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Article
Open AccessEstablishment of a neutrophil extracellular trap-related prognostic signature for colorectal cancer liver metastasis and expression validation of CYP4F3
Liver metastasis stands as the primary contributor to mortality among patients diagnosed with colorectal cancer (CRC). Neutrophil extracellular traps (NETs) emerge as pivotal players in the progression and met...
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Chapter and Conference Paper
Research on Permeability Prediction Method of CO2 Storage Layer Based on Random Forest
CO2 geological storage technology is considered as an effective measure to reduce atmospheric CO2 concentration and is one of the key technologies to achieve the goal of carbon neutrality in China. Reservoir perm...
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Article
Safety and Efficacy of Endovascular Aortic Repair for Abdominal Aortic Aneurysms with a Hostile Neck Anatomy
This study aimed to investigate the safety and efficacy of endovascular aortic repair (EVAR) for the treatment of an abdominal aortic aneurysm (AAA) with a hostile neck anatomy (HNA).
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Article
Formation mechanism of core discing during drilling under deep in-situ stress environment: Numerical simulation and laboratory testing
Core discing often occurs during drilling under deep in-situ stress environment. To determine its formation mechanism in sandstone under deep in-situ stress environment, PFC2D was used to study the crack distr...
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Article
Open AccessA radiomics nomogram prediction for survival of patients with “driver gene-negative” lung adenocarcinomas (LUAD)
To study the role of computed tomography (CT)-derived radiomics features and clinical characteristics on the prognosis of “driver gene-negative” lung adenocarcinoma (LUAD) and to explore the potential molecula...
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Article
LncRNA GNAS-AS1 knockdown inhibits keloid cells growth by mediating the miR-188-5p/RUNX2 axis
Keloid is a common dermis tumor, occurring repeatedly, affecting the quality of patients’ life. Long non-coding RNAs (lncRNAs) have crucial regulatory capacities in skin scarring formation and subsequent scar ...
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Article
Open AccessUSF2-mediated upregulation of TXNRD1 contributes to hepatocellular carcinoma progression by activating Akt/mTOR signaling
Thioredoxin reductase 1 (TXNRD1) is one of the major redox regulators in mammalian cells, which has been reported to be involved in tumorigenesis. However, its roles and regulatory mechanism underlying the pro...
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Article
Open AccessExosomes from mmu_circ_0001052-modified adipose-derived stem cells promote angiogenesis of DFU via miR-106a-5p and FGF4/p38MAPK pathway
Diabetic foot ulcer (DFU) is a chronic infectious disease caused by diabetes mellitus (DM). Angiogenesis plays the decisive role in wound healing of DFU. Adipose-derived stem cells (ADSCs) can ameliorate angio...
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Article
Open AccessMaelstrom promotes tumor metastasis through regulation of FGFR4 and epithelial-mesenchymal transition in epithelial ovarian cancer
Increasing evidence has indicated that Maelstrom (MAEL) plays an oncogenic role in various human carcinomas. However, the exact function and mechanisms by which MAEL acts in epithelial ovarian cancer (EOC) rem...
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Article
Open AccessPositive regulation of ataxia-telangiectasia-mutated protein (ATM) by E2F transcription Factor 1 (E2F-1) in cisplatin-resistant nasopharyngeal carcinoma cells
To explore the mechanism of E2F transcription Factor 1 (E2F-1)-mediated ataxia-telangiectasia-mutated protein (ATM) in cisplatin (DDP)-resistant nasopharyngeal carcinoma (NPC).
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Article
Fire-prone Rhamnaceae with South African affinities in Cretaceous Myanmar amber
The rapid Cretaceous diversification of flowering plants remains Darwin’s ‘abominable mystery’ despite numerous fossil flowers discovered in recent years. Wildfires were frequent in the Cretaceous and many suc...
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Article
Integrated Towing Transportation Technique for Offshore Wind Turbine with Composite Bucket Foundation
Composite bucket foundation and one-step installation technology for offshore wind turbine are the integration of foundation construction, transportation and whole installation at sea. The cost of offshore win...
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Article
Balance scientific and ethical concerns to achieve a nuanced perspective on ‘blood amber’
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Article
Open AccessCoronavirus disease 2019 outbreak in Bei**g’s **nfadi Market, China: a modeling study to inform future resurgence response
A local coronavirus disease 2019 (COVID-19) case confirmed on June 11, 2020 triggered an outbreak in Bei**g, China after 56 consecutive days without a newly confirmed case. Non-pharmaceutical interventions (N...
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Article
Open AccessFluorescence polarization assay improves the rapid detection of human brucellosis in China
Brucellosis is an infectious-allergic zoonotic disease caused by bacteria of the genus Brucella. Early diagnosis is the key to preventing, treating, and controlling brucellosis. Fluorescence polarization immunoas...
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Article
A Fast Compression Framework Based on 3D Point Cloud Data for Telepresence
In this paper, a novel compression framework based on 3D point cloud data is proposed for telepresence, which consists of two parts. One is implemented to remove the spatial redundancy, i.e., a robust Bayesian...
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Article
Influence of heat treatment on microstructure and nanohardness of TiAl alloy solidified under high pressure
The Ti-48at.%Al alloy solidified under different pressures was prepared using a tungsten-carbide six-anvil apparatus and then heat treated at different temperatures. The effect of heat treatment on microstruct...
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Article
The structural, electronic, magnetic, and optical properties of the Cr-, Mo-, and W-doped ZnTe alloys
The first-principle method is adopted to study do** of different atoms X (X = Cr, Mo, or W) in ZnTe compound. The spin-down bandgaps of the X-doped Zn0.96875X0.03125Te alloys are 1.368, 1.415, and 1.399 eV for ...
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Article
Open AccessSafety and efficacy assessment of allogeneic human dental pulp stem cells to treat patients with severe COVID-19: structured summary of a study protocol for a randomized controlled trial (Phase I / II)
To assess the safety and therapeutic effects of allogeneic human dental pulp stem cells (DPSCs) in treating severe pneumonia caused by COVID-19.
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Article
Implications on the origin of cosmic rays in light of 10 TV spectral softenings
Precise measurements of the energy spectra of cosmic rays (CRs) show various kinds of features deviating from single power-laws, which give very interesting and important implications on their origin and propa...