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Acute ethanol disrupts conditioned inhibition in the male rat
RationaleAlcohol can disrupt conditioned sexual inhibition (CSI) established by first-order conditioning in male rats. CSI can also be induced using...
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Ceftriaxone reverses diet-induced deficits in goal-directed control
RationaleObesity is associated with numerous health risks and ever-increasing rates are a significant global concern. However, despite weight loss...
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Reduced functional connectivity induced by longitudinal alterations of structure and perfusion may be associated with cognitive impairment in patients on maintenance hemodialysis
Hemodialysis (HD) leads to cognitive impairment; however, the pathophysiology of maintenance HD remains unclear. This study aimed to investigate the...
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Topological Organization of the Brain Network in Patients with Primary Angle-closure Glaucoma Through Graph Theory Analysis
Primary angle-closure glaucoma (PACG) is a sight-threatening eye condition that leads to irreversible blindness. While past neuroimaging research has...
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Neurobiological foundations and clinical relevance of effort-based decision-making
Applying effort-based decision-making tasks provides insights into specific variables influencing choice behaviors. The current review summarizes the...
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Changes of melatonin secretion in the neuropathic pain induced sleep disorder model rat
Chronic pain due to peripheral neuropathy can lead to sleep disorders that significantly worsen the patient's quality of life. Previously, we...
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Antidepressant-related microstructural changes in the external capsule
Several magnetic resonance imaging (MRI) studies have reported that antidepressant medications are strongly linked to brain microstructural...
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Cross-sectional and longitudinal evaluation of white matter microstructure damage and cognitive correlations by automated fibre quantification in relapsing-remitting multiple sclerosis patients
The purpose of this study was to characterize whole-brain white matter (WM) fibre tracts by automated fibre quantification (AFQ), capture subtle...
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C57BL/6J offspring mice reared by a single-mother exhibit, compared to mice reared in a biparental parenting structure, distinct neural activation patterns and heightened ethanol-induced anxiolysis
RationaleParenting experiences with caregivers play a key role in neurodevelopment. We recently reported that adolescents reared by a single-mother...
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Abnormal brain functional network dynamics in amyotrophic lateral sclerosis patients with depression
Since depression is common in amyotrophic lateral sclerosis (ALS) patients, we aimed to explore the specific brain functional network dynamics in ALS...
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Long-term effects of childhood single-parent family structure on brain connectivity and psychological well-being
The high and increasing proportion of single-parent families is considered a risk factor associated with various childhood trauma experiences....
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Co-administration of probiotics and vitamin D reduced disease severity and complications in patients with Parkinson’s disease: a randomized controlled clinical trial
RationaleProbiotics have beneficial effects on the nervous system by modulating the gut-brain axis. Additionally, vitamin D supplementation presents...
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Corticosterone after early adolescent stress prevents social avoidance, aversive behavior, and morphine-conditioned place preference in adulthood
RationaleStress during childhood or adolescence increases vulnerability to psychiatric disorders in adults. In adult rodents, the delayed effects of...
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The efficacy and safety of Zuranolone for treatment of depression: A systematic review and meta-analysis
RationaleZuranolone, a newly FDA-approved synthetic neurosteroid, shows promise in treating depression.
ObjectivesOur aim is to evaluate...
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Unlocking new avenues for neuropsychiatric disease therapy: the emerging potential of Peroxisome proliferator-activated receptors as promising therapeutic targets
RationalePeroxisome proliferator-activated receptors (PPARs) are transcription factors that regulate various physiological processes such as...
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Intrapartum exposure to synthetic oxytocin, maternal BMI, and neurodevelopmental outcomes in children within the ECHO consortium
BackgroundSynthetic oxytocin (sOT) is frequently administered during parturition. Studies have raised concerns that fetal exposure to sOT may be...
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Automated glioblastoma patient classification using hypoxia levels measured through magnetic resonance images
IntroductionThe challenge of treating Glioblastoma (GBM) tumors is due to various mechanisms that make the tumor resistant to radiation therapy. One...
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Psychedelic-assisted psychotherapy: where is the psychotherapy research?
RationalePsychedelic-assisted psychotherapy (PAP) has emerged as a potential treatment for a variety of mental health conditions, including substance...
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Visual training after central retinal loss limits structural white matter degradation: an MRI study
BackgroundMacular degeneration of the eye is a common cause of blindness and affects 8% of the worldwide human population. In adult cats with...
