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Article
Open AccessAn efficient parallel algorithm for Caputo fractional reaction-diffusion equation with implicit finite-difference method
An efficient parallel algorithm for Caputo fractional reaction-diffusion equation with implicit finite-difference method is proposed in this paper. The parallel algorithm consists of a parallel solver for line...
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Article
Open AccessDirect observation of multiple rotational stacking faults coexisting in freestanding bilayer MoS2
Electronic properties of two-dimensional (2D) MoS2 semiconductors can be modulated by introducing specific defects. One important type of defect in 2D layered materials is known as rotational stacking fault (RSF)...
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Article
Open AccessPolycystin-1 inhibits eIF2α phosphorylation and cell apoptosis through a PKR-eIF2α pathway
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in PKD1 or PKD2 which encodes polycystin-1 (PC1) and polycystin-2, respectively. PC1 was previously shown to slow cell proliferation and...
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Article
Open AccessThe cytotoxicity of coxsackievirus B3 is associated with a blockage of autophagic flux mediated by reduced syntaxin 17 expression
Coxsackievirus B3 (CVB3) is an important human pathogen linked to cardiac arrhythmias and acute heart failure. CVB3 infection has been reported to induce the formation of autophagosomes that support the viral ...
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Article
Open AccessExosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways
Viral myocarditis is potentially fatal and lacking a specific treatment. Exosomes secreted by cardiac progenitor cells (CPCs) have emerged as a promising tool for cardioprotection and repair. In this study, we...
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Article
Open AccessCongenital thrombocytopenia associated with GNE mutations in twin sisters: a case report and literature review
Neonatal thrombocytopenia is common in preterm and term neonates admitted to neonatal intensive care units. The etiology behind neonatal thrombocytopenia is complex. Inherited thrombocytopenia is rare and usua...
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Article
Open AccessIdentification of genetic determinants of hemolytic activity of Riemerella anatipestifer using random transposon mutagenesis
Riemerella anatipestifer causes epizootic infectious disease in poultry resulting in serious economic losses especially to the duck industry. In our previous study, R. anatipestifer was found to lyse duck erythro...
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Article
Open AccessThe role of clinical factors and immunocheckpoint molecules in the prognosis of patients with supratentorial extraventricular ependymoma: a single-center retrospective study
Supratentorial extraventricular ependymoma (SEE) is a rare subset of ependymomas located in the supratentorial parenchyma, and little is known regarding its management and prognosis. Our study aimed to reveal ...
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Article
Open AccessGate-tunable plasmons in mixed-dimensional van der Waals heterostructures
Surface plasmons, collective electromagnetic excitations coupled to conduction electron oscillations, enable the manipulation of light–matter interactions at the nanoscale. Plasmon dispersion of metallic struc...
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Article
Open AccessAn ADAMTS13 mutation that causes hereditary thrombotic thrombocytopenic purpura: a case report and literature review
Mutations in the ADAMTS13 gene can lead to an ADAMTS13 enzyme deficiency, which is related to Upshaw–Schulman syndrome (USS). USS is a common type of thrombotic thrombocytopenic purpura (TTP). Here we present a v...
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Article
Open AccessEffect of preoperative CT angiography examination on the clinical outcome of patients with BMI ≥ 25.0 kg/m2 undergoing laparoscopic gastrectomy: study protocol for a multicentre randomized controlled trial
Gastric cancer, which is the fifth most common malignancy and the third most common cause of cancer-related death, is particularly predominant in East Asian countries, such as China, Japan and Korea. It is a s...
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Article
Open AccessBVES is a novel interactor of ANO5 and regulates myoblast differentiation
Anoctamin 5 (ANO5) is a membrane protein belonging to the TMEM16/Anoctamin family and its deficiency leads to the development of limb girdle muscular dystrophy R12 (LGMDR12). However, little has been known abo...
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Article
Open AccessTFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1
CVB3 is a single positive-strand enterovirus, and a common pathogen in myocarditis etiology. Although a number of antiviral candidates are under development, specific targeted therapy is not available for CVB3...
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Article
Post-traumatic growth in adult patients with systemic lupus erythematosus: a cross-sectional study in China
This cross-sectional study aims to evaluate the post-traumatic growth (PTG) level and explores its predictors among adult patients with SLE in China. From April 2020 to April 2021, 135 hospitalized adult SLE p...
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Article
Open AccessThermodynamic behavior of correlated electron-hole fluids in van der Waals heterostructures
Coupled two-dimensional electron-hole bilayers provide a unique platform to study strongly correlated Bose-Fermi mixtures in condensed matter. Electrons and holes in spatially separated layers can bind to form...
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Article
Open AccessAcetylation of FOXO1 activates Bim expression involved in CVB3 induced cardiomyocyte apoptosis
Viral myocarditis (VMC) is the major reason for sudden cardiac death among both children and young adults. Of these, coxsackievirus B3 (CVB3) is the most common causative agent of myocarditis. Recently, the ro...
