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  1. Article

    Open Access

    Insight into binding of endogenous neurosteroid ligands to the sigma-1 receptor

    The sigma-1 receptor (σ1R) is a non-opioid membrane receptor, which responds to a diverse array of synthetic ligands to exert various pharmacological effects. Meanwhile, candidates for endogenous ligands of σ1...

    Chunting Fu, Yang **ao, **aoming Zhou, Ziyi Sun in Nature Communications (2024)

  2. Article

    Open Access

    Enhancing efficiency of protein language models with minimal wet-lab data through few-shot learning

    Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Pre-trained protein language models have achieved state-of-the-art performance in predicting protein fitness w...

    Ziyi Zhou, Liang Zhang, Yuanxi Yu, Banghao Wu, Mingchen Li in Nature Communications (2024)

  3. Article

    Open Access

    Macrophage-derived CD36 + exosome subpopulations as novel biomarkers of Candida albicans infection

    Invasive candidiasis (IC) is a notable healthcare-associated fungal infection, characterized by high morbidity, mortality, and substantial treatment costs. Candida albicans emerges as a principal pathogen in this...

    Shuo Li, Yanyan Xv, Yuanyuan Sun, Ziyi Shen, Ruiying Hao in Scientific Reports (2024)

  4. Article

    Open Access

    Author Correction: Waveguide-integrated twisted bilayer graphene photodetectors

    Qinci Wu, Jun Qian, Yuechen Wang, Luwen **ng, Ziyi Wei, **n Gao in Nature Communications (2024)

  5. Article

    Open Access

    Experimental study on fractal dimension of energy dissipation and crack growth in saturated tuff at different strain rates

    In order to investigate the effects of strain rate and water saturation on the energy dissipation and crack growth of tuff, uniaxial compression tests were carried out on dry and water saturated tuff with diff...

    Hao Wang, Qi Zong, Ziyi Lu, Haibo Wang in Scientific Reports (2024)

  6. Article

    Open Access

    Research on safety condition assessment methodology for single tower steel box girder suspension bridges over the sea based on improved AHP-fuzzy comprehensive evaluation

    In order to propose a reliable method for assessing the safety condition for single-tower steel box girder Suspension bridges over the sea, a condition monitoring system is established by installing sensors on...

    Huifeng Su, Cheng Guo, Ziyi Wang, Tao Han, David Bonfils Kamanda in Scientific Reports (2024)

  7. Article

    Open Access

    Construction of TiO2/WO3/TiO2 double heterojunction films for excellent electrochromic performance

    Electrochromic devices are applied extensively to camouflages, smart windows, heat insulation layers, and automobile rearview mirrors, etc. The amorphous WO3 is a very attractive electrochromic material, whereas ...

    Zhengqiao Lv, Di Yang, Jianwei Mo, Ziyi **, Shuai Chang in Scientific Reports (2024)

  8. Article

    Open Access

    Fine-grained recognition of bitter gourd maturity based on Improved YOLOv5-seg model

    Bitter gourd, being perishable, requires timely harvesting. Delayed harvesting can result in a substantial reduction in fruit quality. while premature harvesting leads to underdeveloped fruit and decreased yie...

    Sheng Jiang, Jiangbo Ao, Hualin Yang, Fangnan **e, Ziyi Liu in Scientific Reports (2024)

  9. Article

    Open Access

    CASi: A framework for cross-timepoint analysis of single-cell RNA sequencing data

    Single-cell RNA sequencing (scRNA-seq) technology has been widely used to study the differences in gene expression at the single cell level, providing insights into the research of cell development, differenti...

    Yizhuo Wang, Christopher R. Flowers, Michael Wang, Xuelin Huang in Scientific Reports (2024)

  10. Article

    Open Access

    Distributed electrified heating for efficient hydrogen production

    This study introduces a distributed electrified heating approach that is able to innovate chemical engineering involving endothermic reactions. It enables rapid and uniform heating of gaseous reactants, facili...

