain
The construction of dams and hydroelectric plants affects biodiversity in aquatic environments and can facilitate the invasion of species. Few...
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Characteristics of the Structural Connectivity in Patients with Brain Injury and Chronic Health Symptoms: A Pilot Study
Diffusion properties from diffusion tensor imaging (DTI) are exquisitely sensitive to white matter abnormalities incurred during traumatic brain...
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Inconsistency of in vitro exsheathment triggers for gastrointestinal nematode parasites of sheep, cattle and deer
Exsheathment is crucial in the transition from free-living to parasitic phase for most strongyle nematode species. A greater understanding of this...
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Genetic constraint at single amino acid resolution in protein domains improves missense variant prioritisation and gene discovery
BackgroundOne of the major hurdles in clinical genetics is interpreting the clinical consequences associated with germline missense variants in...
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Expanding the phenotypic spectrum of CC2D2A-related ciliopathies: a rare homozygous nonsense variant in a patient with suspected nephronophthisis
Biallelic pathogenic variants in the gene CC2D2A cause a spectrum of ciliopathies, including Joubert and Meckel syndrome, which frequently involve...
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Pharmacogenetics in Italy: current landscape and future prospects
Pharmacogenetics investigates sequence of genes that affect drug response, enabling personalized medication. This approach reduces drug-induced...
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Examining geographical inequalities for malaria outcomes and spending on malaria in 40 malaria-endemic countries, 2010–2020
BackgroundWhile substantial gains have been made in the fight against malaria over the past 20 years, malaria morbidity and mortality are marked by...
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Short Tandem Repeats in the era of next-generation sequencing: from historical loci to population databases
In this study, we explore the landscape of short tandem repeats (STRs) within the human genome through the lens of evolving technologies to detect...
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Survey on Perkinsus species in two economic mussels (Mytilus coruscus and M. galloprovincialis) along the coast of the East China Sea and the Yellow Sea
Perkinsus , a parasitic pathogen of marine bivalves, is widely distributed among various mollusks in numerous countries. However, the prevalence and...
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Molecular characterizations of Cryptosporidium spp. in brown rat (Rattus norvegicus) from an animal feedlot in **njiang, China
Cryptosporidium infection is a common occurrence in rodents worldwide. In this study, 435 wild brown rats were captured from an animal feedlot in...