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Replication of Akabane virus and related orthobunyaviruses in a fetal-bovine-brain-derived cell line
Akabane virus (AKAV), Aino virus, Peaton virus, Sathuperi virus, and Shamonda virus are arthropod-borne viruses belonging to the order Elliovirales ,...
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High efficacy of huCD20-targeted AcTaferon in humanized patient derived xenograft models of aggressive B cell lymphoma
Type I interferon (IFN) is a potent antitumoral drug, with an important history in the treatment of hematologic malignancies. However, its...
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Identification of novel compound heterozygous ZFP36L2 variants implicated in oocyte maturation defects and female infertility
PurposeTo explore the pathogenesis of oocyte maturation defects.
MethodsWhole exome sequencing was conducted to identify potential variants, which...
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Experience and training needs of nurses in military hospital on emergency rescue at high altitude: a qualitative meta-synthesis
BackgroundNurses play an important role in the treatment of war wounds on the plateau, and they face multiple challenges and a variety of needs in...
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Exploring the relationship between cyberloafing and innovativeness among nurses in research hospitals: a cross-sectional study in Turkey
BackgroundAlthough cyberloafing, which refers to employees' use of the internet for private purposes outside of work, is seen as a negative behavior;...
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Biochemical control in intermediate- and high-risk prostate cancer after EBRT with and without brachytherapy boost
PurposeExternal beam radiotherapy (EBRT) with or without brachytherapy boost (BTB) has not been compared in prospective studies using...
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Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer’s disease
BackgroundBeta-amyloid (Aβ) deposition in the brain parenchyma is a crucial initiating step in the amyloid cascade hypothesis of Alzheimer’s disease...
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Scope transition and early arterial inflow control provide safe and comfortable dissection in robotic distal pancreatectomy
PurposeWe describe details and outcomes of a novel technique for optimizing the surgical field during robotic distal pancreatectomy (RDP) for distal...
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Honokiol alleviates monosodium urate-induced gouty pain by inhibiting voltage-gated proton channels in mice
ObjectiveTo investigate whether honokiol (HNK) acted as an analgesic in connection with inhibiting the voltage-gated proton channel (Hv1).
...
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Dismantle and rebuild: the importance of preparedness and self-efficacy before, during and after allogeneic haematopoietic cell transplantation
PurposeThe aim of this study was to explore patients’ experiences of being prepared for allogenic haematopoietic cell transplantation and to explore...
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From “Husky” to “Bulldog”– behavioural correlates between castration and breed groups in the domestic dog (Canis lupus familiaris)
Neutering dogs is a widespread method and is carried out for various behavioural and husbandry reasons. This study’s main objective is to investigate...
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The trends of antihypertensive drug prescription based on the Japanese national data throughout the COVID-19 pandemic period
In 2020, concerns arose about the potential adverse effects of angiotensin II type 1 receptor blockers (ARBs) and angiotensin-converting enzyme...
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The Current Potential Pathogenesis of Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease mainly characterized by the accumulation of ubiquitinated proteins in the...
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Hotspots and trends in health-oriented physical literacy research: a visual analysis based on the WOS database
BackgroundThe World Health Organization has proposed that physical activity is a meaningful way to improve the quality of human life and reduce the...
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Review of clinical characteristics and mortality outcomes in patients on maintenance hemodialysis during the Omicron surge: a single center experience
BackgroundThis hemodialysis center experienced the pandemic from December 2022 to January 2023. Therefore, we sought to describe the clinical...
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Development of a porcine training model for microvascular fasciocutaneous free flap reconstruction
BackgroundIn reconstructive surgery, improvements are needed in the effective teaching of free flap surgery. There is a need for easily accessible...
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Interventions to increase vaccination in vulnerable groups: rapid overview of reviews
ObjectiveGroups which are marginalised, disadvantaged or otherwise vulnerable have lower uptake of vaccinations. This differential has been amplified...
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Advances in the isolation, cultivation, and identification of gut microbes
The gut microbiome is closely associated with human health and the development of diseases. Isolating, characterizing, and identifying gut microbes...
