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Consumers’ knowledge and experiences of adverse drug reaction reporting in Australia: a national survey
AbstractThis study aimed to investigate the current knowledge and experiences of consumers in Australia on adverse drug reaction (ADR) reporting and...
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Identification of HOXC Gene Family as Prognostic and Immune-Related Biomarkers in Breast Cancer Through mRNA Transcriptional Profile and Experimental Validation
Breast cancer (BC) is the most common malignancy in women worldwide, and more effective biomarkers are urgently needed for the prevention and...
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A multi-biomarker micronucleus assay using imaging flow cytometry
Genetic toxicity testing assesses the potential of compounds to cause DNA damage. There are many genetic toxicology screening assays designed to...
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Establishing Virtual Bioequivalence and Clinically Relevant Specifications for Omeprazole Enteric-Coated Capsules by Incorporating Dissolution Data in PBPK Modeling
Currently, Biopharmaceutics Classification System (BCS) classes I and III are the only biological exemptions of immediate-release solid oral dosage...
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The power of trans-sodium crocetinate: exploring its renoprotective effects in a rat model of colistin-induced nephrotoxicity
Colistin, a multidrug-resistant gram-negative bacterial infection medication, has been associated with renal impairment and failure. Trans-sodium...
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Highly Sensitive and Selective Fluorescence and Smartphone-Based Sensor for Detection of Rutin Using Boron Nitrogen Co-doped Graphene Quantum Dots
This research explores the fluorescence properties and photostability of boron nitrogen co-doped graphene quantum dots (BN-GQDs), evaluating their...
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A genetic variant in the TAPBP gene enhances cervical cancer susceptibility by increasing m6A modification
Genetic variants can affect gene expression by altering the level of N6-methyladenosine (m 6 A) modifications. A better understanding of the...
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A Coaching-Based Leadership Program for Women Postdoctoral Fellows at the National Cancer Institute that Cultivates Self-confidence and Persistence in STEMM
Despite making strides in gender equality, women in Science, Technology, Engineering, Mathematics, and Medicine (STEMM) continue to face a persistent...
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A Review on Small Molecule Based Fluorescence Chemosensors for Bioimaging Applications
This review provides a thorough examination of small molecule-based fluorescence chemosensors tailored for bioimaging applications, showcasing their...
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Toxicological effect of acetaminophen, metamizole, and nimesulide cocktail on early development of zebrafish
BackgroundSeveral countries’ most incorrectly discarded medicines are acetaminophen (ACM), metamizole (MTZ), and nimesulide (NMS). These xenobiotics...
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Understand the Stabilization Engineering of Ascorbic Acid, Map** the Scheme for Stabilization, and Advancement.
AbstractVitamin C is extensively used in cosmetic formulation, howbeit stability is the supreme demerit that limits its use in beautifying products....
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Luteolin Mitigates D-Galactose-Induced Brain Ageing in Rats: SIRT1-Mediated Neuroprotection
Luteolin is an essential natural polyphenol found in a variety of plants. Numerous studies have supported its protective role in neurodegenerative...
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Transplant of fecal microbiota from healthy young mice relieves cognitive defects in late-stage diabetic mice by reducing metabolic disorders and neuroinflammation
Fecal microbiota transplant (FMT) is becoming as a promising area of interest for treating refractory diseases. In this study, we investigated the...
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Paclitaxel in colon cancer management: from conventional chemotherapy to advanced nanocarrier delivery systems
Paclitaxel, a potent chemotherapeutic agent derived from the bark of the Pacific yew tree, has demonstrated significant efficacy in the treatment of...
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Attention-based cross-frequency graph convolutional network for driver fatigue estimation
Fatigue driving significantly contributes to global vehicle accidents and fatalities, making driver fatigue level estimation crucial....
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Heterogeneity in choice models of addiction: the role of context
RationaleTheories of addiction guide scientific progress, funding priorities, and policy development and ultimately shape how people experiencing or...
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FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
The escalating obesity epidemic and aging population have propelled metabolic dysfunction-associated steatohepatitis (MASH) to the forefront of...
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Evaluation of the Protective Effects of Lugol’s Solution in Rats Poisoned with Aluminum Phosphide (Rice Tablets)
Aluminum phosphide (AlP) is the main component of rice tablets (a pesticide), which produces phosphine gas (PH3) when exposed to stomach acid. The...
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Carotid artery transplantation of brain endothelial cells enhances neuroprotection and neurorepair in ischaemic stroke rats
Brain microvascular endothelial cells (BMECs), an important component of the neurovascular unit, can promote angiogenesis and synaptic formation in...