    Hanmin Yang, Ilman Nuran Zaini, Ruming Pan, Yanghao ** in Nature Communications (2024)

  11. Article

    Open Access

    Waveguide-integrated twisted bilayer graphene photodetectors

    Graphene photodetectors have exhibited high bandwidth and capability of being integrated with silicon photonics (SiPh), holding promise for future optical communication devices. However, they usually suffer fr...

    Qinci Wu, Jun Qian, Yuechen Wang, Luwen **ng, Ziyi Wei, **n Gao in Nature Communications (2024)

  12. Article

    Open Access

    CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age

    Influenza B viruses (IBVs) cause substantive morbidity and mortality, and yet immunity towards IBVs remains understudied. CD8+ T-cells provide broadly cross-reactive immunity and alleviate disease severity by rec...

    Tejas Menon, Patricia T. Illing, Priyanka Chaurasia in Nature Communications (2024)

  13. Article

    Open Access

    Topological perturbations on resilience of the world trade competition network

    Network resilience refers to a system’s capability to adapt its functions to ensure continuity of essential operations amidst external environmental shifts or internal failures. The resilience of the world tra...

    Zhao Li, Ren Zhuoming, Zhao Ziyi in Humanities and Social Sciences Communicati… (2024)

  14. Article

    Open Access

    Room-temperature stabilizing strongly competing ferrielectric and antiferroelectric phases in PbZrO3 by strain-mediated phase separation

    PbZrO3 has been broadly considered as a prototypical antiferroelectric material for high-power energy storage. A recent theoretical study suggests that the ground state of PbZrO3 is threefold-modulated ferrielect...

    Ziyi Yu, Ningbo Fan, Zhengqian Fu, Biao He, Shiguang Yan in Nature Communications (2024)

  15. Article

    Open Access

    Iron status and sarcopenia-related traits: a bi-directional Mendelian randomization study

    Although serum iron status and sarcopenia are closely linked, the presence of comprehensive evidence to establish a causal relationship between them remains insufficient. The objective of this study is to empl...

    Honggu Chen, Ziyi Zhang, Yizhe Wang, Anpei Ma, Lingbo Li in Scientific Reports (2024)

  16. Article

    Open Access

    Parameter optimization of vibration control system for adjacent building structures based on negative stiffness inerter damper

    Building structures are subjected to strong earthquakes, which result in lateral collisions between them. Such collisions often cause severe structural damage and exacerbate the seismic hazard risk of building...

    **aofang Kang, Jianjun Tang, Jiachen Wei, Xueqin Jiang, Ziyi Sheng in Scientific Reports (2024)

  17. Article

    Open Access

    Digital inclusive finance, green technological innovation, and carbon emissions from a spatial perspective

    Based on the panel data of 276 prefecture-level cities in China from 2011 to 2020, this study explores the impact of digital inclusive finance (DIF) on carbon emissions and the intrinsic mechanism of green tec...

    Yang Lu, Ziyi **a in Scientific Reports (2024)

  18. Article

    Open Access

    Predicting the effect of chemicals on fruit using graph neural networks

    The neural network method is a type of machine learning that has made significant advances over the past few years in a variety of fields, particularly text, speech, images, videos, etc. In areas where data is...

    Junming Han, Tong Li, Yun He, Ziyi Yang in Scientific Reports (2024)

  19. Article

    Open Access

    Involution of brown adipose tissue through a Syntaxin 4 dependent pyroptosis pathway

    Aging, chronic high-fat diet feeding, or housing at thermoneutrality induces brown adipose tissue (BAT) involution, a process characterized by reduction of BAT mass and function with increased lipid droplet si...

    **aofan Yu, Gabrielle Benitez, Peter Tszki Wei, Sofia V. Krylova in Nature Communications (2024)

  20. Article

    Open Access

    Recent autumn sea ice loss in the eastern Arctic enhanced by summer Asian-Pacific Oscillation

    Recent rapid Arctic sea ice loss was documented as combined results from anthropogenic forcing and climate system internal variability. However, the role of internal variability is not well understood. Here, w...

    Botao Zhou, Ziyi Song, Zhicong Yin, ** Xu, Bo Sun in Nature Communications (2024)

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